Thioridazine-fluoxetine interaction at the level of the distribution process in vivo.

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

The effect of selective serotonin re‐uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes.

1992 • 456 citations

Fluvoxamine is a potent inhibitor of cytochrome P4501A2

1993 • 370 citations

Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine

1996 • 314 citations

The potential role of lysosomes in tissue distribution of weak bases

1988 • 200 citations

Selective Serotonin Reuptake Inhibitors and CNS Drug Interactions

1997 • 167 citations

The binding of drugs to different polar lipids in vitro

1979 • 121 citations

Contribution of Lysosomal Trapping to the Total Tissue Uptake of Psychotropic Drugs

1997 • 106 citations

Binding of basic and acidic drugs to rat tissue subcellular fractions

1974 • 80 citations

Fluvoxamine and fluoxetine: interaction studies with amitriptyline, clomipramine and neuroleptics in phenotyped patients

1995 • 75 citations

Drug distribution between blood and brain as a determinant of antipsychotic drug effects

1992 • 73 citations

Role of Lysosomes in Hepatic Accumulation of Chloroquine

1988 • 70 citations

The Contribution of Lysosomal Trapping in the Uptake of Desipramine and Chloroquine by Different Tissues

1995 • 60 citations

The Role of Lysosomes in the Cellular Distribution of Thioridazine and Potential Drug Interactions

1999 • 59 citations

Intracellular distribution of psychotropic drugs in the grey and white matter of the brain: the role of lysosomal trapping

2001 • 59 citations

Membrane lipids as intracellular binders of chlorpromazine and related drugs

1977 • 56 citations

Interactions of chlorpromazine and imipramine with artificial membranes investigated by equilibrium dialysis, dual-wavelength photometry, and fluorimetry

1979 • 55 citations

Lysosomal trapping as an important mechanism involved in the cellular distribution of perazine and in pharmacokinetic interaction with antidepressants

1999 • 54 citations

Plasma Concentrations of Thioridazine Metabolites and ECG Abnormalities

1978 • 37 citations

Distribution interactions between perazine and antidepressant drugs. In vivo studies.

2001 • 26 citations

Interactions between Promazine and Antidepressants at the Level of Cellular Distribution

1997 • 24 citations

Cardiac Function in Patients Treated with Phenothiazines. Comparison with Quinidine

1974 • 22 citations

The influence of selective serotonin reuptake inhibitors on the plasma and brain pharmacokinetics of the simplest phenothiazine neuroleptic promazine in the rat

1999 • 18 citations

The influence of selective serotonin reuptake inhibitors (SSRIs) on the pharmacokinetics of thioridazine and its metabolites: in vivo and in vitro studies

1999 • 17 citations

Pharmacokinetics of thioridazine and its metabolites in blood plasma and the brain of rats after acute and chronic treatment.

1998 • 17 citations

The effect of selective serotonin reuptake inhibitors (SSRIs) on the pharmacokinetics and metabolism of perazine in the rat

2001 • 12 citations