Homologous chromosome recombination generating immunoglobulin allotype and isotype switch variants.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Ribonucleic acid isolated by cesium chloride centrifugation

1974 • 2,263 citations

Selected methods in cellular immunology

1981 • 1,915 citations

Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

1980 • 803 citations

SOMATIC CROSSING OVER AND SEGREGATION IN DROSOPHILA MELANOGASTER

1936 • 540 citations

Polyadenylic Acid Sequences in the Heterogeneous Nuclear RNA and Rapidly-Labeled Polyribosomal RNA of HeLa Cells: Possible Evidence for a Precursor Relationship

1971 • 503 citations

Gene conversion: Some implications for immunoglobulin genes

1981 • 496 citations

Fluorescent phycobiliprotein conjugates for analyses of cells and molecules.

1982 • 455 citations

Organization of immunoglobulin heavy chain genes and allelic deletion model.

1978 • 297 citations

Genetic Analysis Based on Mitotic Recombination

1958 • 273 citations

Use of Monoclonal Anti-mouse Immunoglobulin to Detect Mouse Antibodies

1981 • 252 citations

Correlation between segmental flexibility and effector function of antibodies

1984 • 235 citations

Complete sequence of constant and 3′ noncoding regions of an immunoglobulin mRNA using the dideoxynucleotide method of RNA sequencing

1978 • 211 citations

Immunoglobulin class switching

1984 • 208 citations

Somatic Translocation of Antibody Genes

1970 • 178 citations

Mouse histocompatibility genes: structure and organisation of a Kd gene.

1983 • 176 citations

Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line

1982 • 173 citations

Rapid Methods and Automation in Microbiology and Immunology

1985 • 163 citations

Regulation of the antibody response

1969 • 155 citations

Localization of murine Ig-1b and Ig-1a (IgG 2a) allotypic determinants detected with monoclonal antibodies

1979 • 134 citations

[19] Fluorescence-activated cell sorting: Theory, experimental optimization, and applications in lymphoid cell biology

1984 • 127 citations

Gene conversion and polymorphism: Generation of mouse immunoglobulin γ2a chain alleles by differential gene conversion by γ2b chain gene

1983 • 119 citations

Rapid isolation of cloned isotype switch variants using fluorescence activated cell sorting

1982 • 112 citations

Immunoglobulin heavy-chain class switching in a pre-B cell line is accompanied by DNA rearrangement

1983 • 105 citations

Multiple DNA fragment polymorphisms associated with immunoglobulin mu chain switch-like regions in man.

1983 • 102 citations

Isolation of variants of mouse myeloma X63 that express changed immunoglobulin class.

1980 • 101 citations

Complete sequence of an immunoglobulin mRNA using specific priming and the dideoxynucleotide method of RNA sequencing

1981 • 90 citations

Immunoglobulin V region variants in hybridoma cells. II. Recombination between V genes.

1982 • 86 citations

Variants of a mouse myeloma cell line that synthesize immunoglobulin heavy chains having an altered serotype.

1975 • 84 citations

Switch from hapten-specific immunoglobulin M to immunoglobulin D secretion in a hybrid mouse cell line.

1981 • 78 citations

Genetic demonstration of mitotic recombination in cultured chinese hamster cell hybrids

1984 • 69 citations

Isolation of myeloma variants with predefined variant surface immunoglobulin by cell sorting.

1978 • 65 citations

Spontaneous Immunoglobulin Class Switching in Myeloma and Hybridoma Cell Lines Differs from Physiological Class Switching

1982 • 53 citations

Molecular basis of an isogeneic anti-idiotypic response.

1984 • 51 citations

Alteration by Mitomycin C of Spot Frequencies in Soybean Leaves

1968 • 50 citations

Genetic characterization of mouse immunoglobulin allotypic determinants (allotopes) defined by monoclonal antibodies.

1983 • 42 citations

Mouse immunoglobulin allotypes: post-duplication divergence of γ2a and γ2b chain genes

1982 • 37 citations

Isolation of heavy chain class switch variants of a monoclonal anti-DC1 hybridoma cell line: Effective conversion of noncytotoxic IgG1 antibodies to cytotoxic IgG2 antibodies

1983 • 34 citations

Evidence for Mitotic Recombination in the Cellular Slime Mold Dictyostelium discoideum

1974 • 31 citations

Evidence for gene conversion among immunoglobulin heavy chain variable region genes.

1984 • 31 citations

Allelic inclusion in the pre-B-cell line 18-81.

1984 • 23 citations

Critical test of a sister chromatid exchange model for the immunoglobulin heavy-chain class switch

1985 • 22 citations

New immunoglobulin IgG allotypes and haplotypes found in wild mice with monoclonal anti-allotope antibodies.

1982 • 19 citations

Hybrid gamma 2b-gamma 2a genes expressed in myeloma variants: evidence for homologous recombination.

1983 • 11 citations

Immunoglobulin isoantigens (allotypes) in the mouse. IV. Allotypic specificities common to two distinct immunoglobulin classes.

1967 • 10 citations

Localization of murine Igh-1a allotypic determinants by using a panel of mouse myeloma variant immunoglobulins.

1983 • 8 citations