Structure, Function, and Regulation of Mammalian Pyruvate Dehydrogenase Complex

α-KETO ACID DEHYDROGENASE COMPLEXES, X. REGULATION OF THE ACTIVITY OF THE PYRUVATE DEHYDROGENASE COMPLEX FROM BEEF KIDNEY MITOCHONDRIA BY PHOSPHORYLATION AND DEPHOSPHORYLATION

1969 • 669 citations

Multienzyme complexes

1974 • 655 citations

Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase

1972 • 519 citations

Generation by Insulin of a Chemical Mediator That Controls Protein Phosphorylation and Dephosphorylation

1979 • 373 citations

Regulation of pyruvate dehydrogenase kinase and phosphatase by acetyl-CoA/CoA and NADH/NAD ratios

1975 • 303 citations

Sites of phosphorylation on pyruvate dehydrogenase from bovine kidney and heart

1978 • 283 citations

α-Keto acid dehydrogenase complexes

1972 • 278 citations

Interconvertible Enzyme Cascades in Cellular Regulation

1980 • 257 citations

Superiority of interconvertible enzyme cascades in metabolic regulation: Analysis of multicyclic systems

1977 • 173 citations

Function of calcium ions in pyruvate dehydrogenase phosphatase activity

1972 • 157 citations

α-Keto Acid Dehydrogenase Complexes

1973 • 149 citations

Superiority of interconvertible enzyme cascades in metabolic regulation: analysis of monocyclic systems.

1977 • 136 citations

Subunit structure of dihydrolipoyl transacetylase component of pyruvate dehydrogenase complex from Escherichia coli

1979 • 122 citations

Purification and Characterization of Pyruvate‐Dehydrogenase Phosphatase from Pig‐Heart Muscle

1972 • 110 citations

Subunit structure of dihydrolipoyl transacetylase component of pyruvate dehydrogenase complex from bovine heart.

1981 • 100 citations

Control of pyruvate dehydrogenase in the perfused rat heart by the intracellular concentration of acetyl-coenzyme A.

1964 • 99 citations

Insulin stimulation of pyruvate dehydrogenase in an isolated plasma membrane-mitochondrial mixture occurs by activation of pyruvate dehydrogenase phosphatase.

1980 • 95 citations

Regulation of pig heart pyruvate dehydrogenase by phosphorylation. Studies on the subunit and phosphorylation stoicheiometries

1978 • 93 citations

Amino acid sequences around the sites of phosphorylation in the pig heart pyruvate dehydrogenase complex

1979 • 90 citations

Phosphorylation of additional sites on pyruvate dehydrogenase inhibits its re-activation by pyruvate dehydrogenase phosphate phosphatase

1978 • 89 citations

Pyruvate dehydrogenase and the hormonal regulation of fat synthesis in mammalian tissues

1978 • 76 citations

Monovalent cation requirement for ADP inhibition of pyruvate dehydrogenase kinase

1974 • 75 citations

Function of phosphorylation sites on pyruvate dehydrogenase

1979 • 73 citations

Peptides derived from pyruvate dehydrogenase as substrates for pyruvate dehydrogenase kinase and phosphatase

1977 • 55 citations

Lipoic acid content of dihydrolipoyl transacylases determined by isotope dilution analysis

1980 • 50 citations

Binding of thiamin thiazolone pyrophosphate to mammalian pyruvate dehydrogenase and its effects on kinase and phosphatase activities

1977 • 49 citations

The multienzyme alpha-keto acid dehydrogenase complexes.

1968 • 43 citations

Inactivation and Disassembly of the Pyruvate Dehydrogenase Multienzyme Complex from Bovine Kidney by Limited Proteolysis with an Enzyme from Rat Liver

1979 • 33 citations

Role of multi‐site phosphorylation in regulation of pig heart pyruvate dehydrogenase phosphatase

1979 • 27 citations

Purification, Properties, and Subunit Composition of Pig Heart Lipoate Acetyltransferase<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1975 • 20 citations

Untersuchungen zur struktur der pyruvatdehydrogenase aus schweineherzmuskel

1971 • 19 citations

Mammalian lipoate acetyltransferase: molecular weight determination by gel filtration in the presence of guanidinium chloride

1980 • 17 citations

Structure, Function and Regulation of the Mammalian Pyruvate Dehydrogenase Complex

1974 • 16 citations

STRUCTURE, FUNCTION AND REGULATION OF THE MAMMALIAN PYRUVATE DEHYDROGENASE COMPLEX

1980 • 16 citations

Enhanced dissociation of pyruvate dehydrogenase from the pyruvate dehydrogenase complex following phosphorylation and regulatory implications

1979 • 13 citations

Inactivation of pig heart pyruvate dehydrogenase complex by adenosine‐5′‐O(3‐thiotriphosphate)

1980 • 8 citations

Evidence for two‐domain subunit structure of kidney lipoate acetyltransferase

1980 • 7 citations