Stereotyped Behavior and Its Relevance for Testing Neuroleptics

Handbook of Psychopharmacology

1988 • 2,778 citations

Antipsychotic drug doses and neuroleptic/dopamine receptors

1976 • 1,623 citations

Advances in biochemical psychopharmacology

1970 • 1,186 citations

Handbook of Psychopharmacology

1978 • 1,034 citations

Cocaine and Other Stimulants

1988 • 982 citations

Advances in Biochemical Psychopharmacology

1970 • 760 citations

Stereotyped activities produced by amphetamine in several animal species and man

1967 • 612 citations

Amphetamine Psychosis: A "Model" Schizophrenia Mediated by Catecholamines

1973 • 590 citations

Neuropathology of Schizophrenia

1982 • 472 citations

Comparative studies of various amphetamine analogues demonstrating different interactions with the metabolism of the catecholamines in the brain

1971 • 405 citations

The Experimental Reproduction of Amphetamine Psychosis

1973 • 350 citations

IS IT POSSIBLE TO PREDICT THE CLINICAL EFFECTS OF NEUROLEPTIC DRUGS (MAJOR TRANQUILLIZERS) FROM ANIMAL DATA?I. "NEUROLEPTIC ACTIVITY SPECTRA" FOR RATS.

1965 • 348 citations

Comparison of Amphetamine Psychosis and Schizophrenia

1965 • 328 citations

Amphetamine psychosis: Behavioral and biochemical aspects

1974 • 325 citations

Neuroleptic drug interactions with norepinephrine alpha receptor binding sites in rat brain

1977 • 290 citations

Behavioural stimulation induced by muscimol and other GABA agonists injected into the substantia nigra

1977 • 279 citations

ADVANCES IN BEHAVIORAL BIOLOGY

1972 • 271 citations

Uptake inhibition of biogenic amines by newer antidepressant drugs: Relevance to the dopamine hypothesis of depression

1977 • 264 citations

Catecholamines and Behavior · 1

1975 • 262 citations

Evolving Behavior in the Clinical and Experimental Amphetamine (Model) Psychosis

1973 • 253 citations

International Symposium on Pain

1974 • 243 citations

Current Developments in Psychopharmacology

1978 • 242 citations

Pharmacology and physiology of stereotyped behavior

1974 • 238 citations

Phenothiazine Effects on Psychological and Psychophysiological Dysfunction in Chronic Schizophrenics

1977 • 235 citations

Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine

1975 • 206 citations

Methylphenidate, Dextroamphetamine, and Levamfetamine

1976 • 205 citations

Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: Evidence for two different mechanisms of action

1978 • 198 citations

Adrenergic Mechanisms and Amphetamine Induced Abnormal Behaviour

1963 • 198 citations

Schizophrenia : current concepts and research

1969 • 175 citations

Metoclopramide and dopamine receptor blockade

1976 • 157 citations

Special antagonism of amphetamine-induced abnormal behaviour

1965 • 156 citations

Amphetamine Induced Selective Stimulation of Certain Behaviour Items With Concurrent Inhibition of Others in an Open-Field Test With Rats

1971 • 154 citations

Psychoses and the punding and choreiform syndromes in addiction to central stimulant drugs.

1972 • 151 citations

The Antagonism of Amphetamine-Induced Symptomatology by a Neuroleptic

1974 • 149 citations

Detection of the neuroleptic properties of clozapine, sulpiride and thioridazine

1975 • 146 citations

Biochemical differentiation of amphetamine vs methylphenidate and nomifensine in rats

1977 • 145 citations

Behavioural Stereotypies Induced by Pharmacological Agents

1968 • 142 citations

gamma-Aminobutyric acid (Gaba) and the dopamine hypothesis of schizophrenia

1977 • 141 citations

Diethyldithiocarbamate and amphetamine stereotype behaviour

1966 • 133 citations

Substituted benzamides as cerebral dopamine antagonists in rodents

1977 • 129 citations

Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data?

1966 • 125 citations

Differential attenuation of some effects of haloperidol in rats given scopolamine

1976 • 117 citations

Haloperidol-induced tardive dyskinesia in monkeys

1976 • 117 citations

On the significance of regional dopamine metabolism in the rat brain for the classification of centrally acting drugs

1977 • 117 citations

Aminergic Systems in Basal Ganglia Associated with Stereotyped Hyperactive Behavior and Catalepsy

1968 • 116 citations

A comparison of the abilities of typical neuroleptic agents and of thioridazine, clozapine, sulpiride and metoclopramide to antagonise the hyperactivity induced by dopamine applied intracerebrally to areas of the extrapyramidal and mesolimbic system

1976 • 115 citations

Behavioral evidence for supersensitivity after chronic administration of haloperidol, clozapine, and thioridazine

1976 • 111 citations

Effects of clozapine, thioridazine, perlapine and haloperidol on the metabolism of the biogenic amines in the brain of the rat

1975 • 107 citations

The influence of various neuroleptic drugs on shock avoidance responding in rats

1970 • 102 citations

Chronic phenylethylamine stereotypy in rats: A new animal model for schizophrenia?

1977 • 94 citations

DOPA AND OTHER NATURALLY OCCURRING SUBSTANCES AS CAUSES OF STEREOTYPY AND RAGE IN RATS

1966 • 92 citations

Psychoses Due to Amphetamine Consumption

1960 • 91 citations

The effects of antipsychotics on the turnover rate of GABA and acetylcholine in rat brain nuclei

1976 • 87 citations

The dose-response effect of amphetamine upon avoidance behaviour in the rat seen as a function of increasing stereotypy

1972 • 86 citations

ON THE RELEVANCE OF PREFERENTIAL INCREASES OF MESOLIMBIC VERSUS STRIATAL DOPAMINE TURNOVER FOR THE PREDICTION OF ANTIPSYCHOTIC ACTIVITY OF PSYCHOTROPIC DRUGS

1976 • 85 citations

Biological mechanisms of schizophrenia and schizophrenia-like psychoses

1975 • 85 citations

Differential sensitivity of two dopaminergic structures in rat brain to haloperidol and to clozapine.

1975 • 80 citations

An open field study of stereotyped locomotor activity in amphetamine-treated rats

1979 • 77 citations

Amphetamine as a model for hyperactivity in the rat☆

1973 • 77 citations

The Significance of Dopamine for the Mode of Action of Neuroleptics and the Pathogenesis of Schizophrenia

1977 • 75 citations

Noncatecholic Phenylethylamines

1980 • 74 citations

Regional effects of neuroleptics of dopamine metabolism and dopamine-sensitive adenylate cyclase activity

1977 • 74 citations

PSYCHOTROPIC DRUGS AND DYSFUNCTIONS OF THE BASAL GANGLIA

1971 • 71 citations

Antagonism of Methylphenidate‐Induced Stereotyped Gnawing in Mice

1972 • 67 citations

Pharmacokinetic and clinical studies on amphetamine dependent subjects

1970 • 64 citations

Changes in Individual and Social Behavior Induced by Amphetamine and Related Compounds in Monkeys and Man

1977 • 64 citations

A schizophreniform behavioral psychosis mediated by dopamine

1975 • 63 citations

Cardiovascular dopamine receptor stimulation antagonized by metoclopramide

1975 • 62 citations

Anticholinergic properties of antipsychotic drugs and their relation to extrapyramidal side-effects

1976 • 59 citations

Further studies on the antagonism of stereotyped behaviour induced by amphetamine

1969 • 58 citations

The Classification of the Functional Psychoses

1973 • 54 citations

Central Nervous System Stimulants: Historical Aspects and Clinical Effects

1978 • 53 citations

AMPHETAMINE WITHDRAWAL: DEPRESSION AND M.H.P.G. EXCRETION

1971 • 52 citations

The induction and antagonism of central nervous system stimulant-induced stereotyped behavior in the cat

1972 • 47 citations

Effects of chronic d-amphetamine on social behavior of the rat: Implications for an animal model of paranoid schizophrenia

1976 • 47 citations

Clozapine: Reduction of the initial dopamine turnover increase by repeated treatment

1976 • 45 citations

Stages of constant amphetamine intoxication: Delayed appearance of abnormal social behaviors in rat colonies

1978 • 45 citations

The effects of methylamphetamine on stereotyped behaviour, activity, startle, and orienting responses

1972 • 36 citations

Amphetamine-induced catecholamine activation in schizophrenia and depression: behavioral and physiological effects.

1977 • 36 citations

A two factor theory of schizophrenia

1974 • 35 citations

Behavioral patterns related to dopamine neurotransmission: effect of acute and chronic antipsychotic drugs.

1977 • 35 citations

Brain dopamine and the amphetamine-reserpine interaction

1967 • 34 citations

Inhibition and potentiation of apomorphine-induced hypermotility in rats by neuroleptics

1976 • 33 citations

Psychopharmacological Agents

1967 • 32 citations

Social Isolation and Changes in the Formation of Groups induced by Amphetamine in an Open-Field Test with Rats^*

1971 • 31 citations

The Clinical Symptomatology of Amphetamine Psychosis and its Relationship to Amphetamine Levels in Urine

1969 • 30 citations

Apomorphine-Induced Stereotyped Biting in the Tortoise in Relation to Dopaminergic Mechanisms

1975 • 30 citations

Behavioural Disorders in Japanese Monkeys Produced by the Long-term Administration of Methamphetamine

1970 • 29 citations

Catecholamines in Activation, Stereotypy, and Level of Mood

1975 • 26 citations

Amphetamine Substances in Mental Illnesses in Northern Ireland

1963 • 25 citations

A Case of Recurrent Psychosis Associated with Amphetamine Addiction

1950 • 25 citations

Chronic amphetamine treatment: vast individual differences in performing a learned response

1974 • 23 citations

Stereotypy with Selective Stimulation of Certain Items of Behaviour Observed in Amphetamine-treated Monkeys (Cercopithecus)

1972 • 22 citations

A new comparative physiognomy of neuroleptics: a collaborative clinical report.

1972 • 20 citations

Effects of molindone on central dopaminergic neuronal activity and metabolism: similarity to other neuroleptics.

1975 • 20 citations

Disruption of Social Behaviour of Vervet Monkeys (Cercopithecus) by Low Doses of Amphetamines

1973 • 20 citations

Behavioral effects of low, acute doses of d-amphetamine on the dyadic interaction between mother and infant vervet monkeys (Cercopithecus aethiops) during the first six postnatal months

1979 • 19 citations

Neuroleptic Action of Clozapine Injected into Various Brain Areas in Rats

1975 • 17 citations

Psychopharmacological effects of thiothixene and related compounds

1968 • 17 citations

Psychopharmacology of amphetamines.

1972 • 17 citations

Effects of clozapine and other dibenzo-epines on central dopaminergic and cholinergic systems. Structure-activity relationships.

1977 • 17 citations

The effect of antipsychotic drugs and their clinically inactive analogs on dopamine metabolism

1977 • 17 citations

Normalization by antipsychotic drugs of biochemically induced abnormal behavior in rats

1976 • 15 citations

Symposium on Pharmacological Agents and Biogenic Amines in the Central Nervous System

1973 • 15 citations

Pharmacological evidence for a cholinergic mechanism in brain involved in a special stereotyped behaviour of reserpinized rats.

1968 • 15 citations

Definition, Classification and Nomenclature: A Clinical Overview

1976 • 13 citations

Drug-induced Psychoses and their Relationship to Schizophrenia

1976 • 11 citations

Effects of a Single Administration of Clozapine on Mouse Brain Catecholamines

1976 • 10 citations

Evidence for a cholinergic mechanism in brain involved in the tetrabenazine reversal by thymoleptic drugs

1969 • 9 citations

Inhibition of Apomorphine‐induced Hypermotility in Rats by Chlorpromazinc, Perphenazine, Thioridazine and Melperone

1977 • 8 citations

Mass fragmentographic demonstration of low amounts of (3-phenylethylamine in human urine

1977 • 7 citations

Mass fragmentographic demonstration of low amounts of (3-phenylethylamine in human urine

1977 • 7 citations

Inhibition of Apomorphine-induced Hypermotility in Rats by Chlorpromazinc, Perphenazine, Thioridazine and Melperone

1977 • 7 citations

INTRACEREBRAL LESIONS CAUSING STEREOTYPED BEHAVIOUR IN RATS

1971 • 6 citations

[Chronic alerting amine addiction in Japan].

1956 • 6 citations

Dissociable properties of dopamine neurons im the nigrostriatal and mesolimbic dopamine systems.

1977 • 5 citations

Partial restoration by a neuroleptic (spiramide) of items of grooming behaviour suppressed by amphetamine.

1974 • 4 citations

Interaction of neuroleptic and cholinergic drugs with central dopaminergic mechanisms

1974 • 4 citations

Altered receptor sensitivity following chronic drug administration in man: the tardive dyskinesia model [proceedings].

1977 • 4 citations

Analysis of the aggressiveness-stereotypy complex induced in mice by amphetamine or D,L-dopa. II.

1974 • 4 citations

Natural Reinforcement in a Psychiatric Rehabilitation Program*

1977 • 3 citations

Soteria House: one-year outcome data [proceedings].

1977 • 3 citations

Psychologic Test Responses and Methylphenidate

1977 • 3 citations

Action of classic and unusual neuroleptics on various behavioral apomorphine-induced effects.

1977 • 2 citations

Collegium Internationale Neuro-Psychopharmacologicum (C.I.N.P.)

1983 • 2 citations

The course of treatment in schizophrenia in relation to the presence of affective disturbances.

1975 • 2 citations

Interactions of substituted benzamide drugs with cerebral dopamine pathways [proceedings].

1977 • 1 citations