High Fidelity Devices in the Reproduction of DNA

The Selfish Gene

1976 • 10,856 citations

Selfish DNA: the ultimate parasite

1980 • 2,095 citations

Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli

1976 • 1,572 citations

Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

1974 • 1,532 citations

Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.

1976 • 942 citations

Complementary base pairing and the origin of substitution mutations

1976 • 835 citations

Kinetic amplification of enzyme discrimination

1975 • 742 citations

The Oxford University Press, 1468–192

1922 • 705 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1972 • 594 citations

EUKARYOTIC CHROMOSOME REPLICATION

1975 • 455 citations

Molecular and environmental aspects of mutagenesis

1976 • 444 citations

Extreme sensitivity of some intestinal crypt cells to X and γ irradiation

1977 • 417 citations

Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction.

1980 • 391 citations

Complementary specificity of restriction endonucleases of Diplococcus pneumoniae with respect to DNA methylation

1977 • 369 citations

BACTERIAL MUTATOR GENES AND THE CONTROL OF SPONTANEOUS MUTATION

1976 • 342 citations

Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn I endonuclease.

1979 • 339 citations

Repair tracts in mismatched DNA heteroduplexes.

1976 • 300 citations

Genetic Recombination: Strand Transfer and Mismatch Repair

1978 • 270 citations

Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA.

1977 • 265 citations

Prebiotic chemistry and nucleic acid replication

1974 • 233 citations

A Factor (or Mutator Gene) Influencing Mutation Rates in Escherichia Coli

1954 • 229 citations

Location of DNA methylation genes on the Escherichia coli K-12 genetic map

1973 • 211 citations

Mutational specificity of a conditional Escherichia coli mutator, mutD5

1974 • 200 citations

Recent excitement in the DNA replication problem

1977 • 193 citations

Studies on the biochemical basis of spontaneous mutation

1974 • 170 citations

Error induction and correction by mutant and wild type T4 DNA polymerases. Kinetic error discrimination mechanisms.

1979 • 167 citations

Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: spontaneous mutation by misincorporation.

1979 • 165 citations

Progress in Environmental Mutagenesis

1981 • 163 citations

Escherichia coli mutants uvr D and uvr E deficient in gene conversion of λ-heteroduplexes

1975 • 154 citations

On the Fidelity of DNA Replication

1979 • 144 citations

Molecular mechanisms of induced mutagenesis

1977 • 143 citations

SELECTION FOR HIGH MUTATION RATES IN CHEMOSTATS

1974 • 142 citations

A Comparison of Associated Enzyme Activities in Various Deoxyribonucleic Acid Polymerases

1973 • 126 citations

Bromouracil mutagenesis and mismatch repair in mutator strains of Escherichia coli

1978 • 121 citations

SELECTIVE ALLELE LOSS IN MIXED INFECTIONS WITH T4 BACTERIOPHAGE

1973 • 121 citations

IS THERE SOS INDUCTION IN MAMMALIAN CELLS?

1980 • 121 citations

Escherichia coli K-12 mutants deficient in uracil-DNA glycosylase

1978 • 120 citations

Low Molecular Weight Deoxyribonucleic Acid Polymerase from Calf Thymus Chromatin

1973 • 110 citations

A high molecular weight DNA polymerase from Drosophila melanogaster embryos. Purification, structure, and partial characterization.

1979 • 108 citations

Phylogeny of DNA Polymerase-β

1976 • 107 citations

Hydrolysis of Template and Newly Synthesized Deoxyribonucleic Acid by the 3′ to 5′ Exonuclease Activity of the T4 Deoxyribonucleic Acid Polymerase

1972 • 105 citations

Characterization of DNA adenine methylation mutants of Escherichia coli K12

1979 • 103 citations

Escherichia coli mutants deficient in deoxyuridine triphosphatase

1978 • 103 citations

Fidelity of DNA replication catalysed in vitro on a natural DNA template by the T4 bacteriophage multi-enzyme complex

1980 • 103 citations

Replicational Fidelity: Mechanisms of Mutation Avoidance and Mutation Fixation

1979 • 96 citations

Structural and Energetic Consequences of Noncomplementary Base Oppositions in Nucleic Acid Helices

1975 • 89 citations

On the Role of Deoxyribonucleic Acid Polymerase in Determining Mutation Rates

1973 • 85 citations

Control of mutation frequency by bacteriophage T4 DNA polymerase. I. The CB120 antimutator DNA polymerase is defective in strand displacement.

1976 • 84 citations

A high molecular weight DNA polymerase from Drosophila melanogaster embryos. Purification, structure, and partial characterization.

1979 • 82 citations

Single-strand binding protein enhances fidelity of DNA synthesis in vitro.

1979 • 80 citations

Mechanism of selective inhibition of 3' to 5' exonuclease activity of Escherichia coli DNA polymerase I by nucleoside 5'-monophosphates

1978 • 68 citations

Stimulation of mutation in phage T4 by lesions in gene 32 and by thymidine imbalance

1972 • 62 citations

Isolation of an Escherichia coli K-12 dnaE mutation as a mutator

1978 • 42 citations

The accuracy of DNA replication

1979 • 41 citations

Mutator action by Escherichia coli strains carrying dnaE mutations

1977 • 39 citations

A new approach to DNA polymerase kinetics

1979 • 33 citations

Increased spontaneous reversion of certain frameshift mutations in DNA polymerase I deficient strains of Escherichia coli

1975 • 30 citations

Genetic analysis of host range mutant viruses suggests an uncoating defect in simian virus 40-resistant monkey cells

1977 • 26 citations

Mutator mutations in bacteriophage T4 gene 32 (DNA unwinding protein)

1976 • 17 citations

Evolution of fitness, 3. Improvement of fitness in irradiated populations of Drosophila serrata.

1967 • 13 citations