Low toxicity of nitric oxide against endothelial cells under physiological oxygen partial pressures

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Free Radicals in Biology and Medicine

1990 • 4,962 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide

1991 • 2,215 citations

Nitric oxide: A cytotoxic activated macrophage effector molecule

1988 • 2,050 citations

Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase

1994 • 1,026 citations

Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase

1987 • 896 citations

Nitric Oxide Inhibits Electron Transfer and Increases Superoxide Radical Production in Rat Heart Mitochondria and Submitochondrial Particles

1996 • 726 citations

Complexes of ^.NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects

1991 • 724 citations

Control of coronary vascular tone by nitric oxide.

1990 • 713 citations

H2O2 release from human granulocytes during phagocytosis. I. Documentation, quantitation, and some regulating factors.

1975 • 653 citations

Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase

1995 • 540 citations

The Simultaneous Generation of Superoxide and Nitric Oxide Can Initiate Lipid Peroxidation in Human Low Density Lipoprotein

1992 • 460 citations

Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes

1991 • 395 citations

Tyrosine Modification by Reactive Nitrogen Species: A Closer Look

1995 • 371 citations

Reactions of nitrogen dioxide in aqueous model systems: Oxidation of tyrosine units in peptides and proteins

1985 • 333 citations

Nitric Oxide Potently and Reversibly Deenergizes Mitochondria at Low Oxygen Tension

1994 • 324 citations

Time course and mechanism of oxidative stress and tissue damage in rat liver subjected to in vivo ischemia-reperfusion.

1993 • 295 citations

Continuous Monitoring of Nitric Oxide Release from Human Umbilical Vein Endothelial Cells

1993 • 192 citations

A Sensitive Method for the Estimation of Hydrogen Peroxide in Biological Materials

1955 • 181 citations

Direct and indirect effects of nitric oxide in chemical reactions relevant to biology

1996 • 181 citations

Hypoxia, reactive oxygen, and cell injury

1989 • 171 citations

Oxygen-Dependent Regulation of Mitochondrial Energy Metabolism by Nitric Oxide

1995 • 156 citations

Regulation of endothelial cell glyceraldehyde-3-phosphate dehydrogenase expression by hypoxia.

1994 • 151 citations

The suppression of the N-nitrosating reaction by chlorogenic acid

1995 • 145 citations

Interaction of nitrogen dioxide with human plasma Antioxidant depletion and oxidative damage

1992 • 141 citations

Nitric oxide/nucleophile complexes inhibit the in vitro proliferation of A375 melanoma cells via nitric oxide release.

1993 • 137 citations

Cytotoxicity of nitric oxide in Fu5 rat hepatoma cells: evidence for co-operative action with hydrogen peroxide

1993 • 127 citations

Nitric oxide/nucleophile complexes: a unique class of nitric oxide-based vasodilators.

1993 • 122 citations

Inhibition of superoxide and nitric oxide release and protection from reoxygenation injury by ebselen in rat kupffer cells

1992 • 98 citations

Nitric-Oxide Kills Hepatocytes by Mobilizing Mitochondrial Calcium

1994 • 94 citations

Loss of α‐tocopherol upon exposure to nitric oxide or the sydnonimine SIN‐1

1993 • 86 citations

Reoxygenation Injury in Rat Hepatocytes: Mediation by O^Ө₂/H₂O₂. Liberated by Sources other than Xanthine Oxidase

1991 • 83 citations

Endothelial Damage Induced by Nitric Oxide: Synergism with Reactive Oxygen Species

1995 • 72 citations

Hydrogen peroxide at low concentrations strongly enhances the inhibitory effect of nitric oxide on platelets

1995 • 64 citations

Stimulation of Glyceraldehyde-3-Phosphate Dehydrogenase mRNA Levels by Endogenous Nitric Oxide in Cytokine-Activated Endothelium

1995 • 61 citations

Enhanced release of nitric oxide causes increased cytotoxicity of S-nitroso-N-acetyl-<scp>dl</scp>-penicillamine and sodium nitroprusside under hypoxic conditions

1996 • 58 citations

ENERGY-DEPENDENT INJURY TO CULTURED SINUSOIDAL ENDOTHELIAL CELLS OF THE RAT LIVER IN UW SOLUTION

1993 • 54 citations

NO2-induced DNA single strand breaks are inhibited by antioxidative vitamins in V79 cells

1993 • 48 citations

Determination of selectivity of reactive nitrogen oxide species for various substrates

1996 • 42 citations