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Abstract

References (70)

Clinical classification of pulmonary hypertension

2004 • 1,915 citations

Treatment of Pulmonary Arterial Hypertension

2004 • 1,673 citations

Cellular and molecular pathobiology of pulmonary arterial hypertension

2004 • 1,521 citations

Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology.

2004 • 1,041 citations

Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial

2008 • 910 citations

Medical Therapy For Pulmonary Arterial Hypertension

2004 • 853 citations

Bosentan Therapy in Patients With Eisenmenger Syndrome

2006 • 811 citations

Pathologic assessment of vasculopathies in pulmonary hypertension

2004 • 697 citations

The Eisenmenger Syndrome: I

1958 • 607 citations

Second natural history study of congenital heart defects. Results of treatment of patients with ventricular septal defects.

1993 • 557 citations

Eisenmenger syndrome. Factors relating to deterioration and death

1998 • 522 citations

Management of Grown Up Congenital Heart Disease

2003 • 512 citations

Long-Term Prostacyclin for Pulmonary Hypertension With Associated Congenital Heart Defects

1999 • 510 citations

Imatinib for the Treatment of Pulmonary Arterial Hypertension

2005 • 466 citations

Comparison of the hemodynamics and survival of adults with severe primary pulmonary hypertension or Eisenmenger syndrome.

1996 • 435 citations

Medical Therapy for Pulmonary Arterial Hypertension

2007 • 422 citations

Pulmonary Vascular Disease in Adults With Congenital Heart Disease

2007 • 387 citations

Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension

2005 • 355 citations

Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension

2003 • 330 citations

Early effects of tissue-type plasminogen activator added to conventional therapy on the culprit coronary lesion in patients presenting with ischemic cardiac pain at rest. Results of the Thrombolysis in Myocardial Ischemia (TIMI IIIA) Trial.

1993 • 322 citations

The Eisenmenger Syndrome in Adults

1998 • 307 citations

A randomized, placebo-controlled, double-blind, crossover study to evaluate the efficacy of oral sildenafil therapy in severe pulmonary artery hypertension

2006 • 257 citations

Longer-term bosentan therapy improves functional capacity in Eisenmenger syndrome: Results of the BREATHE-5 open-label extension study

2007 • 244 citations

Activation of Soluble Guanylate Cyclase Reverses Experimental Pulmonary Hypertension and Vascular Remodeling

2006 • 214 citations

Second natural history study of congenital heart defects.

1993 • 211 citations

Short- and Long-Term Effects of Inhaled Iloprost Therapy in Children With Pulmonary Arterial Hypertension

2008 • 203 citations

Pulmonary Arterial Thrombosis in Eisenmenger Syndrome Is Associated With Biventricular Dysfunction and Decreased Pulmonary Flow Velocity

2007 • 178 citations

Heart–lung or lung transplantation for Eisenmenger syndrome

2002 • 161 citations

Phosphodiesterase 1 Upregulation in Pulmonary Arterial Hypertension

2007 • 138 citations

Usefulness of epoprostenol therapy in the severely ill adolescent/adult with Eisenmenger physiology

2003 • 138 citations

Phosphodiesterase-5 Inhibitor in Eisenmenger Syndrome

2006 • 137 citations

Long-term oral bosentan treatment in patients with pulmonary arterial hypertension related to congenital heart disease: a 2-year study

2006 • 122 citations

Effects of chronic sildenafil in patients with Eisenmenger syndrome versus idiopathic pulmonary arterial hypertension

2006 • 122 citations

Long-term effect of bosentan in adults versus children with pulmonary arterial hypertension associated with systemic-to-pulmonary shunt: Does the beneficial effect persist?

2007 • 117 citations

Safety and tolerability of bosentan in adults with Eisenmenger physiology

2004 • 109 citations

Flap Valve Double Patch Closure of Ventricular Septal Defects in Children With Increased Pulmonary Vascular Resistance

2004 • 101 citations

Long-term safety, tolerability and efficacy of bosentan in adults with pulmonary arterial hypertension associated with congenital heart disease

2007 • 96 citations

Systemic Endothelial Dysfunction in Adults With Cyanotic Congenital Heart Disease

2005 • 96 citations

Adult patients with congenital heart disease and pulmonary arterial hypertension: First open prospective multicenter study of bosentan therapy

2005 • 91 citations

Microvascular Regeneration in Established Pulmonary Hypertension by Angiogenic Gene Transfer

2006 • 88 citations

Long term effects of bosentan treatment in adult patients with pulmonary arterial hypertension related to congenital heart disease (Eisenmenger physiology): safety, tolerability, clinical, and haemodynamic effect

2006 • 86 citations

Heart-lung transplantation for Eisenmenger syndrome: early and long-term results

2001 • 85 citations

Eisenmenger's syndrome: Current management

2002 • 77 citations

Reversal of pulmonary hypertension and subsequent repair of atrial septal defect after treatment with continuous intravenous epoprostenol

2005 • 76 citations

Responsiveness to inhaled nitric oxide is a predictor for mid-term survival in adult patients with congenital heart defects and pulmonary arterial hypertension

2004 • 73 citations

Role of oral sildenafil in severe pulmonary arterial hypertension: Clinical efficacy and dose response relationship

2006 • 71 citations

Residual pulmonary vasoreactivity to inhaled nitric oxide in patients with severe obstructive pulmonary hypertension and Eisenmenger syndrome

2001 • 71 citations

Initial experience with bosentan therapy in patients with the Eisenmenger syndrome

2004 • 69 citations

Inhaled Iloprost Reverses Vascular Remodeling in Chronic Experimental Pulmonary Hypertension

2005 • 69 citations

Comparison of acute hemodynamic effects of aerosolized and intravenous iloprost in secondary pulmonary hypertension in children with congenital heart disease

2003 • 63 citations

First experience with an oral combination therapy using bosentan and sildenafil for pulmonary arterial hypertension

2006 • 61 citations

Efficacy of Bosentan in a Small Cohort of Adult Patients With Pulmonary Arterial Hypertension Related to Congenital Heart Disease

2006 • 47 citations

Advanced therapy may delay the need for transplantation in patients with the Eisenmenger syndrome

2006 • 44 citations

Pulmonary Neovascularity

2005 • 42 citations

Sildenafil therapy for pulmonary arterial hypertension associated with atrial septal defects

2006 • 37 citations

Successful reversal of pulmonary hypertension in Eisenmenger complex.

1997 • 33 citations

Pulmonary vascular resistance during exercise late after repair of large ventricular septal defects

1995 • 32 citations

Pulmonary arterial hypertension related to congenital heart disease

2015 • 29 citations

Use of Long-Term Combined Therapy With Inhaled Iloprost and Oral Sildenafil in an Adult Patient With Eisenmenger Syndrome

2005 • 22 citations

Beraprost Therapy in Children with Pulmonary Hypertension Secondary to Congenital Heart Disease

2005 • 17 citations

[Comparative studies of hemodynamics under prostacyclin and nifedipine in patients with Eisenmenger syndrome].

1995 • 15 citations

Valved Patch for Ventricular Septal Defect with Pulmonary Arterial Hypertension

2006 • 13 citations

Treatment of patients with Eisenmenger's syndrome with Bosentan

2007 • 13 citations

Effects Of Sildenafil Treatment In Patients With Pulmonary Hypertension Associated With Congenital Cardiac Shunts

2010 • 9 citations

Long-term effect of bosentan in paediatric versus adult patients with pulmonary arterial hypertension associated with systemic-to-pulmonary shunt : does the beneficial effect persist?

2007 • 8 citations

Late banding operation in children with ventricular septal defect and pulmonary arterial hypertension.

1975 • 5 citations

A 38-year-old man with pulmonary hypertension, who had undergone atrial septal closure 26 years previously.

2003 • 4 citations

Anomalous origin of the main stem of the left coronary artery from the pulmonary trunk presenting with left ventricular hypertrophy

2007 • 3 citations

Abstract 2108: Sitaxsentan Treatment In Patients With Eisenmenger Syndrome

2007 • 2 citations

[Long-term experience with trerpostinil infusion treatment in patients with pulmonary arterial hypertension in the Czech Republic].

2007 • 1 citations

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