Production of Antisera by Conventional Techniques

Methods of Biochemical Analysis

1956 • 4,535 citations

IMMUNOASSAY OF ENDOGENOUS PLASMA INSULIN IN MAN

1960 • 2,983 citations

Methods of Hormone Radioimmunoassay

1978 • 2,097 citations

Radioimmunoassay for Cyclic Nucleotides

1972 • 2,057 citations

A METHOD FOR PRODUCING SPECIFIC ANTISERA WITH SMALL DOSES OF IMMUNOGEN

1971 • 1,376 citations

The Use of Esters of N-Hydroxysuccinimide in Peptide Synthesis

1964 • 1,214 citations

Methods in Immunology and Immunochemistry

1967 • 1,145 citations

The Specificity of Serological Reactions

1945 • 1,104 citations

Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution.

1975 • 932 citations

Advances in Prostaglandin and Thromboxane Research

1976 • 840 citations

Antibodies to Bradykinin and Angiotensin: A Use of Carbodiimides in Immunology

1964 • 820 citations

Radioimmunoassay of gastrin

1970 • 805 citations

STEROID-PROTEIN CONJUGATES

1957 • 798 citations

Basic and Clinical Immunology.

1979 • 790 citations

Radioimmunoassay of Plasma Progesterone

1971 • 691 citations

Advances in prostaglandin and thromboxane research

1980 • 675 citations

Glutaraldehyde as a protein cross-linking reagent

1968 • 542 citations

Principles of Competitive Protein-Binding Assays.

1972 • 522 citations

The Specificity of Serological Reactions

1945 • 484 citations

Radioimmunoassay of ACTH in plasma

1968 • 464 citations

ANTIBODIES SPECIFIC FOR RIBONUCLEOSIDES AND RIBONUCLEOTIDES AND THEIR REACTION WITH DNA

1964 • 452 citations

IMMUNOASSAY OF BOVINE AND HUMAN PARATHYROID HORMONE

1963 • 438 citations

Production and Evaluation of Antibodies for the Radioimmunoassay of Gastrin

1972 • 428 citations

Antigenicity: Some Molecular Aspects

1969 • 418 citations

A radioimmunoassay for plasma testosterone

1970 • 375 citations

Atrial natriuretic factor in rat hypothalamus, atria and plasma: Determination by specific radioimmunoassay

1984 • 362 citations

A Radioimmunoassay for Plasma Aldosterone¹

1970 • 336 citations

Enzyme Coupled Immunoassay of Insulin Using a Novel Coupling Reagent

1976 • 332 citations

A Radioimmunoassay for Cortisol in Plasma and Urine

1972 • 331 citations

Radioimmunoassay of Vasoactive Intestinal Polypeptide (VIP) in Plasma

1978 • 324 citations

A Radioimmunoassay for Gonadotropin-Releasing Hormone (Gn-RH) in Serum1

1973 • 302 citations

Glucagon: molecular physiology, clinical and therapeutic implications

1972 • 283 citations

An automatic pipette.

1951 • 272 citations

A Radioimmunoassay for Aldosterone in Human Peripheral Plasma Including a Comparison of Alternate Techniques

1972 • 269 citations

Adenosine 3′,5′ cyclic monophosphate assay at 10−15 mole level

1973 • 262 citations

Specificities of Prostaglandins B1, F1α, and F2α Antigen-Antibody Reactions

1971 • 260 citations

Guanosine 3' ,5'-Cyclic Monophosphate Assay at 10−15-Mole Level

1976 • 256 citations

Digoxin-specific antibodies.

1967 • 252 citations

The Preparation and Specificity of Antibody to Thyrotropin Releasing Hormone1

1972 • 245 citations

Characterization of antibodies of high affinity and specificity for the digitalis glycoside digoxin

1970 • 245 citations

Radioimmunoassay for Gastric Inhibitory Polypeptide

1974 • 239 citations

The measurement of digitoxin in human serum by radioimmunoassay

1968 • 232 citations

Radioimmunoassays for α-endorphin and β-endorphin

1977 • 231 citations

Radioimmunoassay for Prostaglandins

1971 • 224 citations

The simultaneous measurement of aldosterone, cortisol, and corticosterone in human peripheral plasma by displacement analysis.

1972 • 222 citations

Radioimmunoassay for neurotensin, a hypothalamic peptide.

1976 • 211 citations

A radioimmunoassay for leukotriene B4

1982 • 210 citations

Measuring leukotrienes of slow reacting substance of anaphylaxis: development of a specific radioimmunoassay.

1983 • 205 citations

PRINCIPLES FOR THE ASSESSMENT OF THE RELIABILITY OF RADIOIMMUNOASSAY METHODS (PRECISION, ACCURACY, SENSITIVITY, SPECIFICITY)

1969 • 198 citations

Specificity of antibodies to ovarian hormones in relation to the site of attachment of the steroid hapten to the peptide carrier

1972 • 196 citations

Methods in investigative and diagnostic endocrinology

1975 • 193 citations

Direct radioimmunoassay of atrial natriuretic factor

1984 • 192 citations

Basic and Clinical Immunology

1983 • 179 citations

Radioimmunoassays of Prostaglandins and Thromboxanes

1977 • 177 citations

Measurement of Plasma Aldosterone by Radioimmunoassay

1970 • 176 citations

Ca2+-dependent regulator. Production and characterization of a monospecific antibody.

1978 • 174 citations

A radioimmunoassay for 1,25-dihydroxycholecalciferol.

1980 • 168 citations

Peptides in Neurobiology

2011 • 153 citations

Reproducible production of antiserum against vertebrate calmodulin and determination of the immunoreactive site.

1981 • 149 citations

Radioimmunoassay for α-human and rat atrial natriuretic polypeptide

1984 • 137 citations

SPECIES-SPECIFICITY OF HUMAN ANTI-BEEF, PORK INSULIN SERUM

1959 • 137 citations

Modern Methods of Steroid Analysis

1973 • 133 citations

Mathematical Analysis of Kinetics of Radioligand Assays: Improved Sensitivity Obtained by Delayed Addition of Labeled Ligand

1971 • 127 citations

On the Formation of Covalent Linkages between Two Protein Molecules

1961 • 124 citations

Release of leukotriene C₄ from human polymorphonuclear leucocytes as determined by radioimmunoassay

1982 • 119 citations

Calmodulin. Production of an antibody in rabbit and development of a radioimmunoassay.

1979 • 118 citations

Radioimmunoassay of Arginine Vasopressin in Human Plasma

1971 • 116 citations

Clinical Aspects of Insulin–Antigenicity

1972 • 116 citations

A specific, non-chromatographic radioimmunoassay for human plasma cortisol

1975 • 111 citations

Preparation of derivatives of adenosine 3′,5′-phosphate

1967 • 110 citations

Radioimmunoassay in Gastroenterology

1972 • 110 citations

Introduction of sulfhydryl groups into proteins using acetylmercaptosuccinic anhydride

1962 • 110 citations

Antigenic activity of prostaglandins

1970 • 107 citations

Antigenic complexes of steroid hormones formed by coupling to protein through position 7: Preparation from Δ4 -3-oxosteroids and characterization of antibodies to testosterone and androstenedione

1972 • 102 citations

Two direct (nonchromatographic) assays for 25-hydroxyvitamin D.

1984 • 97 citations

Antibodies to Testosterone-3-Bovine Serum Albumin, Applied to Assay of Serum 17β-ol Androgens

1971 • 97 citations

Radioimmunoassay of the leukotrienes of slow reacting substance of anaphylaxis.

1981 • 96 citations

Cellular Site of Action of Various Adjuvants in Antibody Responses to Hapten-Carrier Conjugates

1973 • 94 citations

Specific visualization of the distribution of the calcium dependent regulatory protein of cyclic nucleotide phosphodiesterase (modulator protein) in tissue culture cells by immunofluorescence microscopy: mitosis and intercellular bridge.

1978 • 92 citations

Preparation of 17β-cestradiol-6-(0-carboxymethyl) oxime — bovine serum albumin conjugate

1971 • 90 citations

A radioimmunoassay for'plasma progesterone

1971 • 89 citations

Induction of Antibodies to Porcine ACTH in Rabbits with Nonsteroidogenic Polymers of BSA and ACTH

1968 • 88 citations

RECENT STUDIES ON INSULIN‐BINDING ANTIBODIES

1959 • 88 citations

HOMOLOGOUS RADIOIMMUNOASSAY FOR PLASMA-LEVELS OF CORTICOTROPHIN IN MAN

1968 • 85 citations

RADIOIMMUNOASSAY OF OXYTOCIN

1978 • 84 citations

Antibodies Specific for α‐N‐Acetyl‐β‐Endorphins: Radioimmunoassays and Detection of Acetylated β‐Endorphins in Pituitary Extracts

1982 • 77 citations

PRELIMINARY COMMUNICATION

1966 • 77 citations

Combined radioimmunoassay of four steroids in one ml of plasma: II. Androgens

1975 • 76 citations

Adrenocorticotropic Hormone (ACTH)

1978 • 76 citations

Immunogenicity of Insulin

1972 • 74 citations

A Sensitive Radioimmunoassay for Plasma ACTH Levels

1966 • 74 citations

Radioimmunoassay of prostaglandins

1978 • 73 citations

Use of Antibodies for Characterization of Gonadotropins and Steroids

1971 • 73 citations

Antigens in Insulin Determinants of Specificity of Porcine Insulin in Man

1963 • 70 citations

Radioimmunoassay of 17-hydroxyprogesterone

1972 • 70 citations

Radioimmunoassay of Plasma Estradiol Without Extraction and Chromatography

1975 • 68 citations

Antigenicity of Steroid-Protein Conjugates

1959 • 64 citations

A new phenomenon of usefulness in the radioimmunoassay of plasma adrenocorticotropic hormone.

1971 • 60 citations

Radioimmunoassay for urinary metabolites of prostaglandin F2α

1976 • 58 citations

Immunoassay of Protein Hormones

1964 • 58 citations

Inactivation of the Biological Effects of Exogenous and Endogenous Estrogens by Antibodies to 17β-Estradiol

1968 • 58 citations

Clinical Endocrinology.

1967 • 57 citations

The evolution of titer and specificity of aldosterone binding antibodies in hyperimmunized sheep

1972 • 56 citations

Production of Antibody against Bradykinin: Demonstration of Specificity by Complement Fixation and Radio-Immunoassay

1966 • 54 citations

Radioimmunoassay of Prostaglandin A

1973 • 54 citations

Characterization of antibody to prostaglandin F2α

1972 • 53 citations

Hapten-Radioimmunoassay for Steroid Hormones

1970 • 52 citations

N,N′-carbonyldiimidazole as coupling reagent for the preparation of bovine serum albumin conjugates

1974 • 50 citations

Determination of deoxycorticosterone in plasma; Double isotope and immunoassay methods

1971 • 50 citations

A Rapid Aldosterone Radioimmunoassay1

1972 • 49 citations

Radioligand assay for Δ5-3β-hydroxysteroids I. 3β-hydroxy-5-androstene-17-one and its 3-sulfate

1972 • 49 citations

Plasma Cortisone Concentration as Measured by Radioimmunoassay

1973 • 49 citations

Steroid glucuronoside-BSA complexes as antigens: The radioimmunoassay of steroid conjugates

1972 • 47 citations

A modified radioimmunoassay for 1,25-dihydroxycholecalciferol.

1981 • 46 citations

Immunochemical Studies with Lysine Vasopressin

1966 • 46 citations

Radioimmunoassay of Vasopressin with a Comparison of Immunological and Biological Activity in the Rat Posterior Pituitary

1969 • 45 citations

THE DEVELOPMENT OF A RADIOIMMUNOASSAY FOR OXYTOCIN: RADIO-IODINATION, ANTIBODY PRODUCTION AND SEPARATION TECHNIQUES

1970 • 44 citations

The immunological assay of drugs.

1977 • 43 citations

Antivasopressin antibody. Characterization of high-affinity rabbit antibody with limited association constant heterogeneity

1969 • 42 citations

SERUM-INSULIN OR PLASMA-INSULIN ?

1970 • 40 citations

Studies on the induction of antibody synthesis against sulfanilic acid in rabbits. 1. Effect of the number of hapten molecules introduced in homologous protein on antibody synthesis against the hapten and the new antigenic determinants

1972 • 39 citations

Radioimmunoassay of Vasoactive Intestinal Polypeptide in Plasma

1978 • 39 citations

Radioimmunoassay of Vasopressin: Application to Unextracted Human Urine

1971 • 39 citations

A radioimmunoassay for serum dehydroepiandrosterone sulfate

1972 • 38 citations

Radioimmunoassay for leukotriene B ₄

1982 • 38 citations

Radioimmunoassay of atropine in plasma.

1977 • 38 citations

Neutralization of Endogenous Glucagon by High Titer Glucagon Antiserum

1970 • 35 citations

Radioimmunoassay of plasma aldosterone.

1974 • 35 citations

Radioimmunoassay for Atropine and l‐Hyoscyamine

1980 • 34 citations

Radioimmunoassay of vasoactive intestinal peptide

1976 • 34 citations

Site of conjugation of bovine serum albumin to corticosteroid hormones and specificity of antibodies

1974 • 33 citations

[29] Preparation and use of specific antibodies for immunohistochemistry of neuropeptides

1983 • 31 citations

Immunochemical detection of prostaglandins with prostaglandin-coated bacteriophage T4 and by radioimmunoassay

1972 • 31 citations

Studies on the preparation of conjugates of leukotriene C4 with proteins for development of an immunoassay for SRS-A (1)

1982 • 30 citations

Synthesis of an antigenic copolymer of angiotensin and succinylated poly-l-lysine

1967 • 30 citations

GLUCAGON ANTIBODIES

1965 • 28 citations

Immunologic studies of octapeptides

1965 • 27 citations

Combined radioimmunoassay of four steroids in one ml of plasma: I. Progestins

1975 • 24 citations

INHIBITORY ACTION OF OESTROGEN ON CALCIUM-INDUCED MITOSIS IN RAT BONE MARROW AND THYMUS

1975 • 23 citations

Neurotensin and Related Substances

1978 • 22 citations

Preparation of specific antiserum to prostaglandin A

1972 • 20 citations

Preparation and specificity of antibodies to 15-keto-prostaglandin F2α

1972 • 19 citations

Immunologic studies on drug addiction. I. Antibodies reactive with methadone and their use for detection of the drug.

1973 • 18 citations

Development of a radiommunoassay for luteotropin releasing hormone (LRH) and thyrotropin releasing hormone (TRH)

1974 • 18 citations

Radioimmunoassay of gastrin in human serum using antiserum against pentagastrin.

1969 • 18 citations

Steroids as Immunochemical Probes, I. Influence of Oxo-, and/or Hydroxy-Groups at C-16/C-17 of Estrogens on Affinity to Anti-Estrone-, Anti-Estradiol-17α- and Anti-Estradiol-17β-Antisera

1973 • 17 citations

Synthesis of new steroid haptens for radioimmunoassay. Part IV. 3-O-carboxymethyl ether derivatives of estrogens. Specific antisera for radioimmunoassay of estrone, estradiol-17β, and estriol

1977 • 17 citations

Radioimmunoassay for 1,25-dihydroxycholecalciferol.

1983 • 16 citations

Development of a radioimmunoassay for Pro-Leu-Gly-NH2 (PLG or MIF-I): Evidence that PLG is not present in rat brain

1982 • 12 citations

EFFECT OF ANTIGENIC STRUCTURE ON ANTIBODY BIOSYNTHESIS *

1971 • 11 citations

Immunogenicity of lowly and highly derivatized dinitrophenyl-bovine gamma-globulin in different strains of guinea pigs.

1974 • 10 citations

Immunologic Studies on Drug Addiction

1973 • 10 citations

Specificity of prostaglandin A₁ antiserum Against prostaglandins A₁ and B₁*

1973 • 10 citations

Production of Anti-glucagon Antibodies in Poly-L-lysine “Responder” Guinea-pigs

1971 • 9 citations

International Atomic Energy Agency

2011 • 8 citations

KINETICS OF ANTIBODY FORMATION AND REGULATORY ASPECTS OF IMMUNITY

1975 • 8 citations

[28] Strategies for the preparation of haptens for conjugation and substrates for iodination for use in radioimmunoassay of small oligopeptides

1983 • 8 citations

Radioimmunoassay of Nortestosterone and Related Steroids

1979 • 8 citations

Immunogenicity of Lowly and Highly Derivatized Dinitrophenyl-Bovine γ-Globulin in Different Strains of Guinea Pigs

1974 • 7 citations

Stereospecific antibodies to methadone. I. Radioimmunoassay of d,l-methadone in human serum.

1977 • 6 citations

Specific Problems in the Identification and Quantitation of Neuropeptides by Radioimmunoassay

1977 • 6 citations

[49] A pyridoxamine phosphate derivative

1977 • 6 citations

Production of antisera specific to aldosterone: Effect of hapten density and of carrier proteins

1974 • 5 citations

Investigations into the immune response to steroid conjugates using corticoids as a model. I. A specific cortisol antibody.

1973 • 5 citations

Induction of Anti-Hapten Antibody Responses Against Haptens Conjugated to Autologous and Heterologous Proteins

1973 • 4 citations

Synthesis of Succinoyl and Phthaloyl Derivatives of Digitoxigenin, Gitoxigenin, and Oleandrigenin

1959 • 3 citations

Studies on Antibody to Bradykinin

1970 • 3 citations

Stereospecific antibodies to methadone. II. Synthesis of d- and 1-methadone antigens.

1978 • 2 citations