Immunology of the Nicotinic Acetylcholine Receptor

Antibody to acetylcholine receptor in myasthenia gravis

1998 • 1,149 citations

Autoimmune Response to Acetylcholine Receptor

1973 • 1,019 citations

Neuromuscular Junction in Myasthenia Gravis: Decreased Acetylcholine Receptors

1973 • 633 citations

Myasthenia Gravis: A New Hypothesis

1960 • 585 citations

Chemical and Molecular Basis of Nerve Activity

1975 • 480 citations

Chemistry and Pharmacology of Polypeptide Toxins in Snake Venoms

1972 • 479 citations

Myasthenia Gravis

1977 • 428 citations

Plasmapheresis and Immunosuppressive Drug Therapy in Myasthenia Gravis

1977 • 396 citations

REMISSION OF MYASTHENIA GRAVIS FOLLOWING PLASMA-EXCHANGE

1976 • 392 citations

Experimental autoimmune myasthenia: A model of myasthenia gravis in rats and guinea pigs.

1975 • 325 citations

REGULATION OF THE IMMUNE RESPONSE

1969 • 315 citations

Function of circulating antibody to acetylcholine receptor in myasthenia gravis

1978 • 275 citations

Myasthenic Immunoglobulin Accelerates Acetylcholine Receptor Degradation

1977 • 260 citations

Changes in Serum Complement Activity in Patients with Myasthenia Gravis.

1960 • 247 citations

Thymic Muscle Cells Bear Acetylcholine Receptors: Possible Relation to Myasthenia Gravis

1977 • 244 citations

Role of complement in the pathogenesis of experimental autoimmune myasthenia gravis.

1978 • 239 citations

Pathological mechanisms in experimental autoimmune myasthenia gravis. II. Passive transfer of experimental autoimmune myasthenia gravis in rats with anti-acetylcholine recepotr antibodies.

1976 • 218 citations

Modulation of acetylcholine receptor by antibody against the receptor

1977 • 201 citations

Immunological distinction between acetylcholine receptor and the alpha-bungarotoxin-binding component on sympathetic neurons.

1977 • 199 citations

Acetylcholine Receptor Antibodies in Myasthenia Gravis

1975 • 192 citations

Gradually Increasing Doses of Prednisone in Myasthenia Gravis

1974 • 186 citations

MYASTHENIA GRAVIS: A SERUM FACTOR BLOCKING ACETYLCHOLINE RECEPTORS OF THE HUMAN NEUROMUSCULAR JUNCTION

1975 • 185 citations

EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS: CELLULAR AND HUMORAL IMMUNE RESPONSES*

1976 • 185 citations

Pathological mechanisms in experimental autoimmune myasthenia gravis. I. Immunogenicity of syngeneic muscle acetylcholine receptor and quantitative extraction of receptor and antibody-receptor complexes from muscles of rats with experimental automimmune myasthenia gravis.

1976 • 175 citations

THE MOTOR END PLATE IN MYASTHENIA GRAVIS AND IN EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS. A QUANTITATIVE ULTRASTRUCTURAL STUDY*

1976 • 168 citations

Purification fromTorpedo marmorata electric tissue of membrane fragments particularly rich in cholinergic receptor protein

1972 • 160 citations

Characterization of Torpedo californica Acetylcholine Receptor: Its Subunit Composition and Ligand-binding Properties

1976 • 153 citations

Accelerated degradation of acetylcholine receptor from cultured rat myotubes with myasthenia gravis sera and globulins.

1977 • 150 citations

HUMORAL ANTIBODIES TO ACETYLCHOLINE RECEPTOR IN PATIENTS WITH MYASTHENIA GRAVIS

1975 • 148 citations

Facets of the Structures of Acetylcholine Receptors from Electrophorus and Torpedo

1976 • 142 citations

Immunization of rats with polypeptide chains from torpedo acetylcholine receptor causes an autoimmune response to receptors in rat muscle.

1978 • 140 citations

Regulation of the immune response. I. Suppression of delayed‐type hypersensitivity by T cells from mice expressing humoral immunity

1976 • 136 citations

Strain differences in the autoimmune response of mice to acetylcholine receptors

1976 • 130 citations

Immunochemical studies on acetylcholine receptor from Torpedo californica

1977 • 130 citations

Striated muscle fibres differentiate in monolayer cultures of adult thymus reticulum

1975 • 120 citations

INTRATHYMIC PATHOGENESIS AND DUAL GENETIC CONTROL OF MYASTHENIA GRAVIS

1977 • 120 citations

Benefit from Alternate-Day Prednisone in Myasthenia Gravis

1972 • 119 citations

Cellular Immunity in Myasthenia Gravis

1976 • 117 citations

Immunological characterisation of the cholinergic receptor protein from Electrophorus electricus

1973 • 113 citations

Experimental autoimmune myasthenia induced in monkeys by purified acetylcholine receptor

1975 • 106 citations

Cellular immune response to acetylcholine receptor-rich fraction, in patients with myasthenia gravis.

1975 • 98 citations

Immunological comparison of acetylcholine receptors and their subunits from species of electric ray

1977 • 89 citations

Human myasthenic sera reduce acetylcholine sensitivity of human muscle cells in tissue culture

1977 • 87 citations

THE THYMUS AND NEUROMUSCULAR FUNCTION

1968 • 86 citations

Synthesis of acetylcholine receptor by denervated rat diaphragm muscle.

1975 • 82 citations

Appearance and disappearance of acetycholine receptor during differentiation of chick skeletal muscle in vitro

1976 • 78 citations

Neuromuscular transmission after immunization against acetylcholine receptors

1975 • 76 citations

Induction of anti-idiotypic antibodies by immunisation with syngeneic spleen cells educated with acetylcholine receptor

1978 • 75 citations

Regulation of the immune response II. Repressor T cells in cyclophosphamide‐induced tolerant mice

1977 • 72 citations

An immunological approach to the structural relationship between hen egg-white lysozyme and bovine α-lactalbumin

1971 • 71 citations

EFFECTS OF SOME IMMUNOSUPPRESSIVE PROCEDURES ON MYASTHENIA GRAVIS*

1976 • 70 citations

TREATMENT OF MYASTHENIA GRAVIS WITH PREDNISONE

1972 • 63 citations

Specific immunosuppression of experimental autoimmune myasthenia gravis by denatured acetylcholine receptor.

1978 • 60 citations

Immunological relationship between acetylcholine receptor and thymus: a possible significance in myasthenia gravis.

1975 • 59 citations

HL‐A ANTIGENS, AUTOANTIBODY PRODUCTION, AND ASSOCIATED DISEASES IN THYMOMA PATIENTS, WITH AND WITHOUT MYASTHENIA GRAVIS

1976 • 52 citations

Immunological characterization of an irreversibly denatured acetylcholine receptor

1977 • 51 citations

Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs.

1975 • 51 citations

Localization of acetylcholine receptor in excitable membrane from the electric organ of Torpedo: Evidence for exposure of receptor antigenic sites on both sides of the membrane.

1978 • 49 citations

Myasthenia Gravis and Acetylcholine Receptor

1975 • 49 citations

Neurophysiological signs of myasthenia in rabbits after receptor antibody development

1975 • 48 citations

Experimental myasthenia in Balb/c mice immunized with rat acetylcholine receptor from rat denervated muscle.

1976 • 48 citations

Synthesis of acetylcholine receptor during differentiation of cultured embryonic muscle cells.

1975 • 47 citations

ANTIBODIES TO ACETYLCHOLINE RECEPTORS IN RABBITS: IMMUNOCHEMICAL AND ELECTROPHYSIOLOGICAL STUDIES*

1976 • 47 citations

Comparative study of cyclophosphamide, 6-mercaptopurine, azathiopurine and methotrexate. Relative effects on the humoral and the cellular immune response in the mouse.

1976 • 46 citations

Myasthenia gravis serum reduces acetylcholine sensitivity in cultured rat myotubes

1977 • 46 citations

Studies on experimental autoimmune thymitis in guinea-pigs.

1969 • 42 citations

Isolation and Purification of the Nicotinic Acetylcholine Receptor and Its Functional Reconstitution into a Membrane Environment

1977 • 37 citations

Reduced muscle acetylcholine sensitivity in rats immunised with acetylcholine receptor

1976 • 37 citations

Preparation and immunochemical characterization of a water-soluble acetylcholine receptor fraction from the electric organ tissue of the electric eel

1975 • 35 citations

The Cholinergic Receptor Protein from Fish Electric Organ

1975 • 31 citations

Radioimmunoassay of antibodies to acetylcholine receptor in serum of myasthenia gravis patients.

1978 • 31 citations

Immunosuppression of Experimental Autoimmune Myasthenia Gravis by Hydrocortisone and Azathioprine

1976 • 28 citations

THE BIOLOGIC SIGNIFICANCE OF HL‐A ANTIGEN MARKERS IN MYASTHENIA GRAVIS*

1976 • 28 citations

Ligand induced changes in stability and distribution of acetylcholine receptors on surface membranes of muscle cells

1979 • 24 citations

Study of two different subpopulations of anti‐acetylcholine receptor antibodies in a rabbit with experimental autoimmune myasthenia gravis

1977 • 24 citations

ON THE SIGNIFICANCE OF HL-A AND LD ANTIGENS IN MYASTHENIA GRAVIS*

1976 • 23 citations

Cytophilic Antibodies in Experimental Autoimmune Myasthenia Gravis

1977 • 15 citations

Immunosuppression of experimental autoimmune myasthenia gravis by azathioprine. II. Evaluation of immunological mechanism.

1977 • 13 citations

Effect of azathioprine on the affinity of antibodies against acetylcholine receptor: Analysis with purified antibodies

1979 • 8 citations

Proceedings: Animal model for myasthenia gravis: acetylcholine receptor-induced myasthenia in rabbits, guinea pigs and monkeys.

1975 • 6 citations