Human neutrophil dysfunction with giant granules and defective activation of the respiratory burst

THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE

1966 • 6,585 citations

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Radioimmunoassay for Cyclic Nucleotides

1972 • 2,057 citations

The measurement of lysozyme activity and the ultra-violet inactivation of lysozyme

1952 • 1,118 citations

The microestimation of succinate and the extinction coefficient of cytochrome c

1959 • 751 citations

A Mechanism for the Production of Ethylene from Methional

1970 • 668 citations

Long-term culture of human bone marrow cells.

1980 • 624 citations

Superoxide generation by digitonin-stimulated guinea pig granulocytes. A basis for a continuous assay for monitoring superoxide production and for the study of the activation of the generating system.

1978 • 428 citations

Abnormal Bactericidal, Metabolic, and Lysosomal Functions of Chediak-Higashi Syndrome Leukocytes

1972 • 372 citations

Functional changes in human leukemic cell line HL-60. A model for myeloid differentiation

1979 • 302 citations

Correction of Leukocyte Function in Chediak-Higashi Syndrome by Ascorbate

1976 • 286 citations

Neutrophil Actin Dysfunction and Abnormal Neutrophil Behavior

1974 • 266 citations

Evidence for hydroxyl radical production by human neutrophils.

1977 • 257 citations

The distributions of some granule-associated enzymes in guinea-pig polymorphonuclear leucocytes

1970 • 249 citations

Myeloperoxidase Deficiency

1981 • 246 citations

Activity and activation of the granulocyte superoxide-generating system

1980 • 199 citations

CHRONIC GRANULOMATOUS DISEASE: CORRELATION BETWEEN PATHOGENESIS AND CLINICAL FINDINGS

1971 • 185 citations

Prenatal Diagnosis of Chronic Granulomatous Disease

1979 • 153 citations

The Chediak-Higashi Syndrome: Studies of Host Defenses

1972 • 146 citations

Phagocytosis in Chronic Granulomatous Disease and the Chediak–Higashi Syndrome

1972 • 141 citations

Receptor-mediated regulation of superoxide production in human neutrophils stimulated by phorbol myristate acetate.

1981 • 121 citations

A Variant of Chronic Granulomatous Disease: Deficient Oxidative Metabolism Due to a Low-Affinity NADPH Oxidase

1981 • 106 citations

Respiratory burst enzyme in human neutrophils. Evidence for multiple mechanisms of activation.

1981 • 104 citations

Immunocytochemical localization of myeloperoxidase, lactoferrin, lysozyme and neutral proteases in human monocytes and neutrophilic granulocytes.

1978 • 103 citations

Immunocytochemical Identification of Azurophilic and Specific Granule Markers in the Giant Granules of Chediak-Higashi Neutrophils

1978 • 103 citations

Spin label study of erythrocyte membrane fluidity in myotonic and Duchenne muscular dystrophy and congenital myotonia

1976 • 94 citations

Defective Granulocyte Regulation in the Chediak–Higashi Syndrome

1968 • 93 citations

Electron spin resonance study of membrane protein alterations in erythrocytes in Huntington's disease

1977 • 93 citations

Oxidative Damage to Neutrophils in Glutathione Synthetase Deficiency

1979 • 91 citations

Defective Initiation of Oxidative Metabolism in Polymorphonuclear Leukocytes

1979 • 89 citations

Efficacy of ascorbic acid in Chediak-Higashi syndrome (CHS): studies in humans and mice

1979 • 84 citations

Ultrastructural aspects of neutrophil granulocyte development in humans.

1970 • 74 citations

Improvement of Chediak-Higashi leukocyte function by cyclic guanosine monophosphate

1977 • 72 citations

Membrane Fluidity in Human and Mouse Chediak-Higashi Leukocytes

1979 • 66 citations

Human granulocytes generated in continuous bone marrow culture are physiologically normal

1981 • 64 citations

Effect of ascorbate on abnormal neutrophil, platelet and lymphocytic function in a patient with the Chediak-Higashi syndrome

1981 • 64 citations

The Chédiak-Higashi syndrome; the nature of the giant neutrophil granules and their interactions with cytoplasm and foreign particulates. I. Progressive enlargement of the massive inclusions in mature neutrophils. II. Manifestations of cytoplasmic injury and sequestration. III. Interactions between giant organelles and foreign particulates.

1980 • 61 citations

Immunocytochemical distinction between primary and secondary granule formation in developing human neutrophils: correlations with Romanowsky stains

1979 • 49 citations

Fluidity properties and liquid composition of erythrocyte membranes in Chediak-Higashi syndrome.

1981 • 48 citations

Evidence for production of oxidizing radicals by the particulate O-2- forming system from human neutrophils

1979 • 37 citations

Impaired granulocyte superoxide production and prolongation of the respiratory burst due to a low-affinity NADPH-dependent oxidase

1983 • 34 citations

Fine Structural Studies of Leukocytes from Patients and Heterozygotes with the Chediak-Higashi Syndrome

1969 • 29 citations

Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line.

1980 • 27 citations

Corticosteroid Dependence of Continuous Hemopoiesis In Vitro with Murine or Human Bone Marrow

1981 • 9 citations

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