Transcriptional Control of the Human Heme Oxygenase-1 Gene by Stress

Bilirubin Is an Antioxidant of Possible Physiological Importance

1987 • 3,406 citations

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

1968 • 1,767 citations

METALLOTHIONEIN

1986 • 1,606 citations

Biochemical Effects of Mercury, Cadmium, and Lead

1972 • 1,464 citations

Microsomal Heme Oxygenase

1969 • 1,348 citations

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.

1989 • 1,273 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

Antioxidant activity of albumin-bound bilirubin.

1987 • 763 citations

Does carbon monoxide have a physiological function?

1991 • 425 citations

The enzymatic catabolism of hemoglobin: stimulation of microsomal heme oxygenase by hemin.

1970 • 396 citations

Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences

1985 • 353 citations

Human heme oxygenase cDNA and induction of its mRNA by hemin

1988 • 320 citations

Reduced nicotinamide adenine dinucleotide phosphate dependent biliverdin reductase. Partial purification and characterization

1970 • 264 citations

The human 32‐kDa stress protein induced by exposure to arsenite and cadmium ions is heme oxygenase

1989 • 163 citations

Metal-responsive elements act as positive modulators of human metallothionein-IIA enhancer activity.

1987 • 152 citations

Characterization of the enzyme

1994 • 134 citations

Identification of a cis-acting element that is responsible for cadmium-mediated induction of the human heme oxygenase gene.

1994 • 130 citations

[Regulation of heme oxygenase gene expression].

1989 • 106 citations

Interaction of upstream stimulatory factor with the human heme oxygenase gene promoter

1990 • 62 citations

Identification of a cis-regulatory element and putative trans-acting factors responsible for 12-O-tetradecanoylphorbol-13-acetate (TPA)-mediated induction of heme oxygenase expression in myelomonocytic cell lines.

1993 • 57 citations

Regulation of heme protein synthesis

1994 • 52 citations

The rapid and decremental change in haem oxygenase mRNA during erythroid differentiation of murine erythroleukaemia cells

1989 • 30 citations

Differential Control of the Metal-Mediated Activation of the Human Heme Oxygenase-1 and Metallothionein IIa Genes

1995 • 29 citations