Induced neurogenesis by endogeneous progenitor cells in the adult mammalian brain

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

Mammalian Neural Stem Cells

2000 • 4,689 citations

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

1996 • 3,012 citations

Long-Distance Neuronal Migration in the Adult Mammalian Brain

1994 • 2,291 citations

Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone

1993 • 1,799 citations

The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4

1996 • 1,604 citations

A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes

1992 • 1,514 citations

BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra

1991 • 1,487 citations

Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia.

1993 • 1,319 citations

Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

2001 • 1,293 citations

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

1990 • 1,238 citations

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

1997 • 1,206 citations

Induction of neurogenesis in the neocortex of adult mice

2000 • 1,201 citations

Interference by Huntingtin and Atrophin-1 with CBP-Mediated Transcription Leading to Cellular Toxicity

2001 • 1,085 citations

Noggin Antagonizes BMP Signaling to Create a Niche for Adult Neurogenesis

2000 • 1,064 citations

Neuronal production, migration, and differentiation in a vocal control nucleus of the adult female canary brain.

1983 • 983 citations

Infusion of Brain-Derived Neurotrophic Factor into the Lateral Ventricle of the Adult Rat Leads to New Neurons in the Parenchyma of the Striatum, Septum, Thalamus, and Hypothalamus

2001 • 925 citations

Neurotrophic factors: from molecule to man

1994 • 800 citations

Alternative Neural Crest Cell Fates Are Instructively Promoted by TGFβ Superfamily Members

1996 • 785 citations

In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain

1996 • 757 citations

Bone Morphogenetic Proteins Promote Astroglial Lineage Commitment by Mammalian Subventricular Zone Progenitor Cells

1996 • 681 citations

Understanding cell death in parkinson's disease

1998 • 678 citations

Progenitor cells of the adult mouse subventricular zone proliferate, migrate and differentiate into oligodendrocytes after demyelination

1999 • 536 citations

Is there a neural stem cell in the mammalian forebrain?

1996 • 535 citations

Adenoviral Brain-Derived Neurotrophic Factor Induces Both Neostriatal and Olfactory Neuronal Recruitment from Endogenous Progenitor Cells in the Adult Forebrain

2001 • 531 citations

Intraventricular Administration of BDNF Increases the Number of Newly Generated Neurons in the Adult Olfactory Bulb

1998 • 528 citations

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells

1986 • 519 citations

Alzheimer's disease

1998 • 517 citations

Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain

1995 • 470 citations

The generation, migration, and differentiation of olfactory neurons in the adult primate brain

2001 • 416 citations

In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain

2000 • 412 citations

Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors

1993 • 387 citations

Endothelial Trophic Support of Neuronal Production and Recruitment from the Adult Mammalian Subependyma

1999 • 384 citations

Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor

1985 • 384 citations

Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture

1988 • 343 citations

BDNF enhances the differentiation but not the survival of CNS stem cell- derived neuronal precursors

1995 • 340 citations

Brain basic fibroblast growth factor stimulates the proliferation of rat neuronal precursor cells in vitro

1987 • 336 citations

Proliferation “hot spots” in adult avian ventricular zone reveal radial cell division

1990 • 322 citations

Brain-derived neurotrophic factor promotes the survival of neurons arising from the adult rat forebrain subependymal zone.

1995 • 309 citations

EGF and TGF-α stimulate retinal neuroepithelial cell proliferation in vitro

1991 • 286 citations

The Division of Neuronal Progenitor Cells during Migration in the Neonatal Mammalian Forebrain

1995 • 269 citations

The NeurotroDhins BDNF, NT-3 and NT-4/5 Promote Survival and Morphological and Biochemical Differentiation of Striatal NeuronsIn Vitro

1995 • 262 citations

Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection

1993 • 254 citations

The response of chick sensory neurons to brain-derived neurotrophic factor

1986 • 251 citations

Identification, Isolation, and Promoter-Defined Separation of Mitotic Oligodendrocyte Progenitor Cells from the Adult Human Subcortical White Matter

1999 • 250 citations

Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytes

1988 • 249 citations

Insulin-Like Growth Factor-I Is a Differentiation Factor for Postmitotic CNS Stem Cell-Derived Neuronal Precursors: Distinct Actions from Those of Brain-Derived Neurotrophic Factor

1998 • 245 citations

Development of lentiviral vectors for gene therapy for human diseases

2000 • 241 citations

Changes in neurotrophin responsiveness during the development of cerebellar granule neurons

1992 • 240 citations

Patterns of cell loss in Huntington's disease

1987 • 226 citations

Distribution of Intracerebral Ventricularly Administered Neurotrophins in Rat Brain and Its Correlation with Trk Receptor Expression

1994 • 213 citations

Developmental Changes in Progenitor Cell Responsiveness to Bone Morphogenetic Proteins Differentially Modulate Progressive CNS Lineage Fate

2000 • 207 citations

Quantitative immunocytochemistry of DARPP-32-expressing neurons in the rat caudatoputamen

1998 • 197 citations

Neuronal stem cells in the brain of adult vertebrates

1995 • 193 citations

The Neurotrophins BDNF, NT‐3 and NT‐4/5, But Not NGF, Up‐regulate the Cholinergic Phenotype of Developing Motor Neurons

1993 • 192 citations

Chapter 1 The subventricular zone: source of neuronal precursors for brain repair

2000 • 187 citations

Adult neurogenesis: from canaries to the clinic.

1998 • 171 citations

The selective vulnerability of striatopallidal neurons

1999 • 168 citations

Expression of the Striatal DARPP-32/ARPP-21 Phenotype in GABAergic Neurons Requires NeurotrophinsIn VivoandIn Vitro

1999 • 148 citations

Adult neurogenesis: From canaries to the clinic

1998 • 139 citations

In vitro survival and differentiation of neurons derived from epidermal growth factor-responsive postnatal hippocampal stem cells: Inducing effects of brain-derived neurotrophic factor

1998 • 137 citations

Strategies utilized by migrating neurons of the postnatal vertebrate forebrain

1998 • 132 citations

Neurotrophins Stimulate Chemotaxis of Embryonic Cortical Neurons

1997 • 92 citations

Cortical Interneurons Upregulate Neurotrophinsin Vivoin Response to Targeted Apoptotic Degeneration of Neighboring Pyramidal Neurons

1998 • 88 citations

Trophic and protective actions of brain-derived neurotrophic factor on striatal DARPP-32-containing neurons in vitro

1995 • 79 citations

Brain-derived neurotrophic factor regulates maturation of the DARPP-32 phenotype in striatal medium spiny neurons: studies in vivo and in vitro

1997 • 79 citations

Intra-CSF administered recombinant adenovirus causes an immune response-mediated toxicity

2000 • 74 citations

Isolation, Characterization and Utilization of CNS Stem Cells

1997 • 60 citations

Intraparenchymal NGF Infusions Rescue Degenerating Cholinergic Neurons

2000 • 58 citations

Adenovirus-mediated gene delivery into neuronal precursors of the adult mouse brain.

1996 • 55 citations

In vitro neurogenesis by neuronal precursor cells derived from the adult songbird brain

1992 • 47 citations

Stem Cells and CNS Development

2001 • 37 citations

Comparative Strategies of Subependymal Neurogenesis in the Adult Forebrain

1997 • 25 citations

Neural Progenitor Cells of the Adult Human Brain

2006 • 5 citations