Effect of Campath-1H antibody on human hematopoietic progenitors in vitro

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Reshaping human antibodies for therapy

1988 • 1,555 citations

REMISSION INDUCTION IN NON-HODGKIN LYMPHOMA WITH RESHAPED HUMAN MONOCLONAL ANTIBODY CAMPATH-1H

1988 • 703 citations

Long-term culture of human bone marrow cells.

1980 • 624 citations

ELIMINATION OF GRAFT-VERSUS-HOST DISEASE BY IN-VITRO DEPLETION OF ALLOREACTIVE LYMPHOCYTES WITH A MONOCLONAL RAT ANTI-HUMAN LYMPHOCYTE ANTIBODY (CAMPATH-1)

1984 • 436 citations

Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement

1983 • 365 citations

Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype

1989 • 356 citations

Humanised monoclonal antibody therapy for rheumatoid arthritis

1992 • 316 citations

Bone marrow transplantation for patients with chronic myeloid leukaemia: T-cell depletion with Campath-1 reduces the incidence of graft-versus-host disease but may increase the risk of leukaemic relapse.

1986 • 298 citations

Bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: importance of a graft‐versus‐leukaemia effect

1988 • 201 citations

T CELL DEPLETION WITH CAMPATH-1 IN ALLOGENEIC BONE MARROW TRANSPLANTATION

1988 • 189 citations

IMPORTANCE OF ANTIGEN SPECIFICITY FOR COMPLEMENT‐MEDIATED LYSIS BY MONOCLONAL ANTIBODIES

1988 • 152 citations

Therapeutic potential of rat monoclonal antibodies: isotype specificity of antibody-dependent cell-mediated cytotoxicity with human lymphocytes.

1985 • 147 citations

A cell line secreting stimulating factors for CFU-GEMM culture

1984 • 113 citations

The Depletion of T Cell Subsets in Vitro and in Vivo

1986 • 105 citations

Randomised Controlled Clinical Trials

1996 • 85 citations

Remission Induction in Patients with Lymphoid Malignancies Using Unconjugated CAMPATH-1 Monoclonal Antibodies

1990 • 78 citations

Ex vivo T‐cell depletion with the monoclonal antibody Campath‐1 plus human complement effectively prevents acute graft‐versus‐host disease in allogeneic bone marrow transplantation

1986 • 76 citations

The use of bone marrow cells grown in long-term culture for autologous bone marrow transplantation in acute myeloid leukaemia: an update.

1989 • 75 citations

Reactivity of rat monoclonal antibody CAMPATH‐1 with human leukaemia cells and its possible application for autologous bone marrow transplantation

1985 • 71 citations

Isolation of low-frequency class-switch variants from rat hybrid myelomás

1987 • 67 citations

CAMPATH-1M—PROPHYLACTIC USE AFTER KIDNEY TRANSPLANTATION

1989 • 63 citations

Effects of monoclonal anti-lymphocyte antibodies in vivo in monkeys and humans.

1983 • 58 citations

Monoclonal Antibody Therapy of Cancer

2007 • 50 citations

Reversal of allograft rejection using the monoclonal antibody, Campath-1G.

1991 • 49 citations

Removal of T cells from bone marrow for transplantation. Comparison of rat monoclonal anti-lymphocyte antibodies of different isotypes.

1983 • 44 citations

THE REPOPULATION CAPACITY OF BONE MARROW GRAFTS FOLLOWING PRETREATMENT WITH MONOCLONAL ANTIBODIES AGAINST T LYMPHOCYTES IN RHESUS MONKEYS

1988 • 43 citations

PREVENTION OF GRAFT-VERSUS-HOST DISEASE IN ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR LEUKEMIA BY T-CELL DEPLETION INVITRO PRIOR TO TRANSPLANTATION

1985 • 27 citations

New approaches for the prevention of rejection and graft-vs.-host disease in clinical bone marrow transplantation.

1986 • 22 citations

Clonal and long-term cultures using human bone marrow

1992 • 22 citations

Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement

1983 • 16 citations

Infectious complications after allogeneic bone marrow transplantation with and without T-cell depletion of donor marrow

1989 • 15 citations

Current developments in marrow transplantation.

1987 • 15 citations

A cell line secreting stimulating factors for CFU-GEMM culture

1984 • 11 citations

The effect of in vitro T lymphocyte depletion on generation of IL2-activated cytotoxic cells.

1991 • 9 citations

Optimal conditions for in vitro T cell depletion of human bone marrow by Campath-1a plus complement as demonstrated by limiting dilution analysis.

1989 • 9 citations

Monoclonal antibody therapy of cancer.

1990 • 8 citations