Pharmacokinetics of cyclosporin A

Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A

1984 • 1,670 citations

Forecasting individual pharmacokinetics

1979 • 438 citations

A Radioimmunoassay to Measure Cyclosporin a in Plasma and Serum Samples

1981 • 287 citations

INDIVIDUALIZATION OF CYCLOSPORINE THERAPY USING PHARMACOKINETIC AND PHARMACODYNAMIC PARAMETERS

1985 • 278 citations

Role of lipoproteins and erythrocytes in the in vitro binding and distribution of cyclosporin A in the blood

1982 • 271 citations

Critical issues in cyclosporine monitoring: report of the Task Force on Cyclosporine Monitoring.

1987 • 233 citations

Cyclosporine Monitoring in Renal Transplantation

1989 • 130 citations

DEMOGRAPHIC FACTORS AFFECTING THE PHARMACOKINETICS OF CYCLOSPORINE ESTIMATED BY RADIOIMMUNOASSAY

1986 • 128 citations

Intraindividual variability in the relative systemic availability of cyclosporin after oral dosing

1988 • 124 citations

Age-dependent cyclosporine: Pharmacokinetics in marrow transplant recipients

1986 • 92 citations

Tissue distribution, disposition, and metabolism of cyclosporine in rats.

1987 • 90 citations

THE EFFECT OF FOOD ON CYCLOSPORINE ABSORPTION

1985 • 90 citations

Biotransformation and distribution in blood of cyclosporine and its metabolites.

1986 • 89 citations

Interaction of cyclosporin A with human lipoproteins

1986 • 85 citations

Intestinal lymphatic absorption of cyclosporin a following oral administration in an olive oil solution in rats

1983 • 82 citations

THE EFFECT OF ORAL METOCLOPRAMIDE ON THE ABSORPTION OF CYCLOSPORINE

1987 • 77 citations

Pharmacokinetics of oral cyclosporin a (Sandimmun) in healthy subjects

1986 • 76 citations

Pharmacokinetics and Monitoring of Cyclosporine Following Orthotopic Liver Transplantation

1985 • 75 citations

Biliary Excretion of Cyclosporine in Liver Transplant Patients.

1985 • 69 citations

Cyclosporin: measurement of fraction unbound in plasma

1987 • 68 citations

The transport of cyclosporine in association with plasma lipoproteins in heart and liver transplant patients.

1985 • 53 citations

Effect of hematocrit on cyclosporine (cyclosporin A) in whole blood and plasma of renal-transplant patients.

1985 • 47 citations

Absorption of cyclosporine A after oral dosing.

1986 • 44 citations

Inhibition of hepatic microsomal drug metabolism by the immunosuppressive agent cyclosporin A

1986 • 38 citations

PHARMACOKINETICS OF INTRAVENOUS CYCLOSPORINE IN BONE MARROW TRANSPLANT PATIENTS

1984 • 35 citations

Promotion of the selective lymphatic delivery of cyclosporin A by lipid-surfactant mixed micelles.

1985 • 35 citations

Distribution and transfer of cyclosporine among the various human lipoprotein classes

1983 • 34 citations

Saturable binding of cyclosporin A to erythrocytes: estimation of binding parameters in renal transplant patients and implications for bioavailability assessment.

1988 • 33 citations

EVIDENCE OF A CYCLOSPORINE-BINDING PROTEIN IN HUMAN ERYTHROCYTES

1986 • 27 citations

CYCLOSPORINE ABSORPTION IN INTESTINAL TRANSPLANTATION

1985 • 27 citations

Enhanced selective lymphatic delivery of cyclosporin a by solubilizers and intensified immunosuppressive activity against mice skin allograft.

1986 • 25 citations

A new method for measuring the free fraction of cyclosporin in plasma by equilibrium dialysis

1987 • 25 citations

The pharmacokinetics of cyclosporine. II. Blood plasma distribution and binding studies.

1985 • 24 citations

The chronopharmacokinetics of cyclosporine and its metabolites in recipients of pancreas allografts.

1988 • 21 citations

THE IMPACT OF STEADY-STATE CYCLOSPORINE CONCENTRATIONS ON RENAL ALLOGRAFT OUTCOME1,2

1990 • 20 citations

Significance of cyclosporine pharmacokinetics.

1988 • 19 citations

The free fraction of cyclosporine in plasma: clinical findings with a new method.

1988 • 17 citations

Cyclosporine levels are not helpful.

1988 • 16 citations

Influence of Demographic Factors on Cyclosporine Pharmacokinetics in Adult Uremic Patients

1989 • 15 citations

Influence of biliary T tube clamping on cyclosporine pharmacokinetics in liver transplant recipients.

1988 • 13 citations

Cyclosporine blood level monitoring: the early posttransplant period.

1986 • 12 citations

A safer approach to the clinical use of cyclosporine: the predose calculation.

1986 • 10 citations

An application of population pharmacokinetics to the clinical use of cyclosporine in bone marrow transplant patients.

1988 • 10 citations

VERY HIGH CONCENTRATION IN INTESTINAL LYMPH AFTER ORAL, BUT NOT AFTER INTRAVENOUS, CYCLOSPORINE IN THE RAT

1985 • 9 citations

Comparison and correlation of assays for monitoring cyclosporine drug levels in renal transplant recipients.

1988 • 7 citations

Pharmacokinetic evaluation of the blood‐to‐lymph transfer of cyclosporin a in rats

1983 • 7 citations

The effect of end-to-side portacaval shunt on cyclosporine pharmacokinetics in rats.

1989 • 1 citations