CYTOTOXIC CHEMOTHERAPY FOR ADVANCED RENAL CELL CARCINOMA

Expression of Multidrug Resistance Gene in Human Cancers

1989 • 1,305 citations

Cancer statistics, 1992

1992 • 540 citations

Inhibition of protein kinase C by tamoxifen.

1985 • 464 citations

Prognostic factors for survival in patients with recurrent or metastatic renal cell carcinoma.

1988 • 340 citations

Intrinsic drug resistance in human kidney cancer is associated with expression of a human multidrug-resistance gene.

1987 • 225 citations

Current status of the therapy of advanced renal carcinoma

1977 • 180 citations

Hormonal therapy and chemotherapy of renal-cell carcinoma.

1983 • 171 citations

Recombinant interferon alfa-2a with or without vinblastine in metastatic renal cell carcinoma: Results of a European multi-center phase III study

1992 • 131 citations

Effect of autolymphocyte therapy on survival and quality of life in patients with metastatic renal-cell carcinoma

1990 • 123 citations

Circadian-shaped infusions of floxuridine for progressive metastatic renal cell carcinoma.

1990 • 121 citations

The EORTC early clinical trials cooperative group experience with 5-aza-2′-deoxycytidine (NSC 127716) in patients with colo-rectal, head and neck, renal carcinomas and malignant melanomas

1987 • 119 citations

Treatment of metastatic renal cell carcinoma with coumarin (1,2-benzopyrone) and cimetidine: a pilot study.

1987 • 106 citations

Vinblastine fails to improve response of renal cancer to interferon alfa-n1: high response rate in patients with pulmonary metastases.

1991 • 105 citations

Circadian patterning of continuous floxuridine infusion reduces toxicity and allows higher dose intensity in patients with widespread cancer.

1989 • 100 citations

Chemotherapy of renal cell carcinoma: 1983-1989.

1989 • 94 citations

Phase II study of coumarin and cimetidine in patients with metastatic renal cell carcinoma.

1990 • 94 citations

Phase II study of 9-hydroxy-2N-methylellipticinium acetate

1984 • 65 citations

Immunoanatomic dissection of the human urinary tract by monoclonal antibodies.

1984 • 63 citations

Chemotherapy of adenocarcinoma of the kidney

1973 • 62 citations

Immunoanatomic distribution of cytostructural and tissue-associated antigens in the human urinary tract.

1987 • 61 citations

Multidrug Resistance: P-glycoprotein and Its Allies--The Elusive Foes

1989 • 61 citations

Mechanisms and Modulation of Multidrug Resistance in Primary Human Renal Cell Carcinoma

1990 • 57 citations

Phase II Study of Interferon-α and Chemotherapy (5-Fluorouracil and Mitomycin C) in Metastatic Renal Cell Cancer

1992 • 57 citations

Phase II Trial of Taxol in Patients with Metastatic Renal Cell Carcinoma

1991 • 56 citations

Phase II trials of 5-day vinblastine infusion (NSC 49842), L-alanosine (NSC 153353), acivicin (NSC 163501), and aminothiadiazole (NSC 4728) in patients with recurrent or metastatic renal cell carcinoma

1988 • 56 citations

The Current Status of Chemotherapy for Advanced Renal Carcinoma

1967 • 52 citations

Analysis of a mouse monoclonal antibody that reacts with a specific region of the human proximal tubule and subsets renal cell carcinomas.

1989 • 52 citations

Phase II study of combining vinblastine and cyclosporin-A to circumvent multidrug resistance in renal cell cancer

1991 • 52 citations

Immunohistologic Dissection of the Human Kidney Using Monoclonal Antibodies

1985 • 51 citations

Treatment of advanced renal cell cancer with recombinant interferon alpha as a single agent and in combination with medroxyprogesterone acetate

1988 • 49 citations

Circadian continuous chemotherapy of renal cell carcinoma with an implantable, programmable infusion pump

1990 • 48 citations

A pilot study of suramin in the treatment of metastatic renal cell carcinoma

1991 • 47 citations

Expression of several resistance mechanisms in untreated human kidney and lung carcinomas

1993 • 37 citations

Circadian Infusion of Floxuridine in Patients with Metastatic Renal Cell Carcinoma

1991 • 37 citations

New Potent Verapamil Derivatives that Reverse Multidrug Resistance in Human Renal Carcinoma Cells and in Transgenic Mice Expressing the Human MDR 1 Gene

1991 • 36 citations

Inhibition of human renal cancer by monoclonal antibody targeted methotrexate-containing liposomes in an ascites tumor model

1991 • 35 citations

Cimetidine and Coumarin Therapy of Renal Cell Carcinoma

1991 • 31 citations

Immunotherapy of Metastatic Renal Cell Carcinoma with Polyinosinic-Polycytidylic Acid

1987 • 31 citations

Monoclonal antibodies in urologic oncology

1987 • 29 citations

Intermittent regional infusion of chemotherapy for pancreatic adenocarcinoma

1982 • 27 citations

Phase II study of vindesine sulfate in the therapy for advanced renal carcinoma.

1977 • 25 citations

Estrogen, progesterone, and androgen-binding sites in renal cell carcinoma. Observations obtained in phase II trial of flutamide

1984 • 24 citations

Recombinant Interferon‐alpha with or without Vinblastine in Metastatic Renal Carcinoma Results of a Randomised Phase II Study

1989 • 23 citations

A Phase II study of high dose tamoxifen in progressive, metastatic renal cell

1992 • 23 citations

An EORTC phase II study of mitoxantrone in solid tumors and lymphomas

1984 • 22 citations

Phase II evaluation of didemnin B in advanced adenocarcinoma of the kidney

1992 • 21 citations

One versus 2 years of CMFVP adjuvant chemotherapy in axillary node-positive and estrogen receptor-negative patients: a Southwest Oncology Group study.

1993 • 21 citations

Phase II study of echinomycin in patients with advanced breast cancer: A report of cancer and leukemia group B protocol 8641

1991 • 20 citations

Phase II study of continuous 5-day vinblastine infusion in renal adenocarcinoma.

1984 • 20 citations

Phase-II trial of 4-demethoxydaunorubicin (DMDR) for advanced hypernephroma

1985 • 20 citations

Phase II trial of Didemnin B in patients with advanced renal cell carcinoma

1990 • 20 citations

Phase II trial of misonidazole (MISO) and cyclophosphamide (CYC) in metastatic renal cell carcinoma

1986 • 19 citations

High-Dose Cimetidine for the Treatment of Metastatic Renal Cell Carcinoma

1992 • 19 citations

Phase II study of lonidamine in patients with metastatic renal cell carcinoma: a National Cancer Institute of Canada Clinical Trials Group Study.

1986 • 18 citations

Phase I-II trial of a 5-day continuous infusion of vinblastine sulfate.

1984 • 18 citations

Interferon Alternating with Chemotherapy for Patients with Metastatic Renal Cell Carcinoma

1989 • 18 citations

Lonidamine versus high-dose tamoxifen in progressive, advanced renal cell carcinoma: results of an ongoing randomized phase II study.

1991 • 17 citations

Short report: Phase II trial of coumarin and cimetidine in advanced renal cell carcinoma

1990 • 17 citations

Phase I--II trial of methyl-GAG in the treatment of patients with metastatic renal adenocarcinoma.

1981 • 17 citations

Phase II study of 4'-epi-doxorubicin in metastatic renal cancer.

1982 • 17 citations

Misteltoe (Iscador) Therapy in Stage Iv Renal Adenocarcinoma: A Phase II study in patients with measurable lung metastases

1989 • 16 citations

Gallium 67 Scanning in Patients with Renal Cell Carcinoma

1973 • 16 citations

Mitoxantrone in advanced renal cancer: A phase II study in previously untreated patients from the EORTC Genito-Urinary Tract Cancer Cooperative Group

1984 • 15 citations

Twelve-year experience with chemotherapy in adult metastatic renal cell carcinoma at the Institut Gustave-Roussy.

1988 • 15 citations

Phase II Study of Five-Day Continuous Infusion of Vinblastine in Patients With Metastatic Renal-Cell Carcinoma

1987 • 15 citations

Phase II trial of elliptinium in advanced renal cell carcinoma and carcinoma of the breast.

1985 • 14 citations

Flexibility and efficacy of automatic continuous fluorodeoxyuridine infusion in metastases from a renal cell carcinoma

1991 • 14 citations

Phase II trial of fludarabine phosphate in advanced renal cell carcinoma: An Illinois Cancer Council study

1989 • 14 citations

Phase II trial of elliptinium in advanced renal cell carcinoma.

1985 • 14 citations

Phase I-II trial of gallium nitrate for advanced hypernephroma.

1984 • 13 citations

Evaluation of fludarabine phosphate in renal cell carcinoma: a Southwest Oncology Group Study.

1987 • 13 citations

Phase II evaluation of bisantrene in patients with renal cell carcinoma.

1982 • 12 citations

Phase II trial of PALA in hypernephroma and urinary bladder cancer.

1982 • 12 citations

Trimetrexate in advanced renal cell carcinoma

1992 • 12 citations

Phase II trial of trimetrexate in patients with advanced renal cell carcinoma

1989 • 11 citations

Phase II trial of 4ʼepi-adriamycin for advanced hypernephroma

1983 • 11 citations

Use of VM-26 as a single agent in the treatment of renal carcinoma.

1979 • 11 citations

DNA determinations for prognosis and therapy control in prostatic cancer.

1983 • 11 citations

Treatment of advanced adenocarcinoma of the kidney with ICRF-187: a Southeastern Cancer Study Group Trial.

1986 • 11 citations

Phase II evaluation of mitoxantrone in advanced renal cell carcinoma: a Southeastern Cancer Study Group Trial.

1986 • 10 citations

Phase II Trial of 5-Fluorouracil and High-Dose Folinic Acid in Advanced Renal Cell Cancer

1989 • 10 citations

Five-day infusion of fluorodeoxyuridine with high-dose oral leucovorin: a phase I study

1991 • 10 citations

Phase II study of sulofenur (LY186641) in measurable metastatic renal cancer

1992 • 10 citations

Evaluation of carboplatin (NSC 241240) in patients with recurrent or metastatic renal cell carcinoma

1990 • 9 citations

Phase II trial of 4ʼepi-adriamycin for advanced hypernephroma

1983 • 9 citations

Phase II trial of bisantrene for advanced hypernephroma.

1982 • 9 citations

An EORTC phase II study of methyl-glyoxal bis-guanylhydrazone in advanced renal cell cancer

1982 • 8 citations

Evaluation of deoxycoformycin in patients with advanced renal cell carcinoma

1992 • 8 citations

Teniposide in metastatic renal and bladder cancer: a Southwest Oncology Group Study.

1987 • 7 citations

Phase II trial of spirogermanium in advanced renal cell carcinoma: a Cancer and Leukemia Group B study.

1984 • 7 citations

Phase II evaluation of amonafide in renal cell carcinoma

1991 • 7 citations

Phase II trial of 10-deazaaminopterin for advanced hypernephroma.

1984 • 7 citations

Phase II studies of PCNU and bisantrene in advanced renal cell carcinoma.

1987 • 7 citations

Phase II study of 2′-deoxycoformycin in patients with renal cell carcinoma

1991 • 7 citations

Phase II clinical trial of mitoxantrone in patients with advanced renal cell carcinoma: a Southwest Oncology Group study.

1984 • 6 citations

Vindesine in advanced renal cancer. A study of the EORTC genito-urinary tract cancer cooperative group

1983 • 6 citations

Mitozolomide in advanced renal cancer

1989 • 6 citations

Therapy for advanced renal cell cancer with spirogermanium: a Southwest Oncology Group Study.

1987 • 6 citations

Ifosfamide chemotherapy of metastatic renal cell cancer.

1988 • 6 citations

Deoxyribonucleic Acid Content and Medroxyprogesterone Acetate Treatment in Metastatic Renal Cell Carcinoma

1989 • 6 citations

Twelve-Year Experience With Chemotherapy in Adult Metastatic Renal Cell Carcinoma at the Institut Gus-tave-Roussy

1988 • 6 citations

Evaluation of menogaril in renal cell carcinoma

1990 • 5 citations

Phase II trial of esorubicin (4′ deoxydoxorubicin) in cancers of the breast, colon, kidney, lung and melanoma

1986 • 5 citations

Phase II evaluation of aclacinomyin-A (NSC-208734) in adenocarcinoma of the kidney

1984 • 5 citations

Phase II trial of methyl-G (methylglyoxal bis-guanylhydrazone) in patients with metastatic renal cell carcinoma.

1981 • 5 citations

Phase II Trial of N-Methylformamide in Advanced Renal Cancer

1989 • 4 citations

Pilot phase II trial of amphotericin B and CCNU in renal and colorectal carcinomas

1986 • 4 citations

The effects of sex steroids on renal gene expression.

1989 • 4 citations

Phase II trial of esorubicin in the treatment of metastatic carcinoma of the kidney: a study of the Northern California Oncology Group.

1987 • 4 citations

Primary resistance of renal adenocarcinoma to 1,2,4-triglycidylurazol (TGU, NSC 332488), a new triexpoxide cytostatic agent — A phase II study of the EORTC early clinical trials group

1986 • 4 citations

Phase II Evaluation of 4ʼDeoxydoxorubicin in Advanced Renal Cell Carcinoma

1990 • 4 citations

FUNDAMENTAL STUDY OF ENDOCRINE THERAPY FOR RENAL CELL CARCINOMA

1980 • 4 citations

Evaluation of menogaril in renal cell carcinoma. A Southwest Oncology Group phase II study (8504).

1990 • 4 citations

Advances in chemotherapy for renal cell carcinoma.

1992 • 4 citations

Phase II evaluation of menogaril in patients with advanced hypernephroma

1991 • 4 citations

Phase II evaluation of bisantrene in patients with advanced renal cell carcinoma.

1985 • 3 citations

4′Deoxydoxorubicin in advanced renal cancer

1986 • 3 citations

Immunodiagnosis of renal cell carcinoma.

1990 • 3 citations

High dose AZQ in renal cancer

1986 • 3 citations

Alpha-Interferon and Oral Fluorouracil in the Treatment of Unremovable and/or Metastatic Renal Cancer

1991 • 2 citations

Phase II trial of diaziquone in advanced renal adenocarcinoma.

1984 • 2 citations

Phase II Trial of Methyl-gagand Melphalan in Metastatic Adult Renal Cell Carcinoma

1990 • 2 citations

Mitoguazone in advanced renal carcinoma: a phase II trial of the Southwest Oncology Group.

1983 • 2 citations

Ifosfamide Chemotherapy of Metastatic Renal Cell Cancer

1988 • 2 citations

Phase II trial of esorubicin in advanced renal carcinoma

1989 • 1 citations

The Effect of Verapamil on the Anti-tumour Action of Mitozantrone and Doxorubicin against Renal Carcinoma Cellsin vitro

1990 • 1 citations

Phase II trial of 1,2,4-triglycidylurazol in patients with metastasized renal cell carcinoma.

1987 • 1 citations

TCNU in advanced renal cancer

1989 • 1 citations

Phase II Clinical Evaluation of AZQ in Renal Cell Carcinoma

1986 • 1 citations