Nerve Growth Factor and Insulin: Evidence of Similarities in Structure, Function, and Mechanism of Action

Protein Purification by Affinity Chromatography

1970 • 2,809 citations

Radioimmunoassay for Cyclic Nucleotides

1972 • 2,057 citations

Nerve growth factor.

1968 • 2,025 citations

Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)

1968 • 976 citations

Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo

1951 • 947 citations

THE NERVE GROWTH FACTOR: PURIFICATION AS A 30,000-MOLECULAR-WEIGHT PROTEIN

1969 • 920 citations

Structure of Rhombohedral 2 Zinc Insulin Crystals

1969 • 484 citations

The nerve growth factor: its mode of action on sensory and sympathetic nerve cells.

1966 • 456 citations

Insulin-Receptor Interactions in Adipose Tissue Cells: Direct Measurement and Properties

1971 • 443 citations

Essential role of the nerve growth factor in the survival and maintenance of dissociated sensory and sympathetic embryonic nerve cells in vitro

1963 • 417 citations

“Pleiotypic Response”

1971 • 415 citations

Nerve Growth Factor from Mouse Submaxillary Gland: Amino Acid Sequence

1971 • 401 citations

Isolation of the Insulin Receptor of Liver and Fat-Cell Membranes

1972 • 397 citations

INTERACTION OF INSULIN WITH THE CELL MEMBRANE: THE PRIMARY ACTION OF INSULIN

1969 • 381 citations

Species variation in the amino acid sequence of insulin

1966 • 322 citations

Selective Induction by Nerve Growth Factor of Tyrosine Hydroxylase and Dopamine-β-Hydroxylase in the Rat Superior Cervical Ganglia

1971 • 308 citations

Atomic Positions in Rhombohedral 2-Zinc Insulin Crystals

1971 • 304 citations

Nerve Growth Factor and Insulin

1972 • 283 citations

Modulation of Adenylate Cyclase Activity in Liver and Fat Cell Membranes by Insulin

1972 • 243 citations

Properties of the Insulin Receptor of Isolated Fat Cell Membranes

1971 • 227 citations

Affinity Chromatography and Purification of the Insulin Receptor of Liver Cell Membranes

1972 • 219 citations

X-Ray Diffraction Studies of Enzymes

1970 • 194 citations

Nerve Growth Factor: Stimulation of Regenerative Growth of Central Noradrenergic Neurons

1972 • 153 citations

Subunit structure and amino acid composition of mouse submaxillary gland nerve growth factor

1971 • 134 citations

Studies on Human Proinsulin

1971 • 129 citations

Amino acid sequences of mouse 2.5S nerve growth factor. II. Isolation and characterization of the thermolytic and peptic peptides and the complete covalent structure

1973 • 124 citations

EFFECTS OF A NERVE‐GROWTH FACTOR, EMBRYO AGE AND METABOLIC INHIBITORS ON GROWTH OF FIBRES AND ON SYNTHESIS OF RIBONUCLEIC ACID AND PROTEIN IN EMBRYONIC SYMPATHETIC GANGLIA¹

1971 • 111 citations

Physical studies on proinsulin — Association behavior and conformation in solution

1968 • 106 citations

Interaction of Nerve Growth Factor with Surface Membranes: Biological Competence of Insolubilized Nerve Growth Factor

1973 • 102 citations

Topography of mouse 2.5S nerve growth factor. Reactivity of tyrosine and tryptophan

1973 • 101 citations

Nerve Growth Factor: Enhanced Recovery of Feeding after Hypothalamic Damage

1973 • 93 citations

Neurite development in vitro. I. The effects of adenosine 3′5′‐cyclic monophosphate (cyclic AMP)

1972 • 73 citations

Effect of Insulin on the Growth Pattern and Adenylate Cyclase Activity of BHK Fibroblasts

1973 • 72 citations

Adenylate Cyclase and Insulin Action

1972 • 72 citations

Studies on the Mechanism of Action of Nerve Growth Factor

1972 • 71 citations

Posttranscriptional Control of Tyrosine Aminotransferase Synthesis by Insulin

1970 • 64 citations

Mechanism of Action of Nerve Growth Factor and Cyclic AMP on Neurite Outgrowth in Embryonic Chick Sensory Ganglia: Demonstration of Independent Pathways of Stimulation

1973 • 60 citations

Interaction of zing with proinsulin

1970 • 59 citations

Amino acid sequences of mouse 2.5S nerve growth factor. I. Isolation and characterization of the soluble tryptic and chymotryptic peptides

1973 • 56 citations

X-Ray Studies of Protein Mechanisms

1972 • 42 citations

Structure and Function of Proteins

1971 • 42 citations

Use of N-methylnicotinamide chloride as a conformational probe in proteins. Identification of the binding sites in chicken egg-white lysozyme and a comparison with bovine α-lactalbumin

1970 • 38 citations

Preparation and properties of 3-nitrotyrosine insulins

1970 • 29 citations

Physical studies on proinsulin. Comparison of the titration behavior of the tyrosine residues in insulin and proinsulin

1972 • 28 citations

THE USE OF N -METHYLNICOTINAMINDE CHLORIDE AS A CONFORMATIONAL PROBE FOR CHICKEN EGG-WHITE LYSOZYME

1969 • 18 citations

Rat Proinsulins and C-Peptides. Isolation and Amino-Acid Compositions

1972 • 18 citations