High serum levels of soluble interleukin 2 receptor in patients with B chronic lymphocytic leukemia

Clinical staging of chronic lymphocytic leukemia

1975 • 2,706 citations

Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.

1985 • 1,143 citations

Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.

1984 • 742 citations

Novel Interleukin-2 Receptor Subunit Detected by Cross-Linking Under High-Affinity Conditions

1986 • 585 citations

Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells

1984 • 375 citations

Activated B cells express receptors for, and proliferate in response to, pure interleukin 2.

1984 • 361 citations

The released interleukin 2 receptor binds interleukin 2 efficiently.

1986 • 348 citations

Subsequent Neoplasia in Chronic Lymphocytic Leukemia

1975 • 181 citations

Subsequent Cancer in Patients With Chronic Lymphocytic Leukemia—A Possible Immunologic Mechanism

1978 • 155 citations

T-cell subpopulations in chronic lymphocytic leukemia: abnormalities in distribtuion and in in vitro receptor maturation

1979 • 134 citations

Soluble interleukin-2 receptors in the serum of patients with Hodgkin's disease

1987 • 116 citations

Clinical staging and immunological findings in chronic lymphocytic leukemia

1979 • 93 citations

Immunohistologic study of bone marrow involvement in B-chronic lymphocytic leukemia

1983 • 90 citations

Common and pre-B acute lymphoblastic leukemia cells express interleukin 2 receptors, and interleukin 2 stimulates in vitro colony formation

1985 • 80 citations

Abnormal expansions of polyclonal large to small size granular lymphocytes: reactive or neoplastic process?

1984 • 67 citations

Increased Incidence of Neoplasia in Association with Chronic Lymphocytic Leukaemia

1969 • 62 citations

Interleukin 2 (IL 2) and interferon-gamma production by T lymphocytes from patients with B-chronic lymphocytic leukemia: evidence that normally released IL 2 is absorbed by the neoplastic B cell population

1985 • 52 citations

Interleukin 2 receptors are released by cells in vitro and in viva. I. Detection of soluble IL 2 receptors in cell culture supernatants and in the serum of mice by an immunoradiometric assay

1986 • 52 citations

T-lymphocyte subpopulations in chronic lymphocytic leukemia: A quantitative and functional study

1981 • 47 citations

Lymphokine induction of NK-like cytotoxicity in T cells from B-CLL

1986 • 46 citations

T lymphocytes in B-cell chronic lymphocytic leukemia: Characterization by monoclonal antibodies and correlation with Fc receptors

1983 • 44 citations

Detection of a Soluble form of the Receptor for Interleukin 2 in the Serum of Patients with Hairy Cell Leukaemia

1986 • 40 citations

Defective T cell responsiveness in chronic lymphocytic leukemia: analysis of activation events

1986 • 37 citations

Human T lymphocytes

1986 • 20 citations

Abnormal T-cell functions in B-cell chronic lymphocytic leukemia do not imply T-lymphocyte involvement in the leukemic process: Report of a case with demonstrated ?polyclonality? of T lymphocytes

1983 • 15 citations

The serum immunoglobulins in lymphoproliferative malignancies

1978 • 8 citations