The Molecular Epidemiology of Nosocomial Infection

Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing

1995 • 8,278 citations

Distribution of repetitive DNA sequences in eubacteria and application to finerpriting of bacterial enomes

1991 • 3,175 citations

Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology

1993 • 2,362 citations

A highly conserved repeated DNA element located in the chromosome ofStreptococcus pneumoniae

1992 • 381 citations

Laboratory investigation of a multistate food-borne outbreak of Escherichia coli O157:H7 by using pulsed-field gel electrophoresis and phage typing

1994 • 361 citations

Outbreak of vancomycin-, ampicillin-, and aminoglycoside-resistant Enterococcus faecium bacteremia in an adult oncology unit

1994 • 332 citations

Factors affecting reliability and reproducibility of amplification-based DNA fingerprinting of representative bacterial pathogens

1997 • 290 citations

New Techniques for Purifying Large DNAs and Studying Their Properties and Packaging

1983 • 274 citations

Ceftazidime-Resistant Klebsiella pneumoniae and Escherichia coli Bloodstream Infection: A Case-Control and Molecular Epidemiologic Investigation

1996 • 264 citations

Global Genetic Structure and Molecular Epidemiology of Encapsulated Haemophilus influenzae

1990 • 232 citations

Pulsed-field gel electrophoresis of NotI digests of leptospiral DNA: a new rapid method of serovar identification

1992 • 171 citations

Genotypic characterization of five subspecies of Mycobacterium kansasii

1997 • 164 citations

International epidemiological and microbiological study of outbreak of Salmonella agona infection from a ready to eat savoury snack--I: England and Wales and the United States

1996 • 160 citations

Molecular Epidemiology of Nosocomial Infection: Analysis of Chromosomal Restriction Fragment Patterns by Pulsed-Field Gel Electrophoresis

1993 • 154 citations

Inter- and intraspecies identification of Bartonella (Rochalimaea) species

1995 • 142 citations

Competition as a source of errors in RAPD analysis

1996 • 142 citations

Use of low-frequency-cleavage restriction endonucleases for DNA analysis in epidemiological investigations of nosocomial bacterial infections

1989 • 140 citations

Clinical and Molecular Epidemiology of Vancomycin-Resistant Enterococcus faecium During Its Emergence in a City in Southern Texas

1995 • 134 citations

Electrophoretic karyotyping as a taxonomic tool in the genusSaccharomyces

1993 • 125 citations

Comparison of ribotyping and pulsed-field gel electrophoresis for molecular typing of Acinetobacter isolates

1995 • 125 citations

Comparison of Pulsed-Field Gel Electrophoresis, Ribotyping, and Plasmid Profiling for Typing of Vibrio anguillarum Serovar O1

1995 • 122 citations

Pulsed-Field Gel Electrophoresis of Campylobacter jejuni and Campylobacter coli Genomic DNA and Its Epidemiologic Application

1991 • 117 citations

Novel BOX repeat PCR assay for high-resolution typing of Streptococcus pneumoniae strains

1996 • 117 citations

Use of pulsed-field gel electrophoresis typing to study an outbreak of infection due to Serratia marcescens in a neonatal intensive care unit

1996 • 116 citations

Genetic relatedness within and between serotypes of Streptococcus pneumoniae from the United Kingdom: analysis of multilocus enzyme electrophoresis, pulsed-field gel electrophoresis, and antimicrobial resistance patterns

1996 • 112 citations

The XbaI-BlnI-CeuI genomic cleavage map of Salmonella typhimurium LT2 determined by double digestion, end labelling, and pulsed-field gel electrophoresis

1993 • 111 citations

Analysis of clonal relationships among isolates of Shigella sonnei by different molecular typing methods

1995 • 110 citations

Comparison of restriction endonuclease analysis, ribotyping, and pulsed-field gel electrophoresis for molecular differentiation of Clostridium difficile strains

1994 • 109 citations

Three species of Borrelia burgdorferi sensu lato (B. burgdorferi sensu stricto, B afzelii, and B. garinii) identified from cerebrospinal fluid isolates by pulsed-field gel electrophoresis and PCR

1996 • 108 citations

Nosocomial Outbreak Caused by a Multiresistant Clone of Acinetobacter baumannii: Results of the Case-Control and Molecular Epidemiologic Investigations

1995 • 107 citations

Molecular epidemiology of Corynebacterium diphtheriae from northwestern Russia and surrounding countries studied by using ribotyping and pulsed-field gel electrophoresis

1995 • 106 citations

Determination of genome size, macrorestriction pattern polymorphism, and nonpigmentation-specific deletion in Yersinia pestis by pulsed-field gel electrophoresis

1992 • 104 citations

Karyotype instability in Cryptococcus neoformans infection

1996 • 104 citations

Molecular epidemiology of Xanthomonas maltophilia colonization and infection in the hospital environment

1995 • 104 citations

Endemic Nosocomial Transmission of Staphylococcus epidermidis Bacteremia Isolates in a Neonatal Intensive Care Unit over 1O Years

1994 • 103 citations

Physical and genetic mapping of the genomes of five Mycoplasma hominis strains by pulsed-field gel electrophoresis

1992 • 98 citations

Comparison of ribotyping, arbitrarily primed PCR, and pulsed-field gel electrophoresis for molecular typing of Listeria monocytogenes

1996 • 97 citations

DNA large restriction fragment patterns of sporadic and epidemic nosocomial strains of Mycobacterium chelonae and Mycobacterium abscessus

1993 • 96 citations

Molecular epidemiology of Klebsiella pneumoniae producing SHV-5 beta- lactamase: parallel outbreaks due to multiple plasmid transfer

1996 • 94 citations

Molecular epidemiology of an outbreak of multidrug-resistant Enterobacter aerogenes infections and in vivo emergence of imipenem resistance

1997 • 93 citations

Efficient subtyping of pathogenic Yersinia enterocolitica strains by pulsed-field gel electrophoresis

1994 • 93 citations

Mycobacterium abscessus Pseudoinfection Traced to an Automated Endoscope Washer: Utility of Epidemiologic and Laboratory Investigation

1994 • 90 citations

Analysis of Salmonella typhi isolates from Southeast Asia by pulsed-field gel electrophoresis

1995 • 89 citations

Comparison of ribotyping and pulsed-field gel electrophoresis for subspecies differentiation of strains of Enterococcus faecalis

1993 • 89 citations

Strain delineation and antifungal susceptibilities of epidemiologically related and unrelated isolates of Candida lusitaniae

1994 • 88 citations

A physical genome map of the Burkholderia cepacia type strain

1995 • 88 citations

Genome maps of Campylobacter jejuni and Campylobacter coli

1992 • 88 citations

Use of Pulsed Field Gel Electrophoresis to Differentiate Coxiella burnetii Strainsa

1990 • 88 citations

Molecular typing of Cryptococcus neoformans serotype D clinical isolates

1994 • 86 citations

Epidemiological fingerprinting of Enterobacter cloacae by small-fragment restriction endonuclease analysis and pulsed-field gel electrophoresis of genomic restriction fragments

1993 • 85 citations

Molecular Epidemiology of Nosocomial Infection: Analysis of Chromosomal Restriction Fragment Patterns by Pulsed-Field Gel Electrophoresis

1993 • 84 citations

Pulsed-field gel electrophoresis and ribotype profiles of clinical and environmental Vibrio vulnificus isolates

1996 • 84 citations

Multiple Vibrio vulnificus strains in oysters as demonstrated by clamped homogeneous electric field gel electrophoresis

1995 • 83 citations

Polyclonal infections due to Mycobacterium avium complex in patients with AIDS detected by pulsed-field gel electrophoresis of sequential clinical isolates

1994 • 81 citations

Genome mapping ofClostridium perfringens strains with I-CeuI shows many virulence genes to be plasmid-borne

1996 • 81 citations

Typing of group B streptococci: comparison of pulsed-field gel electrophoresis and conventional electrophoresis

1993 • 79 citations

DNA polymorphism in Mycobacterium paratuberculosis, "wood pigeon mycobacteria," and related mycobacteria analyzed by field inversion gel electrophoresis

1989 • 79 citations

Insertion and excision of Bacteroides conjugative chromosomal elements

1992 • 77 citations

Comparison of Legionella pneumophila isolates by arbitrarily primed PCR and pulsed-field gel electrophoresis: analysis from seven epidemic investigations

1995 • 77 citations

Application of typing by pulsed-field gel electrophoresis to the study of Clostridium difficile in a neonatal intensive care unit

1994 • 77 citations

Comparison of restriction enzyme analysis versus pulsed-field gradient gel electrophoresis as a typing system for Torulopsis glabrata and Candida species other than C. albicans

1993 • 76 citations

Persistence of Staphylococcus aureus strains among cystic fibrosis patients over extended periods of time

1996 • 76 citations

Investigation of a Multiyear Multiple Critical Care Unit Outbreak Due to Relatively Drug-Sensitive Acinetobacter baumannii: Risk Factors and Attributable Mortality

1996 • 76 citations

Comparison of three molecular methods for typing and subtyping pathogenic Yersinia enterocolitica strains

1996 • 74 citations

International epidemiological and microbiological study of outbreak of Salmonella agona infection from a ready to eat savoury snack--II: Israel

1996 • 73 citations

Evaluation of DNA Fingerprinting by PFGE as an Epidemiologic Tool for Salmonella Infections

1995 • 73 citations

Variations in DNA subtype, antifungal susceptibility, and slime production among clinical isolates of Candida parapsilosis

1995 • 72 citations

Comparison of Pulsed-Field Gel Electrophoresis with Isoenzyme Profiles as a Typing System for Candida tropicalis

1993 • 71 citations

Single and Multiple Strain Colonization in Patients with Helicobacter pylori Associated Gastritis: Detection by Macrorestriction DNA Analysis

1994 • 71 citations

Genome analysis of Clostridium botulinum type A by pulsed-field gel electrophoresis

1995 • 69 citations

Evaluation of the molecular epidemiology of an outbreak of multiply resistant Shigella sonnei in a day-care center by using pulsed-field gel electrophoresis and plasmid DNA analysis

1993 • 66 citations

Epidemiologic Typing Systems

1996 • 66 citations

Molecular typing of Salmonella enterica serovar typhi

1996 • 63 citations

Molecular analysis of isolates of Salmonella typhi obtained from patients with fatal and nonfatal typhoid fever

1996 • 62 citations

XbaI and BlnI Genomic Cleavage Maps of Escherichia coli K-12 Strain MG1655 and Comparative Analysis of Other Strains

1993 • 60 citations

Comparative evaluation of molecular typing of strains from a national epidemic due to Salmonella brandenburg by rRNA gene and IS200 probes and pulsed-field gel electrophoresis

1994 • 60 citations

Molecular Subtyping Of Toxigenic Vibrio Cholerae O139 Causing Epidemic Cholera In India And Bangladesh, 1992-1993

1995 • 60 citations

Analysis of Enterococcus faecalis isolates from intercontinental sources by multilocus enzyme electrophoresis and pulsed-field gel electrophoresis

1995 • 59 citations

Subspecies typing of Vibrio parahaemolyticus by pulsed-field gel electrophoresis

1996 • 59 citations

Molecular epidemiology ofBurkholderia cepacia, Stenotrophomonas maltophilia, andAlcaligenes xylosoxidans in a cystic fibrosis center

1996 • 58 citations

Genomic analysis of Mycobacterium bovis and other members of the Mycobacterium tuberculosis complex by isoenzyme analysis and pulsed-field gel electrophoresis

1996 • 58 citations

Molecular analysis of multiple isolates of the major serotypes of group B streptococci

1993 • 57 citations

Pulsed‐field gel electrophoresis as an epidemiological tool for clonal identification of Aeromonas hydrophila

1996 • 55 citations

In vitro susceptibility testing and DNA typing of Saccharomyces cerevisiae clinical isolates

1996 • 55 citations

Molecular epidemiology of Escherichia coli O157:H7 by pulsed-field gel electrophoresis and comparison with that by bacteriophage typing

1996 • 54 citations

Restriction fragment length polymorphisms distinguish Leptospira borgpetersenii serovar hardjo type hardjo-bovis isolates from different geographical locations

1993 • 53 citations

Construction of physical and genetic maps of Chlamydia trachomatis serovar L2 by pulsed-field gel electrophoresis

1992 • 53 citations

Use of pulsed-field gel electrophoresis to investigate an outbreak of Serratia marcescens

1997 • 52 citations

The Emerging Diversity of the Electrophoretic Types of Vibrio cholerae in the Western Hemisphere

1995 • 51 citations

Physical analysis and mapping of the Mycoplasma pneumoniae chromosome

1990 • 49 citations

Molecular epidemiology of fluoroquinolone-resistant Escherichia coli bloodstream isolates from patients admitted to European cancer centers

1996 • 49 citations

Pulsed-field gel electrophoresis analysis of the genome of amino acid producing corynebacteria: chromosome sizes and diversity of restriction patterns

1994 • 47 citations

Evaluation and comparison of molecular techniques for epidemiological typing of Salmonella enterica subsp. enterica serovar dublin

1996 • 47 citations

Molecular epidemiology provides evidence of genotypic heterogeneity of multidrug-resistant Pseudomonas aeruginosa serotype O:12 outbreak isolates from a pediatric hospital

1996 • 46 citations

Epidemiologic Typing Systems

1996 • 44 citations

Nosocomial infection by Staphylococcus haemolyticus and typing methods for epidemiological study

1994 • 44 citations

Campylobacter fetus diarrhea in a Hutterite colony: epidemiological observations and typing of the causative organism

1994 • 44 citations

Wide diversity of genome size among different strains of Clostridium acetobutylicum

1993 • 43 citations

Comparison of four DNA-based methods for strain delineation of Candida lusitaniae

1995 • 43 citations

Characterization of chromosomal DNA profiles from Helicobacter pylori strains isolated from sequential gastric biopsy specimens

1995 • 42 citations

Genotyping of outbreak-related and sporadic isolates of Clostridium difficile belonging to serogroup C

1996 • 42 citations

Analysis of Bordetella pertussis isolates from an epidemic by pulsed-field gel electrophoresis

1995 • 42 citations

Evaluation of ribotyping as epidemiologic tool for typing Escherichia coli serogroup O157 isolates

1996 • 40 citations

Novel Borrelia burgdorferi isolates from Ixodes scapularis and Ixodes dentatus ticks feeding on humans

1996 • 40 citations

Transmission of Fluconazole-Resistant Candida albicans Between Patients with AIDS and Oropharyngeal Candidiasis Documented by Pulsed-Field Gel Electrophoresis

1995 • 40 citations

Epidemiological typing of isolates from an outbreak of infection with multidrug-resistant Enterobacter cloacae by repetitive extragenic palindromic unit b1-primed PCR and pulsed-field gel electrophoresis

1996 • 39 citations

High-Resolution Genotyping Elucidates the Epidemiology of Group A Streptococcus Outbreaks

1996 • 39 citations

Comparison of PCR-based approaches to molecular epidemiologic analysis of Clostridium difficile

1996 • 36 citations

Determination of genome size and restriction pattern polymorphism ofRickettsia prowazekiiandRickettsia typhiby pulsed field gel electrophoresis

1993 • 34 citations

Neisseria meningitidis with decreased susceptibility to penicillin in Saskatchewan, Canada

1995 • 34 citations

Pulsed-Field Gel Electrophoresis as a Method of Biotyping of Giardia duodenalis

1993 • 34 citations

A molecular karyotype of Eimeria tenella as revealed by contour-clamped homogeneous electric field gel electrophoresis

1990 • 34 citations

Differentiation between human and ovine isolates ofBordetellaparapertussisusing pulsed-field gel electrophoresis

1996 • 32 citations

Evaluation of pulsed-field gel electrophoresis as a typing system for Candida rugosa: comparison of karyotype and restriction fragment length polymorphisms

1996 • 32 citations

Evaluation of the relatedness of strains ofMycobacterium avium using pulsed-field gel electrophoresis

1995 • 32 citations

Molecular epidemiology of Streptococcus pneumoniae with decreased susceptibility to penicillin in a Paris children's hospital

1997 • 30 citations

The size and a physical map of the chromosome of Haemophilus parainfluenzae

1989 • 30 citations

Comparative DNA analysis of Bordetella pertussis clinical isolates by pulsed-field gel electrophoresis, randomly amplified polymorphism DNA, and ERIC polymerase chain reaction

1996 • 29 citations

Consensus guidelines for appropriate use and evaluation of microbial epidemiologic typing systems

1996 • 29 citations

Comparison of arbitrarily-primed polymerase chain reaction, restriction enzyme analysis and pulsed-field gel electrophoresis for typing Clostridium difficile

1996 • 29 citations

Plasmid characterization and pulsed‐field electrophoretic analysis demonstrate that ampicillin‐resistant strains of Salmonella enteritidis phage type 6a are derived from Salm. enteritidis phage type 4

1996 • 28 citations

An Epidemiological Study of Salmonella enteritidis by Pulsed‐Field Gel Electrophoresis (PFGE): Several PFGE Patterns Observed in Isolates from a Food Poisoning Outbreak

1996 • 28 citations

Relapse of Catheter-Related Flavobacterium meningosepticum Bacteremia Demonstrated by DNA Macrorestriction Analysis

1995 • 27 citations

Genomic study of Rickettsia akari by pulsed-field gel electrophoresis

1995 • 27 citations

Transmission of Citrobacter koseri from mother to infant documented by ribotyping and pulsed-field gel electrophoresis

1996 • 27 citations

Karyotype variability in Trypanosoma rangeli

1996 • 26 citations

A new protein kinase, SSP31, modulating the SMP3 gene-product involved in plasmid maintenance in Saccharomyces cerevisiae

1991 • 26 citations

Differentiation of Neisseria gonorrhoeae isolates requiring proline, citrulline, and uracil by plasmid content, serotyping, and pulsed-field gel electrophoresis

1995 • 25 citations

Epidemiological evaluation ofNeisseria meningitidisserogroup B by pulsed-field gel electrophoresis

1995 • 25 citations

Molecular typing of multi-drug resistant Shigella dysenteriae type 1 by plasmid analysis and pulsed-field gel electrophoresis

1996 • 25 citations

Genome conservation inHelicobacter mustelaeas determined by pulsed-field gel electrophoresis

1994 • 24 citations

Use of Restriction Endonuclease Analysis of Plasmids and Pulsed-Field Gel Electrophoresis to Investigate Outbreaks of Methicillin-Resistant Staphylococcus aureus Infection

1996 • 24 citations

Electrophoretic karyotype and chromosome assignments for a pathogenic and a nonpathogenic strain of Entamoeba histolytica

1993 • 24 citations

A spontaneous 99-kb chromosomal deletion results in multi-antibiotic susceptibility and an attenuation of contact haemolysis in Shigella flexneri 2a

1996 • 23 citations

An Outbreak of Fatal Nosocomial Infections Due to Group A Streptococcus on a Medical Ward

1996 • 23 citations

Pulsed-field gel electrophoresis indicates genotypic heterogeneity amongCampylobacter upsaliensisstrains

1996 • 23 citations

Subtyping Listeria monocytogenes isolates genetically related to the Swiss epidemic clone

1996 • 22 citations

Restriction Fragment Length Polymorphism (RFLP) of Genomic DNA of Moraxella (Branhamella) catarrhalis Isolates in a Hospital

1994 • 22 citations

Correlation of SfiI macrorestriction endonuclease fingerprint analysis of Candida parapsilosis isolates with source of isolation

1996 • 22 citations

DNA polymorphisms detected in Mycobacterium haemophilum by pulsed-field gel electrophoresis

1994 • 22 citations

Role of bacteriophages in genomic variability of related coagulase-negative staphylococci

1993 • 22 citations

Pulsed field gel electrophoresis of representatives ofMycobacterium tuberculosisandMycobacterium bovisBCG strains

1992 • 21 citations

Analysis by pulsed-field gel electrophoresis of insertion mutations in the transferrin-binding system of Haemophilus influenzae type b

1994 • 21 citations

Genome macrorestriction analysis of sequential Pseudomonas aeruginosa isolates from bronchiectasis patients without cystic fibrosis

1996 • 21 citations

Biochemical, Immunological, and Biological Characterization of Trypanosoma cruzi Populations of the Andean North of Chile

1995 • 21 citations

Evaluation of pulsed-field gel electrophoresis and rep-PCR for the epidemiological analysis ofOchrobactrum anthropi strains

1995 • 20 citations

Chromosomal DNA restriction endonuclease digestion patterns of beta-lactamase-producing Enterococcus faecalis isolates collected from a single hospital over a 7-year period

1996 • 20 citations

Discriminatory genomic fingerprinting of Legionella pneumophila by pulsed-field electrophoresis

1994 • 20 citations

DNA fingerprinting by pulsed-field gel electrophoresis to investigate a nosocomial pneumonia caused by Legionella bozemanii serogroup 1

1995 • 20 citations

Karyotyping by PFGE of clinical isolates ofSporothrix schenckii

1996 • 19 citations

GENOMIC FINGERPRINTING BY PULSED FIELD GEL ELECTROPHORESIS TO IDENTIFY THE SOURCE OF PASTEURELLA MULTOCIDA SEPSIS

1996 • 18 citations

Construction of a Combined NotI/SmaI Physical and Genetic Map of Moraxella (Branhamella) catarrhalis Strain ATCC25238

1995 • 18 citations

Localization of prophages of serological group B and F on restriction fragments defined in the restriction map of Staphylococcus aureus NCTC 8325

1996 • 18 citations

DNA macrorestriction profiles and antifungal susceptibility of Candida (Torulopsis) glabrata

1996 • 17 citations

Lack of evidence of nosocomial cross-infection byBurkholderia cepacia among danish cystic fibrosis patients

1996 • 16 citations

Genetic variability among Chlamydia trachomatis reference and clinical strains analyzed by pulsed-field gel electrophoresis

1994 • 12 citations

An Outbreak of Fatal Nosocomial Infections Due to Group A Streptococcus on a Medical Ward

1996 • 11 citations

Chronic bacteraemia due to Staphylococcus epidermidis after bone marrow transplantation

1995 • 11 citations

Chromosomal localization of 20 genes to five distinct pulsed field gel karyotypic forms of rat Pneumocystis carinii.

1994 • 9 citations

Nosocomial Transmission of Serratia odorifera Biogroup 2: Case Report Demonstration by Macrorestriction Analysis of Chromosomal DNA Using Pulsed-Field Gel Electrophoresis

1994 • 8 citations

A single strain of Candida albicans associated with separate episodes of fungemia and meningitis

1996 • 7 citations

Karyotype studies on different strains of Candida molischiana by pulsed-field gel electrophoresis

1995 • 7 citations

Nosocomial Transmission of Serratia odorifera Biogroup 2: Case Report Demonstration by Macrorestriction Analysis of Chromosomal DNA Using Pulsed-Field Gel Electrophoresis

1994 • 5 citations

Plasmid characterization and pulsed-field electrophoretic analysis demonstrate that ampicillin-resistant strains of Salmonella enteritidis phage type 6a are derived from Salm. enteritidis phage type 4

1996 • 2 citations

Deleted Work

1955 • 0 citations