Antigen Recognition by B and T Lymphocytes

Plaque Formation in Agar by Single Antibody-Producing Cells

1963 • 2,385 citations

The clonal selection theory of acquired immunity

1959 • 2,008 citations

The clonal selection theory of acquired immunity

1959 • 1,576 citations

An enzymic method for the trace iodination of immunoglobulins and other proteins

1969 • 1,414 citations

IMMUNOLOGICAL FUNCTION OF THE THYMUS

1961 • 1,359 citations

Redistribution and Pinocytosis of Lymphocyte Surface Immunoglobulin Molecules Induced by Anti-Immunoglobulin Antibody

1971 • 1,093 citations

The somatic generation of immune recognition

1971 • 974 citations

THE NATURAL-SELECTION THEORY OF ANTIBODY FORMATION

1955 • 700 citations

The carrier effect in the secondary response to hapten‐protein conjugates. II. Cellular cooperation

1971 • 677 citations

CELL TO CELL INTERACTION IN THE IMMUNE RESPONSE

1968 • 668 citations

CELL TO CELL INTERACTION IN THE IMMUNE RESPONSE

1968 • 639 citations

Thymus-Marrow Cell Combinations. Synergism in Antibody Production.

1966 • 613 citations

Cell Selection by Antigen in the Immune Response

1969 • 594 citations

Developmental aspects of antibody formation and structure

1972 • 466 citations

Enzymic iodination. A probe for accessible surface proteins of normal and neoplastic lymphocytes

1971 • 464 citations

The dynamic state of the lymphocyte membrane. Factors affecting the distribution and turnover of surface immunoglobulins

1972 • 450 citations

Theta Isoantigen as a Marker of Thymus-derived Lymphocytes in Mice

1969 • 449 citations

THE REQUIREMENT OF MORE THAN ONE ANTIGENIC DETERMINANT FOR IMMUNOGENICITY

1969 • 412 citations

THE CELLULAR BASIS OF IMMUNOLOGICAL RESPONSES

1969 • 396 citations

CELL SURFACE IMMUNOGLOBULIN

1971 • 380 citations

Cell Sorting: Automated Separation of Mammalian Cells as a Function of Intracellular Fluorescence

1969 • 376 citations

Thymus and Antigen‐Reactive Cells

1969 • 345 citations

THE IMMUNOLOGICAL ROLE OF DIFFERENT LYMPHOID ORGANS IN THE CHICKEN

1962 • 341 citations

CELL SEPARATION ON ANTIGEN-COATED COLUMNS

1969 • 320 citations

The carrier effect in the secondary response to hapten‐protein conjugates. I. Measurement of the effect with transferred cells and objections to the local environment hypothesis

1971 • 319 citations

Surface Antigenic Markers for Distinguishing T and B Lymphocytes in Mice

1971 • 295 citations

Role of Thymus-derived Lymphocytes in the Secondary Humoral Immune Response in Mice

1970 • 280 citations

Interaction between lymphocytes in immune responses

1971 • 244 citations

Immunologic Complementation between Thymus and Marrow Cells—A Model for the Two‐Cell Theory of Immunocompetence

1969 • 240 citations

A THREE-CELL INTERACTION REQUIRED FOR THE INDUCTION OF THE PRIMARY IMMUNE RESPONSE in vitro

1968 • 237 citations

THE FAILURE OF THYMUS-DERIVED CELLS TO PRODUCE ANTIBODY

1967 • 233 citations

CELL TO CELL INTERACTION IN THE IMMUNE RESPONSE

1968 • 229 citations

Specific Inactivation of Antigen-reactive Cells with 125I-Labelled Antigen

1969 • 228 citations

An in vitro reaction between labelled flagellin or haemocyanin and lymphocyte-like cells from normal animals.

1969 • 225 citations

Allergy and Immunology

1957 • 222 citations

Specific Inactivation of Thymus-derived (T) and Non-thymus-derived (B) Lymphocytes by 125I-labelled Antigen

1971 • 221 citations

CELL POPULATIONS AND CELL PROLIFERATION IN THE IN VITRO RESPONSE OF NORMAL MOUSE SPLEEN TO HETEROLOGOUS ERYTHROCYTES

1967 • 218 citations

Mediators of Cellular Immunity.

1970 • 215 citations

Skin Homograft Survival in Thymectomized Mice.

1962 • 211 citations

Antigen Recognition Responsible for the Induction In Vitro of the Secondary Response

1967 • 207 citations

QUANTITATIVE FEATURES OF A SANDWICH RADIOIMMUNOLABELING TECHNIQUE FOR LYMPHOCYTE SURFACE RECEPTORS

1972 • 204 citations

IMMUNOGLOBULIN AND OTHER SURFACE ANTIGENS OF CELLS OF THE IMMUNE SYSTEM

1971 • 197 citations

STUDIES ON GLOBULIN AND ANTIBODY PRODUCTION IN MICE THYMECTOMIZED AT BIRTH.

1964 • 194 citations

A RECEPTOR FOR ANTIBODY ON B LYMPHOCYTES

1972 • 192 citations

A Simple Method for detecting Single Antibody-forming Cells

1964 • 188 citations

Preparation and characterization of the plasma membrane of pig lymphocytes

1970 • 188 citations

The Thymus and the Cellular Basis of Immunity

1969 • 188 citations

THE BEHAVIOR OF HAPTEN-POLY-<scp>L</scp>-LYSINE CONJUGATES AS COMPLETE ANTIGENS IN GENETIC RESPONDER AND AS HAPTENS IN NONRESPONDER GUINEA PIGS

1966 • 183 citations

Glycoprotein Receptors for Concanavalin A isolated from Pig Lymphocyte Plasma Membrane by Affinity Chromatography in Sodium Deoxycholate

1972 • 175 citations

Cell Fractionation and Arrangement on Fibers, Beads, and Surfaces

1971 • 168 citations

Current topics in microbiology and immunology

1971 • 154 citations

Tissue Localization of Lymphocytes Bearing a Membrane Receptor for Antigen-Antibody-Complement Complexes

1970 • 152 citations

Binding of Radioiodinated Bovine Serum Albumin to Mouse Spleen Cells

1967 • 147 citations

Frequency of antigen-sensitive cells to thymus-independent antigens

1971 • 140 citations

Studies on antigen-binding cells

1970 • 140 citations

Studies on Actively Allergized Cells

1969 • 130 citations

The immunoglobulin nature of the antigen recognition site on cells mediating transplantation immunity and delayed hypersentivity.

1970 • 129 citations

Immunological Specificity of the Secondary Response with Dinitrophenylated Proteins.

1963 • 129 citations

Blocking of the Lymphocyte Antigen Receptor Site with Anti-immunoglobulin Sera in vitro

1970 • 129 citations

Mediators of cellular immunity.

1973 • 126 citations

SEPARATION OF NORMAL AND IMMUNE LYMPHOID CELLS BY ANTIGEN-COATED COLUMNS

1970 • 124 citations

THE FUNCTIONAL DISSECTION OF AN ANTIGEN MOLECULE: SPECIFICITY OF HUMORAL AND CELLULAR IMMUNE RESPONSES TO GLUCAGON

1971 • 123 citations

THE FREQUENCY OF ANTIGEN-SENSITIVE CELLS IN TISSUE TRANSPLANTATION

1969 • 119 citations

RECEPTORS ON IMMUNOCOMPETENT CELLS

1971 • 118 citations

LYMPHOCYTE MEMBRANE DYNAMICS

1971 • 118 citations

Cellular Cooperation in the Antibody Response of Mice to Two Serum Albumins: Specific Function of Thymus Cells

1969 • 117 citations

Studies on cytophilic antibodies. 1. The production by mice of macrophage cytophilic antibodies to sheep erythrocytes: relationship to the production of other antibodies and the development of delayed-type hypersensitivity.

1967 • 113 citations

Isolation of Heavy and Light Chains of Immunoglobulin from the Surfaces of Lymphoid Cells

1971 • 112 citations

Specific Separation of Cells on Affinity Columns

1970 • 111 citations

Antibody-mediated activation of a defective beta-D-galactosidase extracted from an Escherichia coli mutant.

1968 • 107 citations

Receptor for Antibody—Antigen Complexes used to Separate T Cells from B Cells

1972 • 106 citations

A kinetic study of antibody producing cells in the spleen of mice immunized intravenously with sheep erythrocytes.

1968 • 105 citations

The Immunoglobulin Nature of the Antigen Recognition Site on Cells Mediating Transplantation Immunity and Delayed Hypersensitivity

1970 • 99 citations

Antigen Binding Cells in Tolerance and Immunity

1970 • 97 citations

The Elusive T Cell Receptor

1972 • 96 citations

ANTIGEN RECOGNITION AND THE IMMUNE RESPONSE

1972 • 95 citations

Evidence for surface‐associated immunoglobulin on T and B lymphocytes

1971 • 93 citations

SURFACE IMMUNOGLOBULINS ON THYMUS AND THYMUS-DERIVED LYMPHOID CELLS

1971 • 92 citations

CELL SURFACE IMMUNOGLOBULIN

1974 • 91 citations

Antibody Production by Isolated Spleen Cells: A Study of the Cluster and the Plaque Techniques

1968 • 91 citations

DEMONSTRATION OF HEAVY AND LIGHT CHAIN ANTIGENIC DETERMINANTS ON THE CELL-BOUND RECEPTOR FOR ANTIGEN

1970 • 91 citations

Biological Effects of Anti‐Immunoglobulins

1970 • 90 citations

Cell cooperation in antibody induction. The susceptibility of helper cells to specific lethal radioactive antigen

1971 • 86 citations

SOME PHYSICAL AND RADIOBIOLOGICAL PROPERTIES OF IMMUNOLOGICALLY REACTIVE MOUSE SPLEEN CELLS

1970 • 83 citations

STUDIES ON CYTOPHILIC ANTIBODIES.

1967 • 78 citations

THE IMMUNE RESPONSE TO A HYBRID PROTEIN MOLECULE

1967 • 78 citations

Isolation of Surface Immunoglobulin from Lymphocytes from Human and Murine Thymus

1972 • 77 citations

Measurement of antibody-producing capacity in man. I. The normal response to flagellin from Salmonella adelaide.

1969 • 75 citations

ANTIGEN-REACTIVE CELLS IN NORMAL, IMMUNIZED, AND TOLERANT MICE

1969 • 75 citations

Correlation of grain counts with radioactivity (125I and tritium) in autoradiography

1966 • 74 citations

Antigen Recognition and the Immune Response: the Capacity of L-Tyrosine-Azobenzenearsonate to Serve as a Carrier for a Macromolecular Hapten

1971 • 72 citations

Regulation of antibody response in vitro. IV. Heavy chain antigenic determinants on hapten-specific memory cells.

1972 • 68 citations

Studies on antigen-binding cells

1970 • 67 citations

RECEPTORS ON IMMUNOCOMPETENT CELLS

1971 • 67 citations

Cell Separation on Affinity Columns: The Preparation of Pure Populations of Anti-Hapten Specific Lymphocytes

1971 • 65 citations

Tolerance Specificity and the Immune Response to Lactic Dehydrogenase Isoenzymes

1967 • 63 citations

The relationship of antibody-forming cells to rosette-forming cells.

1971 • 62 citations

Studies on immunological paralysis. II. The detection and significance of antibod-forming cells in the spleen during immunological paralysis with type 3 pneumococcal polysaccharide.

1969 • 61 citations

Ontogeny of the Immune Response in Cold-Blooded Vertebrates

1973 • 61 citations

Specific Fractionation of Immunocompetent Cells

1970 • 60 citations

THE SIGNIFICANCE OF THE PROTEIN CARRIER IN THE STIMULATION OF DNA SYNTHESIS BY HAPTEN-PROTEIN CONJUGATES IN THE SECONDARY RESPONSE.

1964 • 58 citations

ANTIGEN-BINDING CELLS IN MICE IMMUNE OR TOLERANT TO ESCHERICHIA COLI POLYSACCHARIDE

1971 • 57 citations

Passive Sensitization of Tissue Cells

1967 • 56 citations

STUDIES ON CYTOPHILIC ANTIBODIES

1968 • 56 citations

ANTIGEN-BINDING LYMPHOCYTES IN HUMAN BLOOD

1970 • 54 citations

Immunoglobulin Determinants on the Surface of Antigen Binding T- and B-Lymphocytes in Mice

1971 • 54 citations

Identification of Two Cell Populations Required for Mouse Immunocompetence

1970 • 53 citations

The expression of immunoglobulin determinants on the surface of antigen‐binding lymphoid cells in mice. I. An analysis of light and heavy chain restrictions on individual cells

1971 • 53 citations

THE RESTORATION OF IMMUNOLOGICAL FUNCTION BY THYMUS GRAFTING IN THYMECTOMIZED IRRADIATED MICE

1965 • 53 citations

Cell Interaction in Antibody Synthesis

1970 • 51 citations

Functional Specificity of Antigen‐Binding Receptors of Lymphocytes

1970 • 50 citations

Enhanced stability against heat denaturation of E. coli wild type and mutant β-galactosidase in the presence of specific antibodies

1970 • 50 citations

The Activation of Mutant β‐Galactosidase by Specific Antibodies

1970 • 50 citations

Antigen-binding cells. I. Their idenification and role in the immune response.

1971 • 49 citations

Studies on the relation of a prior immune response to immunogenicity.

1967 • 48 citations

Antigen Receptor Molecules: Inhibition by Antiserum against Kappa Light Chains

1970 • 47 citations

Rosette Forming Cells in Non-immunized Mice

1968 • 47 citations

T and B rosette‐forming cells

1971 • 47 citations

A system for lymphocytes in the mouse

1971 • 45 citations

Cell Separation on Affinity Columns: The Isolation of Immunospecific Precursor Cells from Unimmunized Mice

1972 • 42 citations

Specific Blocking in vitro of Antibody Synthesis by Affinity Labelling Reagents

1969 • 42 citations

Antigen Binding Cells in Tolerant Animals

1970 • 42 citations

Binding of &lt;sup&gt;125&lt;/sup&gt;I-BSA to Lymphoid Cells of Tolerant Mice

1969 • 39 citations

A morphological examination of antigen reactive cells from mouse spleen and peritoneal cavity

1969 • 38 citations

Macrophage cytophilic antibody in mice. Differentiation between antigen adherence due to these antibodies and opsoni adherence.

1969 • 36 citations

Ontogeny of the immune response in animals having less than one million lymphocytes: the larvae of the toad Alytes obstetricans.

1970 • 36 citations

Receptors for Immunoglobulin and Complement on Mouse Leukemias and Lymphomas

1972 • 36 citations

Passive Sensitization of Tissue Cells

1965 • 36 citations

Analogies Between Lymphocyte Receptors and the Resulting Humoral Antibodies

1970 • 34 citations

Antigen-Binding Cells in Normal Mouse Thymus

1970 • 34 citations

Measurement of Antibody-Producing Capacity in Man

1971 • 33 citations

Isolation of Lymphoid Cells with Active Surface Receptor Sites

1971 • 32 citations

Lord Rothschild in the Dock

1972 • 31 citations

Antigen-Binding Cells

1971 • 31 citations

A NEW METHOD FOR THE ENUMERATION OF ANTIGEN-REACTIVE CELLS RESPONSIVE TO A PURIFIED PROTEIN ANTIGEN

1969 • 31 citations

ANTIGEN-BINDING LYMPHOCYTES IN HUMAN FETAL THYMUS

1970 • 31 citations

Detection and Enumeration of Antibody-Producing Cells by Specific Adherence of Antigen-Coated Bentonite Particles

1966 • 30 citations

Specific Inhibition of an Antibody Response by Affinity Labelling

1969 • 30 citations

Specificity of Helper Function

1971 • 30 citations

INABILITY OF PERIPHERAL LYMPHOID CELLS OF AGAMMAGLOBULINAEMIC PATIENTS TO BIND RADIOIODINATED ALBUMINS

1969 • 28 citations

Antigen Binding Lymphocytes in Congenitally Athymic (Nude) Mice

1971 • 27 citations

Regulation of antibody response in vitro. Suppression of secondary response by anti-immunoglobulin heavy chains.

1971 • 27 citations

RECOGNITION OF ANTIGEN

1968 • 27 citations

Immunological Tolerance

2015 • 26 citations

Quantification of Antigen Specific T and B Lymphocytes in Mouse Spleens

1972 • 25 citations

Macrophage Cytophilic Antibody in Mice

1969 • 25 citations

The Role of the Carrier in Antibody Formation

1969 • 25 citations

Development of Restrictions in the Expression of Immunoglobulin Specificities by Lymphoid Cells

1970 • 24 citations

Antigen‐Binding Cells in Immune and Tolerant Animals

1972 • 24 citations

Differentiation and Immunology

1968 • 24 citations

The Affinity of Radioiodinated BSA for Lymphoid Cells

1969 • 24 citations

Genetic analysis of mutants producing defective β-galactosidase which can be activated by specific antibodies

1970 • 24 citations

REGULATION OF THE IMMUNE SYSTEM BY SYNTHETIC POLYNUCLEOTIDES

1972 • 23 citations

Detection of Antigen-binding Cells by Combined Rosette Formation and Autoradiography

1971 • 23 citations

Immunogenicity of Glucagon: Determinants Responsible for Antibody Binding and Lymphocyte Stimulation

1971 • 23 citations

Recognition of antigen by cells

1966 • 22 citations

Demonstration of Specific Antibodies on Human Circulating Lymphocytes by a New Technique

1967 • 21 citations

A study of the ontogeny of specific immune responsiveness amongst circulating leucocytes in the chicken.

1969 • 21 citations

Regulation of Antibody Response in Vitro

1971 • 21 citations

Selective inhibition of the secondary response of primed cells by incubation with hapten.

1968 • 20 citations

Passive sensitization of tissue cells. 1. Passive sensitization of macrophages by guinea-pig cytophilic antibody.

1965 • 19 citations

Antigen binding cells. II. Effect of highly radioactive antigen on the immunologic function of bone marrow cells.

1971 • 18 citations

The expression of immunoglobulin determinants on the surface of antigen‐binding lymphoid cells in mice. II. Allotypes of the lg‐1 locus

1971 • 18 citations

Affinity of radioiodinated bovine serum albumin for lymphoid cells. Binding of I-125-BSA to lymphoid cells of immune mice.

1969 • 17 citations

Affinity of antigen for white cells and its relation to the induction of antibody formation.

1968 • 16 citations

Altered Antigen Binding by Immunocompetent Cells as a Reflexion of Immunological History

1971 • 16 citations

Macrophage Cytophilic Antibody in Mice

1970 • 14 citations

Immunochemical studies on the poly-gamma-D-glutamyl capsule of Bacillus anthracis. VI. The in vivo fate and distribution to immunized rabbits of the polypeptide in immunogenic and nonimmunogenic forms.

1969 • 13 citations

Antibody-like Receptors on Immunocompetent Cells

1971 • 13 citations

Antigen binding and the immune response. I. The early primary response to a protein antigen.

1970 • 13 citations

Conserving Species

1972 • 11 citations

Antigen Binding Cells

1971 • 11 citations

Immunochemical studies on the poly-gamma-D-glutamyl capsule of Bacillus anthracis. V. The in vivo fate and distribution in rabbits of the polypeptide in immunogenic and nonimmunogenic forms.

1969 • 10 citations

Specific Detection of Antigen-Binding Cells by Localized Growth of Bacteria

1971 • 7 citations

Antigen Binding and the Immune Response

1970 • 7 citations

Affinity of antigen for white cells and its relation to the induction of antibody formation

1968 • 6 citations

Antigen Binding and the Immune Response II. The Large Number of Antigen-Binding Cells in Primed Animals

1970 • 6 citations

Immunologic competence of lymphoid cells in young amphibian larvae.

1970 • 5 citations

Thymus dependence of the antibody response to Maia squinado haemocyanin in mice.

1972 • 5 citations

Antigen-Binding Receptors on Lymphoid Cells. Nature and Specificity of Receptors on Various Types of Immunocompetent Cells

1971 • 4 citations

The Spectrum of Thymus Dependency

1971 • 3 citations

The Uptake of Antigens and Non-Antigenic Markers by Mouse Spleen and Peritoneal Cells

1971 • 2 citations

Deleted Work

1955 • 0 citations