ACETYLATION OF DRUGS

Tissue sulfhydryl groups

1959 • 25,130 citations

Catalysis in chemistry and enzymology

1969 • 3,236 citations

A NEW COUPLING COMPONENT FOR SULFANILAMIDE DETERMINATION

1939 • 2,939 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products☆I. Nomenclature and rate equations

1963 • 2,095 citations

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

1963 • 1,885 citations

Determination of sulfhydryl groups with 2,2′- or 4,4′-dithiodipyridine

1967 • 978 citations

Genetic Control of Isoniazid Metabolism in Man

1960 • 792 citations

DETOXICATION MECHANISMS

1960 • 760 citations

Enzyme Kinetics

1967 • 368 citations

HUMAN ACETYLATION POLYMORPHISM.

1964 • 301 citations

ACETYLATION OF SULFANILAMIDE BY LIVER HOMOGENATES AND EXTRACTS

1945 • 284 citations

Biosynthesis of melatonin: enzymic conversion of serotonin to N-acetylserotonin

1960 • 256 citations

An improved and simplified method of detecting the acetylator phenotype.

1969 • 238 citations

THE ENZYMATIC ACETYLATION OF AMINES

1953 • 209 citations

The polymorphic acetylation of dapsone in man

1971 • 163 citations

IS p-AMINOBENZENESULPHONAMIDE THE ACTIVE AGENT IN PRONTOSIL THERAPY ?

1937 • 156 citations

Health services in France.

1949 • 154 citations

Peripheral neuritis due to isoniazid.

1960 • 149 citations

The Genetics of Migrant and Isolate Populations.

1964 • 145 citations

Genetical and Geographic Studies on Isoniazid Inactivation

1961 • 132 citations

Partial purification and properties of the isoniazid transacetylase in human liver. Its relationship to the acetylation of p-aminosalicylic acid.

1965 • 132 citations

On the metabolic fate of isoniazid.

1953 • 104 citations

Handbuch der experimentellen Pharmakologie

1972 • 104 citations

The influence of acetylator phenotype on the effects of treating depression with phenelzine

1965 • 95 citations

Studies on the metabolic basis for the genetically determined capacities for isoniazid inactivation in man.

1965 • 81 citations

�ber die Erbbedingtheit der intraindividuellen Konstanz der Isoniazidausscheidung beim Menschen (Untersuchungen an eineiigen und zweieiigen Zwillingen)

1957 • 78 citations

Diphenylhydantoin intoxication attendant to slow inactivation of isoniazid

1970 • 75 citations

Sulphadimidine Acetylation Test for Classification of Patients as Slow or Rapid Inactivators of Isoniazid

1970 • 73 citations

N-acetylation of drugs: isolation and properties of an N-acetyltransferase from rabbit liver.

1967 • 72 citations

Acetylation of Para-Aminobenzenesulfonamide in the Animal Organism

1937 • 67 citations

THE ACETYLATION OF SULFANILAMIDE IN VITRO

1938 • 62 citations

Acetylation and deacetylation of the p-amino group of sulphonamide drugs in animal tissues

1947 • 61 citations

INVESTIGATION OF THE GENETIC CONTROL OF SULFADIAZINE AND ISONIAZID METABOLISM IN THE RABBIT.

1963 • 60 citations

Genetics of Isoniazid Metabolism in Caucasian, Negro, and Japanese Populations

1964 • 59 citations

Metabolism of diphenylhydantoin by rat liver microsomes—i

1970 • 54 citations

The acetylation of sulfamethazine and sulfamethoxypyridazine by human subjects

1968 • 53 citations

GENETIC AND ENVIRONMENTAL FACTORS AFFECTING HEXOBARBITAL METABOLISM IN MICE

1968 • 52 citations

Conjugation Reactions in the Newborn Infant: The Metabolism of Para-aminobenzoic Acid

1965 • 52 citations

Acetyl coenzyme A and the fatty acid cycle.

1952 • 46 citations

PURIFICATION AND PROPERTIES OF N‐ACETYLTRANSFERASE FROM MAMMALIAN LIVER

1968 • 46 citations

Studies of Human Patterns of Isoniazid Metabolism Using an Intravenous Fall-off Technique with a Chemical Method¹

1960 • 45 citations

The enzymatic transacetylation between aromatic amines

1953 • 44 citations

Kinetic characteristics of the acetylation of isoniazid and p-aminosalicylic acid by a liver-enzyme preparation

1962 • 43 citations

Acetyl transfer in arylamine metabolism

1966 • 41 citations

The mechanism of isoniazid acetylation by human N-acetyltransferase

1968 • 36 citations

The frequency of isoniazid acetylase enzyme deficiency among Egyptians

1969 • 34 citations

The fluorometric measurement of 4,4'-diaminodiphenyl sulfone and its acetylated derivatives in plasma and urine.

1970 • 33 citations

The metabolism of sulphonamides

1948 • 33 citations

SULFONAMIDE ADMINISTRATION IN NEWBORN AND PREMATURE INFANTS

1956 • 31 citations

STUDIES OF GENETICALLY CONTROLLED SULFADIAZINE ACETYLATION IN RABBIT LIVERS: POSSIBLE IDENTIFICATION OF THE HETEROZYGOUS TRAIT.

1963 • 30 citations

Acetylation by blood cells

1955 • 27 citations

The relationship between the capacities of human subjects to acetylate isoniazid, sulfanilamide and sulfamethazine

1965 • 27 citations

Isotope exchange studies on rabbit liver N-acetyltransferase

1971 • 27 citations

The discrimination of phenotypes for rate of disappearance of isonicotinoyl hydrazide from serum

1969 • 25 citations

Drug metabolizing systems in homogenates of human immature placentas

1968 • 24 citations

A familial study of procainamide-induced systemic lupus erythematosus

1968 • 22 citations

Determination of Para-Aminosalicylic Acid in Blood.

1948 • 21 citations

Acylgruppenübertragung auf aromatische Amine durch Carboxylesterasen

1968 • 18 citations

Acetylation of 5-hydroxytryptamine by isoniazid N-acetyltransferase

1969 • 18 citations

N-Acetyl-transferase and Serotonin Metabolism in Man and, other Species, I

1969 • 17 citations

Acetylation of serotonin in vitro by a human N-acetyltransferase

1969 • 12 citations

Individual different response to drugs: Characterisation of an INH-acetylating system in rhesus monkeys

1967 • 12 citations

Studies on isoniazid conversion in Thailand

1967 • 9 citations

Generic Position of the South American Snake Tropidodipsas perijanensis

1970 • 7 citations

Acetylation of 6-sulphanilamidopyrimidines in the rabbit

1969 • 4 citations

Diphenylhydantoin-induced difference spectra with rat-liver microsomes

1970 • 4 citations

Deleted Work

1955 • 0 citations