Inhibition of Phospholipase A2 by Uteroglobin and Antiflammin Peptides

Rapid similarity searches of nucleic acid and protein data banks.

1983 • 1,577 citations

Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation

1979 • 928 citations

Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity

1986 • 671 citations

Inhibition of phospholipase A2 by "lipocortins" and calpactins. An effect of binding to substrate phospholipids.

1987 • 534 citations

Aggregation of chromaffin granules by calpactin at micromolar levels of calcium

1988 • 443 citations

"Blastokinin": Inducer and Regulator of Blastocyst Development in the Rabbit Uterus

1967 • 388 citations

Diversity in the lipocortin/calpactin family

1988 • 376 citations

Five distinct calcium and phospholipid binding proteins share homology with lipocortin I.

1988 • 364 citations

PROGESTERONE AND MAINTENANCE OF PREGNANCY: IS PROGESTERONE NATURE'S IMMUNOSUPPRESSANT?^*

1977 • 350 citations

Kinetic analysis of phospholipase A2 activity toward mixed micelles and its implications for the study of lipolytic enzymes

1975 • 278 citations

Asthma; physiology, immunopharmacology and treatment

1986 • 273 citations

Characterization of lipocortin I and an immunologically unrelated 33-kDa protein as epidermal growth factor receptor/kinase substrates and phospholipase A2 inhibitors.

1987 • 265 citations

Novel anti-inflammatory peptides from the region of highest similarity between uteroglobin and lipocortin I

1988 • 244 citations

Anti-phospholipase proteins

1984 • 228 citations

Tihe Concentrations of Progesterone, Estrone and Estradiol-17β in the Plasma of Pregnant Rabbits

1973 • 213 citations

Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.

1989 • 204 citations

Uteroglobin inhibits phospholipase A2 activity

1986 • 200 citations

Progesterone and progestins

1983 • 196 citations

Identification of chromaffin granule-binding proteins. Relationship of the chromobindins to calelectrin, synhibin, and the tyrosine kinase substrates p35 and p36.

1987 • 175 citations

Recombinant human lipocortin 1 inhibits thromboxane release from guinea-pig isolated perfused lung

1987 • 166 citations

Uteroglobin: Structure, Molecular Biology, and New Perspectives on Its Function as a Phospholipase A₂Inhibitor

1987 • 164 citations

Common domain structure of Ca²⁺ and lipid‐binding proteins

1986 • 138 citations

Refinement of the C2221 crystal form of oxidized uteroglobin at 1.34 Å resolution

1987 • 123 citations

Suppression of Epididymal Sperm Antigenicity in the Rabbit by Uteroglobin and Transglutaminase in Vitro

1983 • 123 citations

Human 67-kDa calelectrin contains a duplication of four repeats found in 35-kDa lipocortins.

1988 • 109 citations

Role of Uteroglobin and Transglutaminase in Masking the Antigenicity of Implanting Rabbit Embryos*

1982 • 105 citations

Progesterone Regulation of Blastokinin Production and Maintenance of Rabbit Blastocysts Transferred Into Uteri of Castrate Recipients

1972 • 99 citations

Cell Biology: Consensus in exocytosis

1986 • 99 citations

Advances in Inflammation Research

1985 • 89 citations

Inhibition of phagocyte chemotaxis by uteroglobin, an inhibitor of blastocyst rejection

1988 • 88 citations

Possible Involvement of Cytoskeleton in Collagen-stimulated Activation of Phospholipases in Human Platelets

1989 • 87 citations

Hydrolysis of phosphatidylcholine in phosphatidylcholine-cholate mixtures by porcine pancreatic phospholipase A2.

1988 • 85 citations

Antiinflammatory peptides (antiflammins) inhibit synthesis of platelet-activating factor, neutrophil aggregation and chemotaxis, and intradermal inflammatory reactions.

1990 • 85 citations

X-ray crystallographic analysis of a progesterone-binding protein. The C2221 crystal form of oxidized uteroglobin at 2.2 Å resolution

1980 • 85 citations

The chemical basis for interfacial activation of monomeric phospholipases A2. Autocatalytic derivatization of the enzyme by acyl transfer from substrate.

1988 • 84 citations

The activation of porcine pancreatic phospholipase A2 by dipalmitoylphosphatidylcholine large unilamellar vesicles. Analysis of the state of aggregation of the activated enzyme.

1987 • 83 citations

Purification and quaternary structure of the hormonally induced protein uteroglobin

1977 • 83 citations

Sedimentation equilibrium analysis of five lipocortin-related phospholipase A2 inhibitors from human placenta. Evidence against a mechanistically relevant association between enzyme and inhibitor.

1988 • 82 citations

Transglutaminase-Mediated Modifications of the Rat Sperm Surface in Vitro

1984 • 79 citations

The Temporal Sequence of Events in the Activation of Phospholipase A2 by Lipid Vesicles

1989 • 68 citations

[Progesterone and progestins].

1979 • 67 citations

Binding and inhibition studies on lipocortins using phosphatidylcholine vesicles and phospholipase A2 from snake venom, pancreas, and a macrophage-like cell line.

1990 • 61 citations

Servomechanism of Prolactin and Progesterone in Regulating Uterine

1988 • 59 citations

Who carries what message?

1989 • 59 citations

Computer Analysis of Enzyme-Substrate-Inhibitor Kinetic Data with Automatic Model Selection Using IBM-PC Compatible Microcomputers

1986 • 59 citations

Amino acid sequence of progesterone-induced rabbit uteroglobin

1978 • 58 citations

Immunological Evidence of Uteroglobin (Blastokinin) in the Male Reproductive Tract and in Nonreproductive Ductal Tissues and Their Secretions

1976 • 58 citations

Dimerization and activation of porcine pancreatic phospholipase A2 via substrate level acylation of lysine 56

1989 • 55 citations

Crosslinking of uteroglobin by transglutaminase

1984 • 52 citations

Development of a Radioimmunoassay for Blastokinin¹

1974 • 50 citations

Uteroglobin in the rabbit

1976 • 49 citations

Possible mechanism of success of an allotransplantation in nature: Mammalian pregnancy

1980 • 49 citations

Uteroglobin-like antigen in the male genital tract secretions

1975 • 48 citations

Modulation of Cellular Response to Antigens by Uteroglobin and Transglutaminase

1988 • 47 citations

Advances in Post-Translational Modifications of Proteins and Aging

1988 • 46 citations

Uterine secretion-like proteins in the seminal plasma of the rabbit

1976 • 46 citations

Ultrastructural localization of uteroglobin immunoreactivity in rabbit lung and endometrium, and rat ventral prostate

1985 • 44 citations

Partial Characterization of a Uteroglobin-Like Protein in the Human Uterus and Its Temporal Relationship to Prostaglandin Levels in This Organ*

1988 • 44 citations

Protein Composition of Human Uterine Fluid

1975 • 44 citations

Amino acid sequence of a progesterone-binding protein.

1978 • 43 citations

Analysis of Human Uterine Fluid Protein

1972 • 40 citations

Role of phospholipase A2 in the stimulation of sponge cell proliferation by homologous lectin

1989 • 40 citations

Repeating sequence homologies in the p36 target protein of retroviral protein kinases and lipocortin the p37 inhibitor of phospholipase A₂

1986 • 39 citations

Homology between rabbit uteroglobin and the rat seminal vesicle sperm-binding protein: Prediction of structural features of glutamine substrates for transglutaminase

1987 • 37 citations

Application of enantiomeric 2-sn-phosphatidylcholines in interfacial enzyme kinetics of lipolysis

1976 • 36 citations

Inhibition of thrombin-induced platelet aggregation by uteroglobin

1987 • 36 citations

Uteroglobin Messenger Ribonucleic Acid: Localization in Rabbit Uterus and Lung byin SituHybridization

1986 • 35 citations

Expression of a Uteroglobin-Like Protein in Human Prostate

1988 • 32 citations

Detection of a rabbit uteroglobin-like protein in human neonatal tracheobronchial washings

1988 • 31 citations

Human Uterine Fluid Proteins: Gel Electrophoretic Pattern and Progesterone-Binding Properties

1977 • 31 citations

Anti-inflammatory effects of vasocortin and nonapeptide fragments of uteroglobin and lipocortin I (antiflammins)

1990 • 31 citations

N-terminal sequences of uteroglobin and its precursor

1979 • 29 citations

Differential Regulation of a Low-Molecular-Weight Protein in Oviductal and Uterine Fluids by Ovarian Hormones¹

1974 • 28 citations

Identification of a uteroglobin-like antigen in human uterine washings

1986 • 27 citations

Modification of Phospholipase C and Phospholipase A2 Activities during Poliovirus Infection

1989 • 26 citations

Novel peptides derived from a region of local homology between uteroglobin and lipocortin-1 inhibit platelet aggregation and secretion

1989 • 26 citations

Inhibition of phospholipase A2 activity of guinea-pig alveolar macrophages by lipocortin-like proteins purified from mice lung

1988 • 26 citations

Uteroglobin and the accumulation of progesterone in the uterine lumen of the rabbit

1981 • 25 citations

Detection of a uteroglobin-like phospholipase A2 inhibitory protein in the circulation of rabbits

1989 • 22 citations

Asthma, physiology, immunopharmacology, and treatment : second international symposium

1977 • 13 citations

ROLE OF UTEROGLOBIN AND TRANSGLUTAMINASE IN SELF AND NON‐SELF RECOGNITION DURING REPRODUCTION IN THE RABBIT

1982 • 9 citations

4th international symposium on the immunology and immunopathology of the eye

1984 • 2 citations