A de novo and heterozygous gene deletion causing a variant of von Willebrand disease

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies

1966 • 4,504 citations

Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man

1988 • 883 citations

A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16

1985 • 715 citations

Mutation rates differ among regions of the mammalian genome

1989 • 593 citations

The complex multimeric composition of factor VIII/von Willebrand factor

1981 • 572 citations

Amino acid sequence of human von Willebrand factor

1986 • 486 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

von Willebrand factor and von Willebrand disease [published erratum appears in Blood 1988 Mar;71(3):830]

1987 • 435 citations

Stabilization of Factor VIII in Plasma by the von Willebrand Factor

1977 • 421 citations

Human von Willebrand Factor (vWF): Isolation of Complementary DNA (cDNA) Clones and Chromosomal Localization

1985 • 420 citations

von Willebrand factor and von Willebrand disease [published erratum appears in Blood 1988 Mar;71(3):830]

1987 • 311 citations

Cloning and characterization of two cDNAs coding for human von Willebrand factor.

1985 • 302 citations

Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium

1974 • 265 citations

Von Willebrand factor in the vessel wall mediates platelet adherence

1985 • 204 citations

cDNA sequences for human von Willebrand factor reveal five types of repeated domains and five possible protein sequence polymorphisms

1986 • 204 citations

The propeptide of von Willebrand Factor independently mediates the assembly of von Willebrand multimers

1988 • 192 citations

Response to infusions of polyelectrolyte fractionated human factor VIII concentrate in human haemophilia A and von Willebrand's disease

1982 • 180 citations

Gene deletions correlate with the development of alloantibodies in von Willebrand disease.

1987 • 170 citations

Molecular cloning of cDNA for human von willebrand factor: Authentication by a new method

1985 • 162 citations

Construction of cDNA coding for human von Willebrand factor using antibody probes for colony-screening and mapping of the chromosomal gene

1985 • 157 citations

Homozygous and heterozygous deletions of the von Willebrand factor gene in patients and carriers of severe von Willebrand disease.

1988 • 102 citations

Von Willebrand's Disease

1983 • 99 citations

Von Willebrand Disease

1985 • 83 citations

The molecular basis of hemophilia A in man

1988 • 68 citations

Molecular cloning of the human gene for von Willebrand factor and identification of the transcription initiation site.

1987 • 50 citations

Human von Willebrand factor: The molecular glue of platelet plugs

1988 • 45 citations

The human von Willebrand factor gene

1988 • 41 citations

Sublocalization of von Willebrand factor pseudogene to 22q11.22?q11.23 by in situ hybridization in a 46,X,t(X;22)(pter;q11.21) translocation

1989 • 34 citations

Genetic linkage of two intragenic restriction fragment length polymorphisms with von Willebrand's disease type IIA. Evidence for a defect in the von Willebrand factor gene.

1988 • 30 citations

A polymorphism of the human von Willebrand factor (vWf) gene withBamHI

1986 • 29 citations

RFLP for a human von Willebrand factor (vWF) cDNA clone, pvWF1100

1985 • 29 citations

Von Willebrand disease investigated by two novel RFLPs

1988 • 28 citations

The Evaluation of Factor VIII Antigen by Means of a Simple Slide Test

1985 • 26 citations

Expression of abnormal von Willebrand factor by endothelial cells from a patient with type IIA von Willebrand disease.

1987 • 25 citations

Carrier Detection in Severe (Type III) von Willebrand Disease Using Two Intragenic Restriction Fragment Length Polymorphisms

1988 • 25 citations

The human gene for von willebrand factor. Identification of repetitive ALU sequences 5′ to the transcription initiation site

1988 • 24 citations

A polymorphic Xba I site within the human von Willebrand factor (vWF) gene identified by a vWF cDNA clone

1986 • 23 citations

The varieties of von Willebrand's disease

2008 • 22 citations

Factor XII gene alteration in Hageman trait detected by TaqI restriction enzyme

1987 • 21 citations

Partial factor IX protein in a pedigree with hemophilia B due to a partial gene deletion.

1986 • 20 citations

VON WILLEBRAND FACTOR, NOW CLONED

1986 • 19 citations

Two TaqI RFLPs in the human von Willebrand factor gene

1987 • 15 citations

Characterization of polymorphic markers in the von Willebrand factor gene and pseudogene

1990 • 12 citations

Multiple polymorphic sites in factor X locus

1988 • 12 citations

Two additional TaqI RFLPs in von Willebrand factor gene (VWF) and pseudogene

1989 • 6 citations