The identification of the major excreted protein (MEP) from a transformed mouse fibroblast cell line as a catalytically active precursor form of cathepsin L

Statistical estimations in enzyme kinetics

1961 • 3,586 citations

[41] Cathepsin B, cathepsin H, and cathepsin L

1981 • 1,678 citations

L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L

1982 • 1,024 citations

Cysteine proteinases and metastasis

1984 • 211 citations

Human liver cathepsin L

1985 • 191 citations

Transformation-dependent secretion of a low molecular weight protein by murine fibroblasts.

1978 • 149 citations

Phosphorylation, glycosylation, and proteolytic activity of the 52-kD estrogen-induced protein secreted by MCF7 cells.

1987 • 147 citations

The major excreted protein of transformed fibroblasts is an activable acid-protease.

1986 • 147 citations

Cloning and characterization of a mouse cysteine proteinase.

1986 • 137 citations

Calpain inhibition by peptide epoxides

1985 • 106 citations

The purification and properties of cathepsin L from rabbit liver

1984 • 105 citations

Comparison of live human neutrophil and alveolar macrophage elastolytic activity in vitro. Relative resistance of macrophage elastolytic activity to serum and alveolar proteinase inhibitors.

1984 • 96 citations

Processing and lysosomal localization of a glycoprotein whose secretion is transformation stimulated.

1985 • 89 citations

Interrelationship of active and latent secreted human cathepsin B precursors

1986 • 82 citations

Species variants of cathepsin L and their immunological identification

1986 • 69 citations

The major excreted protein (MEP) of transformed mouse cells and cathepsin L have similar protease specificity

1986 • 66 citations

Close relationship of the major excreted protein of transformed murine fibroblasts to thiol-dependent cathepsins.

1986 • 58 citations

Collagen degradation in an experimental inflammatory lesion: studies on the role of the macrophage.

1981 • 57 citations

The N-terminal amino acid sequences of the heavy and light chains of human cathepsin L Relationship to a cDNA clone for a major cysteine proteinase from a mouse macrophage cell line

1986 • 42 citations

Biochemical and immunological studies of lysosomal and related proteinases in health and disease

1981 • 37 citations

Inactivation of cathepsin B1 by diazomethyl ketones

1977 • 34 citations

Increased cathepsin B-like activity in alveolar macrophages and bronchoalveolar lavage fluid from smokers.

1986 • 31 citations

Cathepsin B-like cysteine proteinase activity in sputum and immunohistologic identification of cathepsin B in alveolar macrophages.

1983 • 29 citations

The fluorescence and bright field microscopic demonstration of cathepsin B in human fibroblasts

1979 • 24 citations