Neuroendocrine—Thymus Interactions During Development and Aging

Release of Multiple Hormones by a Direct Action of Interleukin-1 on Pituitary Cells

1987 • 670 citations

Effect of castration and sex hormone treatment on survival, anti-nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice.

1978 • 637 citations

Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells

1985 • 613 citations

ASSOCIATION BETWEEN BIOLOGICAL PROPERTIES OF HUMAN IMMUNODEFICIENCY VIRUS VARIANTS AND RISK FOR AIDS AND AIDS MORTALITY

1989 • 581 citations

Thymus and Reproduction: Sex-Linked Dysgenesia of the Gonad after Neonatal Thymectomy in Mice

1969 • 554 citations

Progress in Allergy.

1949 • 499 citations

The Involution of the Ageing Human Thymic Epithelium is Independent of Puberty

1985 • 434 citations

Changes in Blood Hormone Levels during the Immune Response

1975 • 342 citations

Neuroendocrine rhythms and sleep in aging men

1991 • 335 citations

Contribution of zinc and other metals to the biological activity of the serum thymic factor.

1982 • 315 citations

ISOLATION, BIOCHEMICAL CHARACTERISTICS, AND BIOLOGICAL ACTIVITY OF A CIRCULATING THYMIC HORMONE IN THE MOUSE AND IN THE HUMAN

1975 • 288 citations

Prolactin as a modulator of lymphocyte responsiveness provides a possible mechanism of action for cyclosporine.

1986 • 247 citations

Immune-neuroendocrine circuits: integrative role of cytokines.

1992 • 207 citations

Approach to the study of the role of sex hormones in autoimmunity

1979 • 201 citations

The Neuroendocrine Thymus: Coexistence of Oxytocin and Neurophysin in the Human Thymus

1986 • 183 citations

Stable Isotope Studies of Zinc Absorption and Retention in Young and Elderly Men

1986 • 166 citations

THYMIC HORMONE DEFICIENCY IN NORMAL AGEING AND DOWN'S SYNDROME: IS THERE A PRIMARY FAILURE OF THE THYMUS?

1984 • 157 citations

On the Immunological Theory of Aging

2014 • 154 citations

Thyroid Function Modulates Thymic Endocrine Activity*

1986 • 150 citations

Lymphocytes, Hormones and Ageing

1972 • 149 citations

3 Clinical, endocrinological and biochemical effects of zinc deficiency

1985 • 149 citations

The Pineal Control of Aging

1991 • 146 citations

Thymus involvement in female sexual maturation

1974 • 144 citations

Enkephalins and endorphins as modifiers of the immune system: present and future.

1985 • 132 citations

Regeneration of the thymus in old male rats treated with a stable analogue of LHRH

1987 • 123 citations

AN IMMUNOLOGICAL APPROACH TO AGEING

1970 • 123 citations

Cellular interactions in the immune response

1972 • 122 citations

Immunodepression in thyroid-deprived animals.

1973 • 121 citations

Hormones and the immunological capacity. IV. Restorative effects of developmental hormones or of lymphocytes on the immunodeficiency syndrome of the dwarf mouse.

1971 • 120 citations

Role of growth hormone in regulating T‐Dependent immune events in aged, nude, and transgenic rodents

1987 • 117 citations

Growth hormone treatment stimulates thymulin production in aged dogs.

1987 • 116 citations

Hormones and the immunological capacity. 3. The immunodeficiency disease of the hypopituitary Snell-Bagg dwarf mouse.

1971 • 115 citations

Endocrine control of thymic serum factor production in young-adult and old mice

1985 • 112 citations

Neuroendocrinology of Aging

1983 • 102 citations

Age involution in the normal human adult thymus.

1975 • 101 citations

Thymic hormone‐containing cells. VI. Immunohistologic evidence for the simultaneous presence of thymulin, thymopoietin and thymosin α₁ in normal and pathological human thymuses

1984 • 94 citations

The Neurohormonal Thymic Microenvironment: Immunocytochemical Evidence that Thymic Nurse Cells Are Neuroendocrine Cells

1988 • 93 citations

Alterations of Adrenal Cortex and Thyroid in Mice with Congenital Absence of the Thymus

1972 • 92 citations

Role for Protein Phosphorylation in Meiosis and in the Early Cleavage Phase of Amphibian Embryonic Development

1972 • 90 citations

The Thymus: Experimental and Clinical Studies.

1967 • 89 citations

Effects of hormones on development and function of lymphoid tissues. Synergistic action of thyroxin and somatotropic hormone in pituitary dwarf mice.

1969 • 89 citations

Why the neuroendocrine system is important in aging processes

1987 • 87 citations

Vasopressin replacement of interleukin 2 requirement in gamma interferon production: lymphokine activity of a neuroendocrine hormone.

1982 • 81 citations

Interdependence of thymic and neuroendocrine functions in ontogeny.

1976 • 72 citations

Endocrine interaction of the thymus with the hypohysis, adrenals and testes: effects of two thymic extracts.

1979 • 62 citations

Zinc Affects the Metabolism of Thyroid Hormones in Children with Down's Syndrome: Normalization of Thyroid Stimulating Hormone and of Reversal Triiodothyronine Plasmic Levels by Dietary Zinc Supplementation

1992 • 62 citations

Neuroendocrine‐Thymus Interactions: Perspectives for Intervention in Aginga

1988 • 62 citations

Generation of cytotoxic cells from murine bone marrow by human recombinant IL 2.

1986 • 60 citations

Respective Influence of Extrinsic and Intrinsic Factors on the Age-Related Decrease of Thymic Secretion

1979 • 58 citations

Long-Term Effects of Neonatal Estrogen Treatment on Mitogen Responsiveness of Mouse Spleen Lymphocytes<xref ref-type="fn" rid="FN2">2</xref>

1979 • 55 citations

Influence of Growth Hormone on Thymic Endocrine Activity in Humans

1990 • 55 citations

Book Review: The Thymus: Experimental and Clinical Studies

1967 • 54 citations

Thymosin Fraction 5 Stimulates Prolactin and Growth Hormone Release from Anterior Pituitary Cellsin Vitro*

1987 • 53 citations

Thymus-dependent recersibility of physiological and isoproterenol evoked age-related parameters in athymic (nude) and old normal mice

1978 • 53 citations

Thymosins, Lymphokines, and the Immunology of Aging

1985 • 53 citations

Recovery of age-dependent immunological deterioration in Balb/c mice by short-term treatment with L-thyroxine

1982 • 52 citations

Improvement in clinical condition and thymus morphologic features associated with growth hormone treatment of immunodeficient dwarf dogs.

1984 • 51 citations

Developmental hormones and immunological maturation.

1970 • 50 citations

A Quantitative Histologic Comparison of the Thymus in 100 Healthy and Diseased Adults

1981 • 49 citations

Recovery of spleen cell natural killer activity by thyroid hormone treatment in old mice.

1991 • 49 citations

Hormones and the immune response.

1989 • 48 citations

Generation of natural killer cells from bone marrow precursors in vitro.

1986 • 47 citations

The influence of preoperative drug treatment on the extent of hyperplasia of the thymus in primary thyrotoxicosis.

1975 • 47 citations

Zinc-Dependent Low Thymic Hormone Level in Type I Diabetes

1989 • 46 citations

Effect of Oral Zinc Administration on Prolactin and Thymulin Circulating Levels in Patients With Chronic Renal Failure*

1989 • 45 citations

TRIIODOTHYRONINE AND THYROXINE NUCLEAR RECEPTORS IN LYMPHOCYTES FROM NORMAL, HYPER- AND HYPOTHYROID SUBJECTS

1977 • 44 citations

Cellular Interactions in the Immune Response.

1972 • 42 citations

At the cutting edge biosynthesis and paracrine/cryptocrine actions of ‘self’ neurohypophysial-related peptides in the thymus

1991 • 39 citations

Thymic abnormalities and growth hormone deficiency in dogs.

1980 • 36 citations

Thymic regulation of brain cortex beta-adrenoceptors during development and aging

1985 • 36 citations

Psychoimmunologic and Endorphin Function in the Ageda

1988 • 36 citations

The Role of Zinc in Neuroendocrine‐Immune Interactions during Aging

1991 • 36 citations

Modulation of lymphoid cell sensitivity to interferon by thyroid hormones

1990 • 35 citations

Biomarkers of Aging in the Neuroendocrine‐Immune Domain

1992 • 35 citations

Neuroendocrine-thymus interactions. I. In vitro modulation of thymic factor secretion by thyroid hormones

1990 • 34 citations

Production of Neuroendocrine Peptide Hormones by the Immune System

1988 • 33 citations

Timing of appearance and disappearance of IFN and IL-2 induced natural immunity during ontogenetic development and aging

1989 • 32 citations

Electron-microscopic morphometric analysis of mouse liver. II. Effect of ageing and thymus transplantation in old animals

1980 • 32 citations

Die normal-morphologische Thymusforschung im letzten Vierteljahrhundert : analyse und Synthese, nebst einigen Worten zu der Funktionsfrage

1936 • 32 citations

Recovery of age-related decline of thymic endocrine activity and PHA response by lysin-arginine combination

1986 • 27 citations

Structural and Functional Alterations of the Aging Human Thymus

1982 • 26 citations

Bilateral Communication Between the Endocrine and Immune Systems

1994 • 26 citations

Models and mechanisms of neuroendocrine-immune interactions during ontogeny

1991 • 22 citations

DEFICIENCY IN THE THYMUS-DEPENDENT IMMUNITY IN “LETHARGIC” MUTANT MICE1

1977 • 21 citations

Thymulin Deficiency and Low 3,5,3′-Triiodothyronine Syndrome in Infants with Low Birth Weight Syndromes^*

1987 • 21 citations

Zinc-dependent low thymic hormone level in type I diabetes

1989 • 16 citations

Recovery of low thymic hormone levels in cancer patients by lysine-arginine combination

1990 • 16 citations

The Pineal Gland: An Important Link to the Environment

1986 • 16 citations

Growth hormone‐induced t cell differentiation

1973 • 15 citations

Role of Pituitary-Thyroid Axis on Basal and Lymphokine-Induced NK Cell Activity in Aging

1990 • 15 citations

The Effects of Cortisone on Acetylcholinesterase (AChE) in the Neonatal and Aged Thymusa

1988 • 15 citations

Aging of the Reproductive‐Neuroimmune Axis

1991 • 15 citations

Ontogenetic and phylogenetic aspects of neuro-endocrine-immune network

1981 • 13 citations

Neuroimmunoendocrinology

1988 • 11 citations

Thymulin and Zinc Circulating Levels in Patients with GH and PRL Secreting Pituitary Adenomas

1990 • 11 citations

Thymus-Neuroendocrine Network

1983 • 11 citations

Electron-microscopic morphometric analysis of mouse liver. I. Experimental studies on the morphogenetic significance of the thymus in nude and normal mice

1980 • 9 citations

An Immunological Approach to Aging^a

1992 • 5 citations

Growth Hormone Influence on Thymic Endocrine Activity in Humans

1990 • 4 citations