Systemic Embolism in Endocarditis: Incidence, Risk Factors, Clinical Significance, and Treatment Strategies

ACC/AHA guidelines for the management of patients with valvular heart disease

1998 • 1,161 citations

Echocardiography in infective endocarditis: Reassessment of prognostic implications of vegetation size determined by the transthoracic and the transesophageal approach

1989 • 657 citations

Risk of Embolism and Death in Infective Endocarditis: Prognostic Value of Echocardiography

2005 • 654 citations

Prosthetic valve endocarditis.

1984 • 512 citations

Fungal Endocarditis: Evidence in the World Literature, 1965-1995

2001 • 485 citations

Risk of embolization after institution of antibiotic therapy for infective endocarditis

2002 • 440 citations

Echocardiography predicts embolic events in infective endocarditis

2001 • 439 citations

NEUROLOGIC COMPLICATIONS OF BACTERIAL ENDOCARDITIS

1978 • 424 citations

Emboli in Infective Endocarditis: The Prognostic Value of Echocardiography

1991 • 407 citations

Neurologic Manifestations of Infective Endocarditis

2000 • 402 citations

Antithrombotic Therapy in Valvular Heart Disease—Native and Prosthetic

2004 • 383 citations

Improved diagnostic value of echocardiography in patients with infective endocarditis by transoesophageal approach. A prospective study

1988 • 380 citations

Echocardiographic assessment of patients with infectious endocarditis: Prediction of risk for complications

1991 • 326 citations

Risk Factors for

2002 • 307 citations

Surgical management of infective endocarditis associated with cerebral complications

1995 • 300 citations

Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications.

1980 • 272 citations

Improved diagnostic value of echocardiography in patients with infective endocarditis by transoesophageal approach. A prospective study

1988 • 267 citations

Preceding infection as an important risk factor for ischaemic brain infarction in young and middle aged patients

1988 • 260 citations

A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis

2003 • 226 citations

The risk of stroke and death in patients with aortic and mitral valve endocarditis

2001 • 217 citations

Staphylococcus aureusProtein A Recognizes Platelet gC1qR/p33: a Novel Mechanism for Staphylococcal Interactions with Platelets

2000 • 192 citations

Infective endocarditis, 1983–1988: Echocardiographic findings and factors influencing morbidity and mortality

1990 • 192 citations

Valve replacement in patients with endocarditis and acute neurologic deficit

1996 • 187 citations

Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis

1996 • 159 citations

Acetylsalicylic Acid Reduces Vegetation Bacterial Density, Hematogenous Bacterial Dissemination, and Frequency of Embolic Events in Experimental Staphylococcus aureus Endocarditis Through Antiplatelet and Antibacterial Effects

1999 • 156 citations

Precipitants of Brain Infarction

1996 • 144 citations

The ability of vegetation size on echocardiography to predict clinical complications: A meta-analysis

1997 • 140 citations

Relation between the presence of echocardiographic vegetations and the complication rate in infective endocarditis

1986 • 134 citations

Anticoagulant therapy and central nervous system complications in patients with prosthetic valve endocarditis.

1978 • 133 citations

Role of transthoracic and transesophageal echocardiography in predicting embolic events in patients with active infective endocarditis involving native cardiac valves

1997 • 133 citations

Impact of Prior Antiplatelet Therapy on Risk of Embolism in Infective Endocarditis

2007 • 132 citations

Endocarditis in the elderly: clinical, echocardiographic, and prognostic features

2003 • 127 citations

Risk factors for “major” embolic events in hospitalized patients with infective endocarditis

2003 • 124 citations

Prognostic significance of vegetations detected by two-dimensional echocardiography in infective endocarditis

1986 • 119 citations

Fungal endocarditis

1995 • 111 citations

Isolated pulmonic valve endocarditis in healthy hearts: a case report and review of the literature.

2000 • 110 citations

Comparison of M-mode and cross-sectional echocardiography in infective endocarditis.

1979 • 109 citations

The presence of infection-related antiphospholipid antibodies in infective endocarditis determines a major risk factor for embolic events

1999 • 101 citations

Surgical treatment of endocarditis

1997 • 99 citations

Expression of endothelial cell adhesion molecules on heart valves: up-regulation in degeneration as well as acute endocarditis

2000 • 98 citations

Risk factors for systemic emboli in infective endocarditis

2004 • 93 citations

Prosthetic valve endocarditis 1976-1987. Antibiotics, anticoagulation, and stroke.

1990 • 93 citations

Role of the Vegetation in Experimental Streptococcus viridans Endocarditis

1974 • 89 citations

Effect of Long-Term Aspirin Use on Embolic Events in Infective Endocarditis

2007 • 87 citations

Quantification of regional myocardial perfusion by PET: Rationale and first clinical results

1995 • 87 citations

Cardiac receptor activation and arrhythmogenesis

1993 • 84 citations

Vegetations in infective endocarditis. Clinical relevance and diagnosis by cross sectional echocardiography.

1985 • 81 citations

Fungal endocarditis

2004 • 81 citations

Influence of aspirin on development and treatment of experimental Staphylococcus aureus endocarditis

1995 • 67 citations

Rate of Cerebral Embolic Events in Relation to Antibiotic and Anticoagulant Therapy in Patients with Bacterial Endocarditis

1990 • 61 citations

Clinical Implications of Large Vegetations in Infectious Endocarditis

1983 • 58 citations

Aspirin to prevent growth of vegetations and cerebral emboli in infective endocarditis

1992 • 58 citations

Beneficial effect of combination antiplatelet therapy on the development of experimental Staphylococcus aureus endocarditis

1999 • 53 citations

The Effect of Anticoagulants on the Penicillin Therapy and the Pathologic Lesion of Subacute Bacterial Endocarditis

1946 • 46 citations

[Neurologic complications of bacterial endocarditis].

1971 • 44 citations

Effect of antibiotic treatment on vegetation size and complication rate in infective endocarditis

1997 • 41 citations

Infective Endocarditis Successfully Treated in Extremely Low Birth Weight Infants With Recombinant Tissue Plasminogen Activator

2002 • 41 citations

Coagulation in Sepsis

2004 • 35 citations

Effect of warfarin on the induction and course of experimental Staphylococcus epidermidis endocarditis

1977 • 34 citations

Fatal intracerebral hemorrhage following thrombolytic therapy of embolic myocardial infarction in unsuspected infective endocarditis

1994 • 34 citations

Adhesion molecules (E-selectin, intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1)) in sera from patients withStaphylococcus aureusbacteraemia with or without endocarditis

1999 • 33 citations

Increased blood coagulation and platelet activation in patients with infective endocarditis and embolic events

2004 • 33 citations

Acute coronary embolism complicating aortic valve endocarditis treated with streptokinase and aspirin. A case report.

1994 • 31 citations

Effect of warfarin on the induction and course of experimental endocarditis

1976 • 30 citations

Successful treatment of infective endocarditis with recombinant tissue plasminogen activator

2003 • 30 citations

Increased levels of soluble adhesion molecules, E-selectin and P-selectin, in patients with infective endocarditis and embolic events

2001 • 29 citations

Influence of adjunctive ticlopidine on the treatment of experimental Staphylococcus aureus endocarditis

1998 • 26 citations

Infective Endocarditis in the Transesophageal Echocardiographic Era

1993 • 19 citations

Fibrinolytic therapy in bacterial endocarditis: Experimental studies in dogs

1986 • 14 citations

Successful treatment of a staphylococcal endocarditis vegetation with tissue plasminogen activator

1998 • 14 citations

Effects of tissue-type plasminogen activator (t-PA) on Streptococcus sanguis—infected endocardial vegetations in vitro

1988 • 11 citations

Effect of sulphinpyrazone on the development of experimental endocardial vegetations

1982 • 8 citations

Clinical implications of large vegetations in infectious endocarditis

1983 • 8 citations

Effects of tissue-type plasminogen activator on Staphylococcus epidermidis—infected plasma clots as a model of infected endocardial vegetations

1987 • 7 citations