Fragile sites in human and Macaca fascicularis chromosomes are breakpoints in chromosome evolution.

Constitutive Fragile Sites and Cancer

1984 • 693 citations

The Origin of Man: A Chromosomal Pictorial Legacy

1982 • 665 citations

Expression of Fragile Sites Triggers Intrachromosomal Mammalian Gene Amplification and Sets Boundaries to Early Amplicons

1997 • 399 citations

Fragile sites are targets of diverse mutagens and carcinogens.

1987 • 264 citations

Genes encoding human caveolin‐1 and ‐2 are co‐localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers

1998 • 227 citations

Molecular characterization of a common fragile site ( FRA7H ) on human chromosome 7 by the cloning of a simian virus 40 integration site

1998 • 210 citations

Homologies in human and Macasa fuscata chromosomes revealed by in situ suppression hybridization with human chromosome specific DNA libraries

1992 • 179 citations

Heritable fragile sites on human chromosomes II. Distribution, phenotypic effects, and cytogenetics.

1979 • 172 citations

Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2

1995 • 168 citations

Cancer-specific chromosome alterations in the constitutive fragile region FRA3 B

1999 • 124 citations

Cytogenetic effects of radiotherapy breakpoint distribution in induced chromosome aberrations

1989 • 107 citations

Fragile sites, chromosome evolution, and human neoplasia

1987 • 80 citations

Evolutionary conservation of fragile sites induced by 5-azacytidine and 5-azadeoxycytidine in man, gorilla, and chimpanzee

1985 • 67 citations

Common fragile sites in man and three closely related primate species

1990 • 56 citations

Introduction

1991 • 56 citations

A comparative mapping study of fragile sites in the human and murine genomes

1987 • 53 citations

Site-specific chromosomal rearrangements induced in human diploid cells by x-irradiation

1986 • 53 citations

Fragile Sites—Cytogenetic Similarity with Molecular Diversity

1999 • 42 citations

Chromosomal homologies between humans and Cebus apella (Primates) revealed by ZOO-FISH

2000 • 36 citations

How common are common fragile sites: variation of aphidicolin-induced chromosomal fragile sites in a population of the deer mouse ( Peromyscus maniculatus )

1997 • 26 citations

Identifying chromosomal fragile sites from individuals: a multinomial statistical model

1995 • 25 citations

Risk of chromosomal disease due to radiation tentative estimate from the study of radiation-induced translocations in human fibroblasts

1983 • 25 citations

Diagrammatic representation for chromosomal mutagenesis studiesII. Radiation-induced rearrangements in Macaca fascicularis

1984 • 21 citations

Chromosome evolution in the cercopithecidae and its relationship to human fragile sites and neoplasia

1990 • 16 citations

Diagrammatic representation for chromosomal mutagenesis studies III. Radiation-induced rearrangements in Pan troglodytes (chimpanzee)

1985 • 14 citations

Chromosome abnormalities in peripheral blood lymphocytes from Macaca fascicularis and Erythrocebus patas (Cercopithecidae, Catarrhini) after X-ray irradiation

1998 • 11 citations

Expression of common fragile sites in two Ceboidea species: Saimiri boliviensis and Alouatta caraya (Primates: Platyrrhini)

2000 • 10 citations