Prion protein is necessary for latent learning and long-term memory retention.

Molecular Biology of Prion Diseases

1991 • 1,978 citations

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein

1994 • 1,802 citations

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1992 • 1,632 citations

Control of Memory Formation Through Regulated Expression of a CaMKII Transgene

1996 • 1,525 citations

Prion protein is necessary for normal synaptic function

1994 • 802 citations

Altered circadian activity rhythms and sleep in mice devoid of prion protein

1996 • 655 citations

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

1994 • 563 citations

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene

1996 • 483 citations

Developmental expression of the prion protein gene in glial cells

1995 • 321 citations

Correlations between immediate early gene induction and the persistence of long-term potentiation

1993 • 297 citations

Dissection of memory formation: from behavioral pharmacology to molecular genetics

1995 • 277 citations

Hippocampal slices from prion protein null mice: disrupted Ca2+-activated K+ currents

1996 • 184 citations

Prion Diseases and Neurodegeneration

1994 • 163 citations

Accumulation of proteinase K-resistant prion protein (PrP) is restricted by the expression level of normal PrP in mice inoculated with a mouse-adapted strain of the Creutzfeldt-Jakob disease agent

1995 • 139 citations

Rapid anterograde axonal transport of the cellular prion glycoprotein in the peripheral and central nervous systems.

1994 • 126 citations

Infrapyramidal mossy fibers and two-way avoidance learning: developmental modification of hippocampal circuitry and adult behavior of rats and mice

1988 • 116 citations

Structure and polymorphism of the mouse prion protein gene.

1994 • 104 citations

Ultrastructural localization of cellular prion protein (PrPc) in synaptic boutons of normal hamster hippocampus.

1995 • 100 citations

Vasopressin potentiation in the performance of a learned appetitive task: Reversal by a pressor antagonist analog of vasopressin

1983 • 79 citations

Age-related deterioration in conditional avoidance task in the SAM-P/10 mouse, an animal model of spontaneous brain atrophy

1993 • 63 citations

Prion protein is strongly immunolocalized at the postsynaptic domain of human normal neuromuscular junctions

1993 • 46 citations