Mercapturic Acid Conjugation

An enzyme from rat liver catalysing conjugations with glutathione

1961 • 563 citations

Industrial Hygiene and Toxicology

1950 • 486 citations

Industrial Hygiene and Toxicology

1964 • 386 citations

Relative Nucleophilic Reactivities of Amino Groups and Mercaptide Ions in Addition Reactions with α,β-Unsaturated Compounds^1,2

1965 • 326 citations

Enzyme-catalysed conjugations of glutathione with unsaturated compounds

1967 • 324 citations

The role of arene oxide-oxepin systems in the metabolism of aromatic substrates. III. Formation of 1,2-naphthalene oxide from naphthalene by liver microsomes

1968 • 222 citations

AN ENZYME CATALYSING THE CONJUGATION OF EPOXIDES WITH GLUTATHIONE

1965 • 188 citations

Biochemical studies of toxic agents. 11. The occurrence of premercapturic acids

1958 • 173 citations

The Peroxide Effect in the Addition of Reagents to Unsaturated Compounds and in Rearrangement Reactions.

1940 • 162 citations

The chemistry of alkenes

1964 • 161 citations

A LIVER ENZYME THAT CONJUGATES SULFOBROMOPHTHALEIN SODIUM WITH GLUTATHIONE*

1961 • 155 citations

RENOTROPIC CHARACTERISTICS OF ETHACRYNIC ACID: A PHENOXYACETIC SALURETIC-DIURETIC AGENT.

1965 • 154 citations

Studies on glutathione S-alkyltransferase of the rat

1966 • 153 citations

Studies in detoxication

1940 • 151 citations

The Reaction of Glutathione with Amino Acids and Related Compounds as Catalyzed by γ-Glutamyl Transpeptidase

1959 • 133 citations

Nature of a Soluble, Glutathione-Dependent Enzyme System Active in Cleavage of Methyl Parathion to Desmethyl Parathion

1966 • 130 citations

Studies on Quinone-Thioethers. I. Mechanism of Formation and Properties of Thiodione^*

1963 • 130 citations

The metabolism of benz[a]anthracene and dibenz[a,h]anthracene and their 5,6-epoxy-5,6-dihydro derivatives by rat-liver homogenates

1965 • 129 citations

The Mechanism of the Antibiotic Action of Clavacin and Penicillic Acid^1,2

1945 • 128 citations

Enzymes catalysing conjugations of glutathione with αβ-unsaturated carbonyl compounds

1968 • 126 citations

The Flavor of Cucumbers

1962 • 125 citations

Oral, subcutaneous and intratracheal administration of carcinogenic lactones and related substances: the intratracheal administration of cigarette tar in the rat.

1966 • 124 citations

Abnormal Sulphatase Activities in Two Human Diseases (Metachromatic Leucodystrophy and Gargoylism)

1964 • 121 citations

Reactions of Mercaptans with Acrylic and Methacrylic Derivatives

1947 • 119 citations

THE METABOLISM OF URETHANE AND RELATED COMPOUNDS

1965 • 114 citations

The formation of mercapturic acids. 1. Formation of mercapturic acid and the levels of glutathione in tissues

1959 • 112 citations

The metabolism of 3-methylcholanthrene and some related compounds by rat-liver homogenates

1966 • 106 citations

POLYCYCLIC HYDROCARBONS

1964 • 104 citations

The Importance of Conjugation with Glutathione for Sulfobromophthalein Sodium (BSP) Transfer from Blood to Bile*

1965 • 103 citations

Studies in detoxication. 62. The metabolism of halogenobenzenes. Ortho- and para-dichlorobenzenes

1955 • 100 citations

Conjugations with glutathione. Distribution of glutathione S-aryltransferase in vertebrate species

1964 • 98 citations

The transformation of glyceryl trinitrate and other nitrates by glutathione-organic nitrate reductase.

1965 • 96 citations

Acidic peptides of the lens

1956 • 91 citations

METABOLISM OF INORGANIC NITRITE AND NITRATE ESTERS

1950 • 90 citations

Metabolism of bis-β-chloroethyl sulfide (sulfur mustard gas)

1961 • 87 citations

The metabolism of naphthalene in rabbits

1934 • 87 citations

Studies in detoxication. 66. The metabolism of halogenobenzenes. 1:2:3-, 1:2:4- and 1:3:5-trichlorobenzenes

1955 • 87 citations

Ueber die nach Einführung von Brombenzol und Chlorbenzol im Organismus entstehenden schwefelhaltigen Säuren

1879 • 87 citations

Ueber Bromphenylmercaptursäure

1879 • 85 citations

Metabolism of polycyclic compounds. 24. The metabolism of benz[α]anthracene

1964 • 84 citations

Arylnitroalkenes: A New Group of Antibacterial Agents¹

1952 • 83 citations

Metabolism of polycyclic compounds. 23. The metabolism of pyrene in rats and rabbits

1964 • 83 citations

The formation of mercapturic acids. 2. The possible role of glutathionase

1959 • 83 citations

The metabolism of phenethyl bromide, styrene and styrene oxide in the rabbit and rat

1967 • 81 citations

The metabolism of 3,5-di-tert.-butyl-4-hydroxytoluene in the rat and in man

1968 • 80 citations

The influence of some aliphatic compounds on rat liver glutathione levels

1965 • 80 citations

The metabolism of pentachloronitrobenzene and 2:3:4:6-tetrachloronitrobenzene and the formation of mercapturic acids in the rabbit

1955 • 78 citations

IDENTIFICATION OF METABOLITES OF SULFOBROMOPHTHALEIN *

1959 • 78 citations

The biotransformation of a sulfonamide to a mercaptan and to mercapturic acid and glucuronide conjugates

1965 • 78 citations

The formation of mercapturic acids. 3. N-Acetylation of S-substituted cysteines in the rabbit, rat and guinea pig

1959 • 78 citations

Biochemical studies of toxic agents. 15. The biosynthesis of ethylmercapturic acid sulphoxide

1964 • 78 citations

Metabolism of polycyclic compounds. 12. An acid-labile precursor of 1-naphthylmercapturic acid and naphthol: an N-acetyl-S- (1:2-dihydrohydroxynaphthyl)-<scp>l</scp>-cysteine

1958 • 77 citations

The biochemistry of aromatic amines. The metabolism of 2-naphthylamine and 2-naphthylhydroxylamine derivatives

1966 • 74 citations

Comparative detoxication. 10. The enzymic conjugation of chloro compounds with glutathione in locusts and other insects

1964 • 73 citations

CARCINOGENIC LACTONES AND RELATED SUBSTANCES

1964 • 71 citations

Mercapturic acid formation during the metabolism of arecoline and arecaidine in the rat

1969 • 71 citations

Some Organic Sulfur Compounds in Vegetables and Fodder Plants and their Significance in Human Nutrition

1962 • 71 citations

Metabolism of polycyclic compounds. 18. The secretion of metabolites of naphthalene, 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene in rat bile

1961 • 71 citations

Substances in Mulberry Leaves which attract Silkworm Larvæ (Bombyx mori)

1958 • 70 citations

Metabolism of polycyclic compounds. 26. The hydroxylation of some aromatic hydrocarbons by the ascorbic acid model hydroxylating system and by rat-liver microsomes

1964 • 70 citations

Metabolism of polycyclic compounds. 17. The reaction of 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene with glutathione catalysed by tissue preparations

1960 • 68 citations

The distribution of urethane in animal tissues, as determined by a microdiffusion method, and the effect of urethane treatment on enzymes

1949 • 68 citations

Studies on the mode of action of tumour-growth-inhibiting alkylating agents—I

1958 • 66 citations

The fate of diphenyl in the rat

1956 • 66 citations

An enzyme from rat liver catalysing conjugations with glutathione. 2. Replacement of nitro groups

1963 • 66 citations

The metabolism of some aromatic hydrocarbons by mouse embryo cell cultures

1970 • 65 citations

Metabolism of iodomethane in the rat

1966 • 65 citations

Species differences in the inhibition of glutathione S-aryltransferase by phthaleins and dicarboxylic acids

1967 • 65 citations

Glutathione S-aralkyltransferase

1969 • 64 citations

Species variation in metabolism, storage, and excretion of sulfobromophthalein

1967 • 63 citations

The metabolism of 7- and 12-methylbenz[a]-anthracene and their derivatives

1967 • 61 citations

The metabolism of acetophenetidine. Isolation and characterization of S-(1-acetamido-4-hydroxyphenyl)-cysteine, a metabolite of acetophenetidine

1964 • 60 citations

Metabolism of polycyclic compounds. 15. The conversion of naphthalene into a derivative of glutathione by rat-liver slices

1960 • 59 citations

Metabolism of some ω-halogenoalkylbenzenes and related alcohols in the rabbit

1958 • 58 citations

Biochemical studies of toxic agents. The metabolism of 1- and 2-bromopropane in rats

1966 • 58 citations

DETOXIFICATION IN THE NEWBORN: THE ABILITY OF THE NEWBORN INFANT TO FORM CONJUGATES WITH GLUCURONIC ACID, GLYCINE, ACETATE AND GLUTATHIONE

1963 • 57 citations

Metabolism of polycyclic compounds. 16. The metabolism of 1:2-dihydronaphthalene and 1:2-epoxy-1:2:3:4-tetrahydronaphthalene

1960 • 56 citations

METABOLISM OF POLYCYCLIC COMPOUNDS. THE METABOLISM OF 9,10-EPOXY-9,10-DIHYDROPHENANTHRENE IN RATS

1965 • 55 citations

The Fungistatic Activity of Ethylenic and Acetylenic Compounds

1948 • 55 citations

The metabolism of 2:3:5:6- and 2:3:4:5-tetrachloronitrobenzenes in the rabbit and the reduction of aromatic nitro compounds in the intestine

1953 • 55 citations

The metabolism of the monochloronitrobenzenes in the rabbit

1956 • 55 citations

Phosphoric acid triester–glutathione alkyltransferase. A mechanism for the detoxification of dimethyl phosphate triesters

1972 • 54 citations

The metabolism of S-methyl-l-cysteine in the rat

1964 • 53 citations

Formation of mercapturic acids. 5. Metabolism of some halogenoparaffins and nitroparaffins

1964 • 53 citations

Studies in detoxication. 34. The metabolism of chlorobenzene in the rabbit. Isolation of dihydrodihydroxychlorobenzene, p-chlorophenylglucuronide, 4-chlorocatechol glucuronide and p-chlorophenylmercapturic acid

1950 • 52 citations

Studies in detoxication. 63. The metabolism of halogenobenzenes. (a) Meta-dichlorobenzene. (b) Further observations on the metabolism of chlorobenzene

1955 • 52 citations

THE BILIARY EXCRETION OF SULFOBROMOPHTHALEIN SODIUM (BSP) IN THE RAT AS A CONJUGATE OF GLYCINE AND GLUTAMIC ACID *†

1959 • 51 citations

The metabolism of 2-chloro-1-(2′,4′-dichlorophenyl)vinyl diethyl phosphate (Chlorfenvinphos) in the dog and rat

1967 • 50 citations

Studies in detoxication. 33. The metabolism of halogenobenzenes. A comparison of the glucuronic acid, ethereal sulphate and mercapturic acid conjugations of chloro-, bromo- and iodo-benzenes and of the o-, m- and p-chlorophenols. Biosynthesis of o-, m- and p-chlorophenylglucuronides

1950 • 47 citations

The metabolism of S-methyl-<scp>l</scp>-cysteine

1968 • 47 citations

Acidic peptides of the lens. 8. S-(α β-dicarboxyethyl) glutathione

1963 • 46 citations

Metabolism of polycyclic compounds. 20. The metabolism of phenanthrene in rabbits and rats: mercapturic acids and related compounds

1962 • 46 citations

The biochemistry of aromatic amines. 9. Mercapturic acids as metabolites of aniline and 2-naphthylamine

1963 • 46 citations

Metabolism of polycyclic compounds

1936 • 44 citations

1,2‐Naphthalene Oxide

1968 • 43 citations

Comparative detoxication. 9. The metabolism of some halogenated compounds by conjugation with glutathione in the locust

1964 • 42 citations

STUDIES IN HEPATIC FUNCTION. VI A. THE PHARMACOLOGICAL BEHAVIOR OF CERTAIN PHTHALEIN DYES B. THE VALUE OF SELECTED PHTHALEIN COMPOUNDS IN THE ESTIMATION OF HEPATIC FUNCTION

1924 • 41 citations

The formation of 2-hydroxypropylmercapturic acid from 1-halogenopropanes in the rat

1966 • 41 citations

METABOLISM OF CHLORINATED NAPHTHALENES

1958 • 40 citations

Fungistatic Activity of Ethylenic and Acetylenic Compounds

1946 • 39 citations

The biosynthesis of phenols. 5. The relationships of some phenolic metabolites of mutants of Aspergillus terreus Thom, I.M.I. 16043

1964 • 38 citations

Biochemical studies of toxic agents. 14. The biosynthesis of ethylmercapturic acid

1963 • 38 citations

Nucleophilic attacks on carbon-carbon double bonds

2010 • 37 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1938 • 36 citations

Some metabolites of 1-bromobutane in the rabbit and the rat

1968 • 35 citations

THE FATE OF FOREIGN ORGANIC COMPOUNDS IN THE ANIMAL BODY

1922 • 35 citations

BIOCHEMICAL STUDIES OF TOXIC AGENTS. THE METABOLISM OF IODOMETHANE

1965 • 35 citations

Metabolic and Chemical Studies of ‘Myleran’: Formation of 3-Hydroxytetrahydrothiophene-1,1-Dioxide In Vivo, and Reactions With Thiols In Vitro

1959 • 34 citations

The metabolism of 2:4-, 2:5- and 3:4-dichloronitrobenzene in the rabbit

1957 • 33 citations

Tumor initiatory activity of some chloromononitrobenzenes and other compounds.

1966 • 32 citations

Improvements to the ultraviolet-absorption optical system of an ultracentrifuge

1963 • 31 citations

CONJUGATIONS WITH GLUTATHIONE. THE ENZYMIC CONJUGATION OF SOME CHLOROCYCLOHEXENES

1965 • 30 citations

Metabolism of the herbicide 2,6-dichlorobenzonitrile in rabbits and rats

1966 • 30 citations

Observations on the metabolism of allyl compounds in the rat

1969 • 29 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1937 • 29 citations

Renal Pharmacology

1966 • 28 citations

The Antibacterial Properties of Dicumarol

1945 • 28 citations

Structure of a new sulfur-containing amino acid

1962 • 28 citations

MERCAPTURIC ACID PRECURSORS

1956 • 25 citations

S-(1-2-dicarboxyethyl)cysteine in urine and kidney

1966 • 25 citations

SYNTHESIS OF SOME ARYL-SUBSTITUTED l-CYSTEINES AND THEIR FATE IN THE ANIMAL BODY

1954 • 25 citations

The metabolism of 2:3-, 2:6- and 3:5-dichloronitrobenzene and the formation of a mercapturic acid from 2:3:4:5-tetrachloronitrobenzene in the rabbit

1957 • 25 citations

Biochemical studies of toxic agents. The metabolic formation of 1- and 2-menaphthylmercapturic acid

1968 • 25 citations

The biochemistry of aromatic amines. 2-Formamido-1-naphthyl hydrogen sulphate, a metabolite of 2-naphthylamine

1966 • 24 citations

Enzymatic glutathione conjugations with 2,3-epoxyphenylpropylether and diethylmaleate by wild bird liver supernatant

1968 • 24 citations

Fruit aromas: a survey of components identified.

1967 • 24 citations

Isolation of S-(carboxymethyl)cystein from urine

1967 • 22 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1938 • 21 citations

The relationship between hepatic glutathione conjugation and BSP excretion and the effect of therapeutic agents

1967 • 21 citations

Role of Milk Lipids in Flavors of Dairy Products

1969 • 21 citations

Metabolism of o-, m- and p-fluoro-, -bromo- and -iodo-nitrobenzenes in the rabbit

1958 • 21 citations

Differential glutathione-dependent detoxication of two geometrical vinyl organophosphorus (mevinphos) isomers

1967 • 19 citations

Biochemical studies of toxic agents. 10. Observations on the metabolism of 35S-labelled mercapturic acids

1958 • 19 citations

Comparitive study of monocarbonyl compounds formed during deep frying in different fats

1965 • 19 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1939 • 18 citations

Complete oxidation of maleic acid via d(+)malate in kidney

1962 • 18 citations

The metabolism of the trichloronitrobenzenes in the rabbit

1957 • 18 citations

LABORATORY SYNTHESIS OF p-CHLOROPHENYL-l-CYSTEINE AND ITS ACETYLATION BY THE RAT

1951 • 17 citations

Studies on Mercapturic Acids

1966 • 17 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1941 • 16 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1937 • 16 citations

Die Ausscheidung von Esterschwefelsäure beim Kaninchen nach Verfütterung von Phenol, Bromphenol und Brombenzol.

1923 • 15 citations

The effect of bromobenzene and 3,4-benzpyrene on the metabolism of radioactive L-cystine.

1950 • 15 citations

Mercapturic acid formation and enzyme-catalyzed conjugations with glutathione in pigeons

1969 • 15 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS XII. THE SYNTHESIS OF N-ACETYL-S-p-BROMOBENZYL-l-CYSTEINE IN THE RAT FROM p-BROMOBENZYL BROMIDE, S-p-BROMOBENZYL-l-CYSTEINE, AND S-p-BROMOBENZYLGLUTATHIONE

1941 • 15 citations

A NOTE ON THE ACETYLATION OF SULFUR AMINO ACIDS BY LIVER AND KIDNEY

1951 • 14 citations

Studies on the mercapturic acid synthesis in animals. 5. The effect of naphthalene on the growth of rats as related to diets of varying sulfur content.

1937 • 14 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1947 • 14 citations

Uncoiling of bacteriophage-φ X174 replicative form deoxyribonucleic acid by ethidium, daunomycin and actinomycin

1968 • 13 citations

CHEMISCHE UNTERSUCHUNGEN ÜBER DIE ENTSTEHUNG DES NAPHTALIN KATARARTS

1934 • 13 citations

METABOLISM OF IODOBENZENE

1953 • 13 citations

Beiträge zur Entgiftung im tierischen Organismus

1930 • 12 citations

Biosynthesis of isovalthine precursor in liver homogenates

1963 • 12 citations

Conversion of S-benzylglutathione to Benzylmercapturic Acid in the Rat.

1940 • 11 citations

Studies on Mercapturic Acids. Investigation of Glutathione-conjugating Enzyme by the Method of Thin-layer Chromatography.

1967 • 11 citations

Coupled Reactions in Biological Systems

1933 • 11 citations

Studies on Mercapturic Acids&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;*&lt;/sup&gt;&lt;/xref&gt;&lt;subtitle&gt;Effect of Some Aromatic Compounds on the Level of Glutathione and the Activity of Glutathionase&lt;xref ref-type="fn" rid="fn2"&gt;&lt;sup&gt;**&lt;/sup&gt;&lt;/xref&gt; in the Rat&lt;/subtitle&gt;

1966 • 10 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1946 • 10 citations

MERCAPTURIC ACIDS

1943 • 10 citations

The metabolism of halogenobenzenes

1953 • 10 citations

Second International Pharmacological Meeting

1966 • 10 citations

FORMATION OF MERCAPTURIC ACIDS BY CYSTINURIC AND NORMAL DOGS

1949 • 9 citations

The metabolism of thiophen and benzo(b)thiophen

1968 • 9 citations

Sedimentation, viscosity and partial specific volumes of membrane proteins and lipoproteins

1967 • 9 citations

Loss of Coding Properties of the Oligonucleotide Adenylyluridylylguanosine after Photoreduction or Hydration

1967 • 9 citations

Enzymatic Cleavage of S-(Isopropylcarboxymethyl) Glutathione into Isovalthine*

1965 • 9 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1937 • 8 citations

REACTIONS OF THIOLS WITH UNSATURATED COMPOUNDS

1954 • 8 citations

285 Mercapturic acid conjugation

1961 • 8 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1937 • 8 citations

Mode of Action of Drugs

1964 • 7 citations

Studies on mercapturic acid synthesis by humans

1963 • 6 citations

STUDIES ON THE MERCAPTURIC ACID SYNTHESIS IN ANIMALS

1939 • 6 citations

Studies on the mercapturic acid synthesis in animals. 6. The dependence of the extent of the synthesis of p-bromophenylmercapturic acid in dogs on the body weight.

1937 • 6 citations

Some metabolites of bromocyclopentane, bromocyclohexane and bromocycloheptane in the rabbit

1970 • 6 citations

The metabolism of 3:4-dichloronitrobenzene in the rabbit with special reference to the formation of mercapturic acids.

1955 • 6 citations

Studies on the mereapturic acid synthesis in animals 10. Glutathione in relation to growth of rats on a low casein diet which cotained bromebipscoe and naphthalane.

1939 • 4 citations

The fate of mercapturic acids in the animal body.

1962 • 3 citations

[Effect of kidney homogenates on the reaction of glutathione with maleic acid].

1961 • 3 citations

S-(beta-carboxy-n-propyl)-L-cysteine and S-(beta-carboxyethyl)-L-cysteine in urine.

1965 • 3 citations

Deleted Work

1955 • 0 citations