Towards a transgenic mouse model of sickle cell disease: hemoglobin SAD.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes

1963 • 4,433 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 2,165 citations

Hemoglobin: Molecular, Genetic and Clinical Aspects.

1986 • 1,005 citations

DETERMINATION OF DENSITY DISTRIBUTION OF RED CELL POPULATION.

1964 • 385 citations

Globin Chain Electrophoresis: a New Approach to the Determination of the ^Gγ/^Aγ Ratio in Fetal Haemoglobin and to Studies of Globin Synthesis

1980 • 383 citations

Isoelectric focusing of human hemoglobin: its application to screening, to the characterization of 70 variants, and to the study of modified fractions of normal hemoglobins

1978 • 358 citations

Beyond hemoglobin polymerization: the red blood cell membrane and sickle disease pathophysiology

1991 • 333 citations

Separation of Human Hemoglobins by Deae-Cellulose Chromatography using Glycine-Kcn-Nacl Developers

1976 • 272 citations

Allosteric Effects in Haemoglobin

1982 • 246 citations

Molecular analysis of the human beta-globin locus activation region.

1989 • 218 citations

Delay Time of Hemoglobin S Polymerization Prevents Most Cells from Sickling in Vivo

1987 • 212 citations

Allosteric Effects in Haemoglobin

1982 • 205 citations

Human Sickle Hemoglobin in Transgenic Mice

1990 • 131 citations

Refined crystal structure of deoxyhemoglobin S. II. Molecular interactions in the crystal.

1985 • 129 citations

A transgenic mouse model of sickle cell disorder

1990 • 105 citations

Hemoglobin S Antilles: a variant with lower solubility than hemoglobin S and producing sickle cell disease in heterozygotes.

1986 • 100 citations

Correction of Murine β-Thalassemia by Gene Transfer into the Germ Line

1986 • 93 citations

Hemoglobin O Arab in Four Negro Families and Its Interaction with Hemoglobin S and Hemoglobin C

1970 • 91 citations

Hypoxia-induced in vivo sickling of transgenic mouse red cells.

1991 • 56 citations

A study of membrane protein defects and α hemoglobin chains of red blood cells in human β thalassemia

1989 • 47 citations

Nucleation-controlled aggregation of deoxyhemoglobin S. Participation of hemoglobin F in the aggregation of deoxyhemoglobin S in concentrated phosphate buffer.

1980 • 42 citations

Facilitation of Hb S polymerization by the substitution of Glu for Gln at beta 121.

1988 • 32 citations

Hematology of a Murine β‐Thalassemia: A Longitudinal Study^a

1985 • 29 citations

Mouse beta thalassemia, a model for the membrane defects of erythrocytes in the human disease

1990 • 29 citations

Ion Content and Transport and the Regulation of Volume in Sickle Cells

1989 • 22 citations

Introduction and expression of the human Bs-globin gene in transgenic mice.

1988 • 17 citations

HB Bruxelles: α2^Aβ₂41 or 42(C7 or CD1) Phe Deleted

1989 • 13 citations

Effect of the beta 73 amino acid on the hydrophobicity, solubility, and the kinetics of polymerization of deoxyhemoglobin S.

1987 • 11 citations

Functional and NMR studies of Hb sassari (); role of the inter-subunit contacts in the affinity control of human hemoglobin

1990 • 5 citations