Surface Carbohydrate Alterations of Mutant Mammalian Cells Selected for Resistance to Plant Lectins

The Interactions of Lectins with Animal Cell Surfaces

1974 • 996 citations

On the nature of hereditable variation in cultured somatic cells

1976 • 497 citations

Proposal for a common oligosaccharide intermediate in the synthesis of membrane glycoproteins

1977 • 489 citations

Mechanism of action of the toxic lectins abrin and ricin

1974 • 443 citations

Fractionation of Glycopeptides by Affinity Column Chromatography on Concanavalin A-Sepharose1

1975 • 428 citations

Processing of high mannose oligosaccharides to form complex type oligosaccharides on the newly synthesized polypeptides of the vesicular stomatitis virus G protein and the IgG heavy chain.

1978 • 362 citations

Metabolic Conjugation and Metabolic Hydrolysis

1970 • 325 citations

The synthesis of complex-type oligosaccharides. III. Identification of an alpha-D-mannosidase activity involved in a late stage of processing of complex-type oligosaccharides

1978 • 282 citations

Selection and characterization of eight phenotypically distinct lines of lectin-resistant chinese hamster ovary cells

1975 • 280 citations

Deficient uridine diphosphate-N-acetylglucosamine:glycoprotein N-acetylglucosaminyltransferase activity in a clone of Chinese hamster ovary cells with altered surface glycoproteins.

1975 • 227 citations

Isolation of wheat germ agglutinin-resistant clones of Chinese hamster ovary cells deficient in membrane sialic acid and galactose.

1977 • 223 citations

Chinese hamster ovary cells selected for resistance to the cytotoxicity of phytohemagglutinin are deficient in a UDP-N-acetylglucosamine--glycoprotein N-acetylglucosaminyltransferase activity.

1975 • 222 citations

Interaction of immunoglobulin glycopeptides with concanavalin A.

1975 • 192 citations

Control of glycoprotein synthesis. Lectin-resistant mutant containing only one of two distinct N-acetylglucosaminyltransferase activities present in wild type Chinese hamster ovary cells.

1977 • 161 citations

The Biology of Oncogenic Viruses.

1973 • 160 citations

Complementation between mutants of CHO cells resistant to a variety of plant lectins

1977 • 159 citations

The synthesis and properties of T25 glycoprotein in thy-1-negative mutant lymphoma cells

1978 • 158 citations

Studies on the mechanism of the adenosylcobalamin-dependent diol dehydrase reaction by the use of analogs of the coenzyme.

1977 • 156 citations

Specific changes in the oligosaccharide moieties of VSV grown in different lectin-resistant CHO cells

1978 • 133 citations

The Nature of the Cell Surface Receptor Site for Lens culinaris Phytohemagglutinin

1971 • 127 citations

Chemical nature of the receptor site for various phytomitogens

1972 • 126 citations

Isolation of a Clone of Chinese Hamster Ovary Cells Deficient in Plant Lectin-Binding Sites

1974 • 120 citations

Contact-Inhibited Revertant Cell Lines Isolated from Simian Virus 40-Transformed Cells III. Concanavalin A-Selected Revertant Cells

1972 • 113 citations

Ricin resistance in baby hamster kidney cells

1975 • 100 citations

Structure of the altered oligosaccharide present in glycoproteins from a clone of Chinese hamster ovary cells deficient in N-acetylglucosaminyltransferase activity.

1978 • 93 citations

Growth of Enveloped RNA Viruses in a Line of Chinese Hamster Ovary Cells with Deficient N -Acetyl-glucosaminyltransferase Activity

1976 • 92 citations

Variants of hamster fibroblasts resistant to Ricinus communis toxin (ricin)

1976 • 85 citations

Role of cell surface carbohydrates and proteins in cell behavior: studies on the biochemical reversion of an N-acetylglucosamine-deficient fibroblast mutant.

1977 • 85 citations

Stable alterations at the cell membrane of Chinese hamster ovary cells resistant to the cytotoxicity of phytohemagglutinin

1975 • 83 citations

Binding, Uptake and Degradation of the Toxic Proteins Abrin and Ricin by Toxin‐Resistant Cell Variants

1978 • 82 citations

Structure of Seven Oligosaccharides Excreted in the Urine of a Patient with Sandhoff's Disease (GM₂ Gangliosidosis‐Variant O)

1977 • 80 citations

Differential involvement of cell surface sialic acid residues in wheat germ agglutinin binding to parental and wheat germ agglutinin-resistant Chinese hamster ovary cells.

1980 • 80 citations

EVIDENCE FOR PLEIOTROPIC CHANGES IN LINES OF CHINESE HAMSTER OVARY CELLS RESISTANT TO CONCANAVALIN A AND PHYTOHEMAGGLUTININ-P

1973 • 76 citations

Metabolic Conjugation and Metabolic Hydrolysis

1973 • 76 citations

Mutants of Balb/c 3T3 fibroblasts defective in adhesiveness to substratum: evidence for alteration in cell surface proteins.

1976 • 74 citations

Studies on Surface Antigen Variants. Isolation of Two Complementary Variants for Thy 1.22

1973 • 73 citations

Isolation and characterization of two mouse L cell lines resistant to the toxic lectin ricin

1976 • 72 citations

A simple method for the isolation of neutral glycopeptides by affinity chromatography

1976 • 68 citations

Growth and biochemical characteristics of a detachment variant of CHO cells

1977 • 64 citations

Mutants of mouse fibroblasts altered in the synthesis of cell surface glycoproteins. Preliminary evidence for a defect in the acetylation of glucosamine 6-phosphate.

1977 • 64 citations

Drug‐resistant mutants of chinese hamster ovary cells possess an altered cell surface carbohydrate component

1976 • 64 citations

THE BIOSYNTHESIS OF ANIMAL GLYCOPROTEINS

1973 • 59 citations

Thy-1 variants of mouse lymphomas: biochemical characterization of the genetic defect

1975 • 58 citations

A concanavalin A-resistant Chinese hamster ovary cell line is deficient in the synthesis of [3H]glucosyl oligosaccharide-lipid.

1979 • 58 citations

Derivation of Lymphoma Variants With Reduced Sensitivity to Plant Lectins2

1974 • 56 citations

Effects of neuraminidase on lectin binding by wild-type and ricin-resistant strains of hamster fibroblasts

1977 • 49 citations

Variants of Simian Virus 40-Transformed 3T3 Cells That Are Resistant to Concanavalin A

1973 • 46 citations

Correlation Between the Mobility of Inner Plasma Membrane Structure and Agglutination by Concanavalin A in Two Cell Lines of MOPC 173 Plasmocytoma Cells

1974 • 45 citations

Glycoprotein synthesis in a temperature‐sensitive Chinese hamster cell cycle mutant

1977 • 44 citations

Reduced synthesis of [14C]mannosyl oligosaccharide-lipid by membranes prepared from concanavalin A-resistant Chinese hamster ovary cells.

1977 • 43 citations

Altered Cell surface glycoproteins in phytohemagglutinin-resistant mutants of Chinese hamster ovary cells

1975 • 43 citations

Membrane Mutants of Mammalian Cells in Culture

1978 • 42 citations

Selective loss of wheat germ agglutinin binding to agglutinin-resistant mutants of Chinese hamster ovary cells.

1977 • 41 citations

Colchicine permeation is required for inhibition of concanavalin A capping in Chinese hamster ovary cells.

1975 • 35 citations

Cell surface receptors and their dynamics on toxin‐treated malignant cells

1976 • 33 citations

Lipid‐saccharide intermediates and glycoprotein biosynthesis in a temperature‐sensitive Chinese hamster cell mutant

1979 • 32 citations

Induction of ornithine decarboxylase activity in a temperature-sensitive cell cycle mutant of Chinese hamster cells.

1978 • 27 citations

Cell-Surface Changes in a Ricinus communis Toxin (Ricin)-Resistant Variant of a Murine Lymphoma2

1977 • 26 citations

Characteristics of concanavalin A‐resistant Chinese hamster ovary cells and certain revertants

1979 • 25 citations

The concanavalin a binding properties of concanavalin A-resistant and -sensitive hamster cell lines

1977 • 24 citations

Effects of wheat germ agglutinin on membrane transport

1977 • 24 citations

Lectin Receptors and Lectin Resistance in Chinese Hamster Ovary Cells

1977 • 24 citations

Selection and characterization of chinese hamster ovary cells resistant to the cytotoxicity of lectins

1976 • 23 citations

Mapping of sites on the surface membrane of mammalian cells

1972 • 19 citations

A mutant fibroblast cell line defective in glycoprotein synthesis due to a deficiency of glucosamine phosphate acetyltransferase

1978 • 17 citations

Mammalian concanavalin A-resistant cells contain altered cell surface glycoproteins

1978 • 16 citations

Concanavalin A as a selective agent in tissue culture for temperature-sensitive hamster cell lines

1975 • 16 citations

Analysis of Thy-1 variants of murine lymphoma cells

1977 • 12 citations