Enzymatic Formation of Leukotrienes

Leukotriene C: a slow-reacting substance from murine mastocytoma cells.

1979 • 992 citations

Glutathione: Metabolism and function

1978 • 971 citations

Arachidonic acid metabolism in polymorphonuclear leukocytes

1979 • 812 citations

Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid.

1979 • 652 citations

Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases

1976 • 638 citations

Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds.

1979 • 556 citations

Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids.

1979 • 465 citations

Structure of slow-reacting substance of anaphylaxis from guinea-pig lung

1980 • 426 citations

THE LIBERATION OF A SLOW‐REACTING SMOOTH MUSCLE‐STIMULATING SUBSTANCE IN ANAPHYLAXIS

1940 • 416 citations

Liberation of histamine and formation of lysocithin‐like substances by cobra venom

1938 • 372 citations

Structure of leukotriene C identification of the amino acid part

1979 • 304 citations

Identification of the C(6)-S-conjugate of leukotriene a with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A). Importance of the 11-cis-geometry for biological activity

1980 • 267 citations

Slow Reacting Substance of Anaphylaxis

1969 • 230 citations

Serine-borate complex as a transition-state inhibitor of gamma-glutamyl transpeptidase.

1978 • 216 citations

Arachidonate 5-lipoxygenase of guinea pig peritoneal polymorphonuclear leukocytes. Activation by adenosine 5'-triphosphate.

1983 • 215 citations

Precursor role of arachidonic acid in release of slow reacting substance from rat basophilic leukemia cells.

1977 • 183 citations

Calcium stimulation of a novel lipoxygenase

1980 • 179 citations

Inhibition of leukotriene C and leukotriene D biosynthesis.

1980 • 171 citations

The physicochemical characteristics and purification of slow-reacting substance of anaphylaxis.

1973 • 167 citations

Leukotriene a: Stereochemistry and enzymatic conversion to leukotriene B

1980 • 162 citations

Characterization of Rat‐Liver Microsomal Glutathione S‐Transferase Activity

1980 • 155 citations

The Physicochemical Characteristics and Purification of Slow-Reacting Substance of Anaphylaxis

1973 • 146 citations

Enzymatic assembly of slow reacting substance

1980 • 122 citations

Solubilization and characterization of the leukotriene C4 synthetase of rat basophil leukemia cells: A novel, participate glutathione S-transferase

1984 • 121 citations

On the structure of slow reacting substance of anaphylaxis: Evidence of biosynthesis from arachidonic acid

1977 • 111 citations

Slow‐reacting substance of anaphylaxis Purification and characterisation

1978 • 107 citations

Leukotriene C5: a slow reacting substance derived from eicosapentaenoic acid.

1980 • 104 citations

Teteraene and pentaene leukotrienes: Selective production from murine mastocytomo cells after dietary manipulation

1981 • 102 citations

Leukotriene A4: preparation and enzymatic conversion in a cell-free system to leukotriene B4.

1982 • 87 citations

Sequential conversion of the glutathionyl side chain of slow reacting substance (SRS) to cysteinyl-glycine and cysteine in rat basophilic leukemia cells stimulated with A-23187

1980 • 82 citations

Leukotriene A4: Enzymatic conversion to leukotriene C4

1980 • 80 citations

Fatty acid structural requirements for leukotriene biosynthesis

1980 • 78 citations

Conversion of 5,8,11-eicosatrienoic acid to leukotrienes C3 and D3.

1981 • 76 citations

In Vivo and in Vitro Production of a Slow Reacting Substance in the Rat Upon Treatment with Calcium Ionophores

1974 • 75 citations

Characterization of the two major species of slow reacting substance from rat basophilic leukemia cells as glutathionyl thioethers of eicosatetraenoic acids oxygenated at the 5 position. Evidence that peroxy groups are present and important for spasmogenic activity

1979 • 71 citations

Characterization of leukotriene A4 and B4 bioysnthesis

1983 • 70 citations

Release of Slow Reacting Substance (SRS) from Rat Basophilic Leukemia (RBL-1) Cells

1977 • 69 citations

Purification and Properties of the Slow Reacting Substance Formed in the Cat Paw Perfused with Compound 48/80¹

1971 • 67 citations

Calcium stimulation of the 5-lipoxygenase from RBL-1 cells

1982 • 61 citations

Detection of leukotriene A₄ as an intermediate in the biosynthesis of leukotrienes C₄ and D₄

1980 • 60 citations

On the mechanism of biosynthesis of leukotrienes and related compounds

1982 • 60 citations

Leukotriene C4 and D4 formation by particulate enzymes.

1982 • 59 citations

Arachidonic acid metabolism in rat basophilic leukemia (RBL-1) cells

1978 • 55 citations

Characterization of slow reacting substances (SRSs) of rat basophilic leukemia (RBL-1) cells: effect of cysteine on SRS profile.

1980 • 47 citations

Products derived from 5,8,11-eicosatrienoic acid by the 5-lipoxygenase-leukotriene pathway.

1983 • 46 citations

Specific inhibition and oxidative regulation of 5-lipoxygenase.

1983 • 42 citations

Conversion of dihomo-gamma-linolenic acid to an isomer of leukotriene C3, oxygenated at C-8.

1981 • 40 citations

Enzymatic inactivation of SRS-Cys-Gly (leukotriene D)

1981 • 38 citations

Characterization of slow reacting substance as a family of thiolipids derived from arachidonic acid

1979 • 37 citations

Fatty acids as sources of potential “magic bullets” for the modification of platelet and vascular function

1981 • 33 citations

Metabolic factors regulating the generation of prostaglandins E1 and E2 by isolated rat uterus

1983 • 25 citations

Leukotriene D4 and E4 formation by plasma membrane bound enzymes

1984 • 17 citations

The multiple roles of the glutathione transferases (ligandins).

1979 • 17 citations

Double bond requirement for the 5-lipoxygenase pathway

1985 • 16 citations

Subcellular localization of leukotriene-forming enzymes.

1983 • 14 citations

Incorporation of radiolabel from [1-14C]5-hydroperoxy-eicosatetraenoic acid into slow reacting substance

1980 • 12 citations

Modulation of leukotriene formation by various acetylenic acids.

1982 • 3 citations