Localizing the alpha-1 Adrenergic Receptor in the Central Nervous System

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

A STUDY OF THE ADRENOTROPIC RECEPTORS

1948 • 2,856 citations

Nucleus locus ceruleus: new evidence of anatomical and physiological specificity

1983 • 1,877 citations

The central adrenergic system. An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine‐B‐hydroxylase as a marker

1975 • 1,454 citations

Central Catecholamine Neuron Systems: Anatomy and Physiology of the Norepinephrine and Epinephrine Systems

1979 • 1,361 citations

Efferent connections of the parabrachial nucleus in the rat

1980 • 1,187 citations

The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat

1982 • 1,128 citations

Immunohistochemical evidence for the existence of adrenaline neurons in the rat brain

1974 • 1,097 citations

The concentration of sympathin in different parts of the central nervous system under normal conditions and after the administration of drugs

1954 • 1,014 citations

On some physiological actions of ergot

1906 • 980 citations

Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study

1977 • 835 citations

A new method for receptor autoradiography: [3H]Opioid receptors in rat brain

1979 • 797 citations

Afferent connections to the sensory trigeminal nuclei, the nucleus of the solitary tract and adjacent structures. An experimental study in the rat

1956 • 754 citations

Distribution of α2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents

1984 • 719 citations

An organizing principle for cerebral function : the unit module and the distributed system

1978 • 699 citations

Binding characteristics of a radiolabeled agonist and antagonist at central nervous system alpha noradrenergic receptors.

1977 • 544 citations

Quantitative receptor autoradiography using [3H]Ultrofilm: application to multiple benzodiazepine receptors

1982 • 529 citations

A radioautographic study of the efferent pathways of the nucleus locus coeruleus

1974 • 500 citations

Catecholamine innervation of the basal forebrain II. Amygdala, suprarhinal cortex and entorhinal cortex

1978 • 487 citations

Light microscopic localization of brain opiate receptors: a general autoradiographic method which preserves tissue quality

1982 • 466 citations

The monoamine innervation of rat cerebral cortex: Synaptic and nonsynaptic axon terminals

1978 • 448 citations

Depletion of Brain Catecholamines: Failure of Ocular Dominance Shift After Monocular Occlusion in Kittens

1976 • 438 citations

Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists

1980 • 435 citations

Noradrenergic alpha 1 and alpha 2 receptors: light microscopic autoradiographic localization.

1980 • 421 citations

Binding characteristics of 3H-prazosin to rat brain α-adrenergic receptors

1979 • 419 citations

Neuroanatomy of Central Cardiovascular Control. Nucleus Tractus Solitarii: Afferent and Efferent Neuronal Connections in Relation to the Baroreceptor Reflex Arc

1977 • 388 citations

Restoration of visual cortical plasticity by local microperfusion of norepinephrine

1979 • 365 citations

Quantitative autoradiography of beta 1- and beta 2-adrenergic receptors in rat brain.

1984 • 349 citations

Projections of the nucleus locus coeruleus in the albino rat

1969 • 338 citations

Origin and organization of brainstem catecholamine innervation in the rat

1979 • 316 citations

Preservation of binocularity after monocular deprivation in the striate cortex of kittens treated with 6‐Hydroxydopamine

1979 • 313 citations

Direct projections from the A5 catecholamine cell group to the intermediolateral cell column

1979 • 287 citations

Benzodiazepine receptors are coupled to a subpopulation of gamma-aminobutyric acid (GABA) receptors: evidence from a quantitative autoradiographic study.

1981 • 262 citations

HIGH RESOLUTION AUTORADIOGRAPHY WITH DRY MOUNTED, FREEZE-DRIED FROZEN SECTIONS COMPARATIVE STUDY OF SIX METHODS USING TWO DIFFUSIBLE COMPOUNDS H-ESTRADIOL AND H-MESOBILIRUBINOGEN

1966 • 256 citations

The distribution and orientation of noradrenergic fibers in neocortex of the rat: An immunofluorescence study

1978 • 255 citations

Quantitative film autoradiography for tritium: Methodological considerations

1985 • 239 citations

Anatomy of brain alpha₁‐adrenergic receptors: In vitro autoradiography with [¹²⁵I]‐heat

1985 • 238 citations

Adrenaline neurons in the rostral ventrolateral medulla innervate thoracic spinal cord: A combined immunocytochemical and retrograde transport demonstration

1981 • 238 citations

Catecholamine innervation of the basal forebrain III. Olfactory bulb, anterior olfactory nuclei, olfactory tubercle and piriform cortex

1978 • 223 citations

Nervous System and Hypertension

1978 • 217 citations

Quantitative receptor mapping by autoradiography: some current technical problems

1985 • 204 citations

Adrenaline synthesizing neurons in the rostral ventrolateral medulla: a possible role in tonic vasomotor control

1983 • 186 citations

Region‐specific distribution of catecholamine afferents in primate cerebral cortex: A fluorescence histochemical analysis

1984 • 185 citations

Characteristics and function of opioids

1979 • 174 citations

Ultrastructural demonstration of noradrenergic synapses in the rat central nervous system by dopamine-beta-hydroxylase immunocytochemistry.

1981 • 165 citations

The intra-cortical trajectory of the coeruleo-cortical projection in the rat: A tangentially organized cortical afferent

1981 • 162 citations

Afferent projections to cardiovascular portions of the nucleus of the tractus solitarius in the rat

1981 • 159 citations

Andrenergic receptive mechanism of canine ileum.

1959 • 150 citations

Beta adrenergic receptor localization in rat brain by light microscopic autoradiography

1982 • 143 citations

Characteristics and function of opioids.

1978 • 142 citations

Alpha adrenoceptors in rat brain: Direct identification with prazosin

1979 • 136 citations

[125I]BE 2254, a new high affinity radioligand for α1-adrenoceptors

1981 • 131 citations

α1-adrenoceptor-mediated responses in the lateral geniculate nucleus are enhanced by chronic antidepressant treatment

1981 • 130 citations

Quantitative receptor autoradiography: tissue defatting eliminates differential self-absorption of tritium radiation in gray and white matter of brain

1984 • 126 citations

Central Nervous Integration of Cardiovascular Control

1982 • 122 citations

Prazosin selectively antagonizes neuronal responses mediated by ?1-adrenoceptors in brain

1981 • 121 citations

3H-prazosin binds specifically to ??1?-Adrenoceptors in rat brain

1980 • 112 citations

Activation of lateral geniculate neurons by norepinephrine: Mediation by an α-adrenergic receptor

1980 • 110 citations

Noradrenergicα1 and α2 receptors: Autoradiographic visualization

1979 • 103 citations

Quantitative measurement of local cerebral metabolic rate for glucose utilizing tritiated 2-deoxyglucose

1981 • 93 citations

Quantitative autoradiography of [3H]prazosin binding sites in rat forebrain

1983 • 87 citations

Norepinephrine-containing terminals in kitten visual cortex: Laminar distribution and ultrastructure

1981 • 84 citations

Development of α‐Noradrenergic and Dopaminergic Receptor Systems Depends on Maturation of Their Presynaptic Nerve Terminals in the Rat Brain

1981 • 80 citations

Adrenoceptors on central neurones: Microelectrophoretic studies

1979 • 71 citations

Alpha-adrenoceptive influences on the control of the sleep-waking cycle in the cat

1980 • 69 citations

[3H]WB4101—Caution about its role as an alpha-adrenergic subtype selective radioligand

1980 • 66 citations

[125I]-HEAT, a selective, high-affinity, high specific activity ligand for alpha1-adrenoceptors

1981 • 57 citations

The alpha-adrenergic receptor: Radiohistochemical analysis of functional characteristics and biochemical differences

1985 • 57 citations

Postnatal development of brain alpha1-adrenergic receptors: In vitro autoradiography with [125i]HEAT in normal rats and rats treated with alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase

1985 • 57 citations

The organization of the catecholamine innervation of somatosensory cortex: the barrel field of the mouse

1978 • 47 citations

Selectivity of a series of clonidine-like drugs for α1 and α2 adrenoceptors in rat brain

1980 • 46 citations

Central and peripheral prazosin binding: An in vitro autoradioraphic study in the rat

1982 • 41 citations

Multiple central WB-4101 binding sites and the selectivity of prazosin

1980 • 34 citations

A correlative radioautographic, fluorescent, and histochemical technique for cytopharmacology.

1974 • 34 citations

Pulmonary α-adrenoceptors: Autoradiographic localization using [3H]prazosin

1983 • 29 citations

In ethanol

1982 • 27 citations

Regional distribution of rat brain alpha1-adrenergic receptors: Correlation between (125I)-heat membrane binding and autoradiography

1985 • 24 citations

Preferential blockade of postsynaptic α-adrenoceptors by BE 2254

1981 • 23 citations

Regional heterogeneity of two high affinity binding sites for 3H-WB-4101 in mouse brain

1980 • 23 citations

[125I]-HEAT: Fifty percent of the ligand can bind to the alpha1-adrenoceptors with extremely high affinity

1982 • 22 citations

Brain α1-adrenergic receptors: Suitability of [125I]heat as a radioligand for in vitro autoradiography

1983 • 17 citations

An autoradiographic demonstration of prazosin binding to arterial vessels in the rat

1982 • 7 citations

Rapid and simple purification of the 125I-labeled α-1 adrenergic radioligand 2-[β-(4-hydroxylphenylethyl)aminomethyl] tetralone (BE 2254) using reversed-phase high-performance liquid chromatography

1985 • 2 citations