Chronic granulomatous disease due to granulocytes with abnormal NADPH oxidase activity and deficient cytochrome-b

The Determination of Enzyme Dissociation Constants

1934 • 11,865 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

In Vitro Bactericidal Capacity of Human Polymorphonuclear Leukocytes: Diminished Activity in Chronic Granulomatous Disease of Childhood *

1967 • 932 citations

The particulate superoxide-forming system from human neutrophils. Properties of the system and further evidence supporting its participation in the respiratory burst.

1976 • 350 citations

Novel cytochrome b system in phagocytic vacuoles of human granulocytes

1978 • 335 citations

Characteristics of the cofactor requirements for the superoxide-generating NADPH oxidase of human polymorphonuclear leukocytes

1981 • 251 citations

Chronic Granulomatous Disease

1977 • 209 citations

Use of lipophilic probes of membrane potential to assess human neutrophil activation. Abnormality in chronic granulomatous disease.

1980 • 203 citations

Activity and activation of the granulocyte superoxide-generating system

1980 • 199 citations

Correlation between membrane potential changes and superoxide production in human granulocytes stimulated by phorbol myristate acetate. Evidence for defective activation in chronic granulomatous disease.

1980 • 198 citations

ABSENCE OF A NEWLY DESCRIBED CYTOCHROME b FROM NEUTROPHILS OF PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE

1978 • 197 citations

Fat Metabolism in Higher Plants

1967 • 178 citations

Superoxide-forming enzyme from human neutrophils: evidence for a flavin requirement

1977 • 174 citations

The subcellular distribution and some properties of the cytochrome b component of the microbicidal oxidase system of human neutrophils

1979 • 145 citations

Arrangement of the respiratory burst oxidase in the plasma membrane of the neutrophil.

1981 • 133 citations

NAD(P)H oxidase activity in human neutrophils stimulated by phorbol myristate acetate.

1980 • 122 citations

Absence of cytochrome b reduction in stimulated neutrophils from both female and male patients with chronic granulomatous disease

1980 • 117 citations

Functional relationship of the cytochrome b to the superoxide-generating oxidase of human neutrophils.

1982 • 109 citations

A Variant of Chronic Granulomatous Disease: Deficient Oxidative Metabolism Due to a Low-Affinity NADPH Oxidase

1981 • 106 citations

Kinetics of oxygen consumption by phagocytosing human neutrophils

1978 • 103 citations

Comparative study of the metabolic and bactericidal characteristics of severely glucose-6-phosphate dehydrogenase-deficient polymorphonuclear leukocytes and leukocytes from children with chronic granulomatous disease.

1972 • 97 citations

Anthranilate Synthetase, an Enzyme Specified by the Tryptophan Operon of Escherichia coli : Comparative Studies on the Complex and the Subunits

1969 • 93 citations

Defective Initiation of Oxidative Metabolism in Polymorphonuclear Leukocytes

1979 • 89 citations

Reduction and subsequent oxidation of a cytochrome b of human neutrophils after stimulation with phorbol myristate acetate

1979 • 88 citations

Defective initiation of the metabolic stimulation in phagocytizing granulocytes: a new congenital defect.

1976 • 62 citations

Isolation of plasma membrane from human neutrophils and determination of cytochrome b and quinone content

1981 • 61 citations

CYTOCHROME b IS PRESENT IN NEUTROPHILS FROM PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE

1979 • 43 citations

Rapid kinetic studies of partial reactions in the heme free derivative of L-lactate cytochrome c oxidoreductase (flavocytochrome b₂); the flavodehydrogenase function

1977 • 41 citations

Rapid incorporation of the human neutrophil plasma membrane cytochrome b into phagocytic vacuoles

1980 • 40 citations

Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line.

1980 • 27 citations

Reduced Nicotinamide Adenine Dinucleotide and Reduced Nicotinamide Adenine Dinucleotide Phosphate Diaphorase Activity in Human Polymorphonuclear Leukocytes

1974 • 26 citations