Nucleic Acid Hybridization for the Detection of Viral Genomes

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature

1962 • 4,132 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Repeated Sequences in DNA

1968 • 2,836 citations

A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane

1965 • 1,981 citations

Kinetics of renaturation of DNA

1968 • 1,446 citations

Epstein–Barr Virus in Burkitt's Lymphoma and Nasopharyngeal Carcinoma: EBV DNA in Biopsies of Burkitt Tumours and Anaplastic Carcinomas of the Nasopharynx

1970 • 1,261 citations

Characterization of EBV‐genome negative “null” and “T” cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non‐Hodgkin lymphoma

1977 • 698 citations

Dependence of the melting temperature of DNA on salt concentration

1965 • 688 citations

Epstein‐barr virus‐specific IgA serum antibodies as an outstanding feature of nasopharyngeal carcinoma

1976 • 644 citations

Nucleic acid reassociation in formamide

1969 • 602 citations

Hybridization of RNA to double-stranded DNA: formation of R-loops.

1976 • 443 citations

[38] Nucleic acid hybridization in cytological preparations

1971 • 368 citations

A rapid method for detecting and mapping homology between heterologous DNAs. Evaluation of polyomavirus genomes.

1979 • 340 citations

Quantitation of simian virus 40 sequences in African green monkey, mouse and virus-transformed cell genomes

1971 • 292 citations

Relationship between Epstein‐Barr virus (EBV) DNA and the EBV‐determined nuclear antigen (EBNA) in Burkitt lymphoma biopsies and other lymphoproliferative malignancies

1974 • 267 citations

DNA of Epstein-Barr Virus Detected in Tissue of Burkitt's Lymphoma and Nasopharyngeal Carcinoma

1973 • 231 citations

Nucleic acid spot hybridization: rapid quantitative screening of lymphoid cell lines for Epstein-Barr viral DNA.

1980 • 211 citations

Comparison of Epstein-Barr virus strains of different origin by analysis of the viral DNAs

1980 • 149 citations

The structure of the termini of the DNA of Epstein-Barr virus

1979 • 109 citations

DNA of Epstein-Barr virus. IV. Linkage map of restriction enzyme fragments of the B95-8 and W91 strains of Epstein-Barr Virus

1978 • 100 citations

Attempts to demonstrate virus‐specific sequences in human tumors. IV. EB viral DNA in European burkitt lymphoma and immunoblastic lymphadenopathy with excessive plasmacytosis

1976 • 94 citations

Conserved polynucleotide sequences among the genomes of papillomaviruses

1979 • 93 citations

DNA of Epstein-Barr virus. V. Direct repeats of the ends of Epstein-Barr virus DNA

1979 • 92 citations

Association of Epstein–Barr viral genomes with American Burkitt lymphoma

1976 • 88 citations

DNA base sequence homology between coliphages T7 and øII and between T3 and øII as determined by heteroduplex mapping in the electron microscope

1973 • 87 citations

Elevated IgA in carcinoma of the nasopharynx

1975 • 82 citations

The Detection of DNA Tumour Virus-specific RNA Sequences in Abnormal Human Cervical Biopsies by in situ Hybridization

1981 • 72 citations

Association of Epstein‐Barr virus with nasopharyngeal carcinoma in alaskan native patients: Serum antibodies and tissue EBNA and DNA

1981 • 71 citations

Biological and biochemical observations on isolates of EB virus from the malignant epithelial cells of two nasopharyngeal carcinomas

1979 • 70 citations

DNA of Epstein-Barr virus. VI. Mapping of the internal tandem reiteration

1979 • 70 citations

Cleavage of Epstein-Barr virus DNA by restriction endonucleases EcoRI, HindIII and BamI

1978 • 69 citations

Detection of RNA complementary to herpes simplex virus DNA in human cervical squamous cell neoplasms.

1981 • 68 citations

Epstein-Barr virus-positive Burkitt's lymphoma in a german woman during pregnancy

1980 • 64 citations

Organization of repeated regions within the Epstein-Barr virus DNA molecule

1980 • 50 citations

A Cluster of Epstein-Barr-Virus-Associated American Burkitt's Lymphoma

1977 • 45 citations

Detection of Epstein‐Barr viral DNA internal repeats in the nasopharyngeal mucosa of chinese with IgA/ebv‐specific antibodies

1982 • 36 citations

Comparison of Epstein-Barr viral DNAs in Burkitt lymphoma biopsy cells and in cells clonally transformed in vitro.

1977 • 35 citations

An immunologic basis for detection of occult primary malignancies of the head and neck

1978 • 28 citations

Differentiation ofHerpes Simplex virus serotypes 1 and 2 by DNA-DNA-hybridization

1975 • 10 citations