Steroid hormone receptors in the regulation of differentiation. A review.

Solenoidal model for superstructure in chromatin.

1976 • 1,223 citations

A two-step mechanism for the interaction of estradiol with rat uterus.

1968 • 1,013 citations

Female Steroid Hormones and Target Cell Nuclei

1974 • 946 citations

Electron microscopic and biochemical evidence that chromatin structure is a repeating unit

1975 • 860 citations

Estrogen-Receptor Interaction

1973 • 746 citations

Steroid Receptors: Elements for Modulation of Eukaryotic Transcription

1976 • 688 citations

Membrane Receptors

1974 • 636 citations

Hormone Receptors: Studies on the Interaction of Estrogen with the Uterus

1968 • 537 citations

Selective Retention of Dihydrotestosterone by Prostatic Nuclei

1968 • 532 citations

Nonhistone Chromosomal Proteins and Gene Regulation

1974 • 439 citations

Isolation of nuclear pore complexes in association with a lamina.

1975 • 367 citations

REPRESSED AND ACTIVE CHROMATIN ISOLATED FROM INTERPHASE LYMPHOCYTES

1963 • 345 citations

Steroid Hormone Receptors

1976 • 345 citations

Histones H2a, H2b, H3, and H4 form a tetrameric complex in solutions of high salt

1975 • 334 citations

Estrogen-Induced Uterine Responses and Growth: Relationship to Receptor Estrogen Binding by Uterine Nuclei1¹

1975 • 321 citations

The subunit structure of the eukaryotic chromosome

1975 • 314 citations

Proteins associated with heterogeneous nuclear RNA in eukaryotic cells

1974 • 297 citations

Mechanism of Action of the Sex Steroid Hormones

1976 • 288 citations

Estrogen Receptors in the Rat Uterus

1969 • 282 citations

Progesterone antagonism of the oestrogen receptor and oestrogen-induced uterine growth

1975 • 273 citations

Hormonal Effects on Cell Proliferation in Rat Prostate

1976 • 264 citations

The Effect of Trypsin on Nuclease-resistant Chromatin Fragments

1974 • 234 citations

A receptor molecule for estrogens: studies using a cell-free system.

1967 • 229 citations

Progesterone Binding in the Mouse and Rat Uterus1

1972 • 224 citations

Full length and discrete partial reverse transcripts of globin and chorion mRNAs

1975 • 223 citations

Preparation and preliminary characterization of purified ovalbumin messenger RNA from the hen oviduct

1975 • 222 citations

Control of estrogen binding protein concentration under basal conditions and after estrogen administration

1971 • 216 citations

A model for particulate structure in chromatin

1974 • 214 citations

Mechanism of action of steroid hormones

1975 • 211 citations

Specific Sites of Interaction Between Histones and DNA in Chromatin

1974 • 204 citations

Glucocorticoid-Binding Proteins in Human Acute Lymphoblastic Leukemic Blast Cells

1973 • 192 citations

Cellular Receptors and Mechanisms of Action of Steroid Hormones

1975 • 192 citations

Specific progesterone receptors in human breast cancer

1975 • 188 citations

Progesterone-binding Components of Chick Oviduct

1972 • 178 citations

Equilibrium binding of estradiol by uterine cell suspensions and whole uteri in vitro

1974 • 169 citations

STUDIES WITH TRITIUM-LABELLED HEXŒSTROL IN ADVANCED BREAST CANCER

1961 • 167 citations

Receptors from Glucocorticoid-Sensitive Lymphoma Cells and Two Classes of Insensitive Clones: Physical and DNA-Binding Properties

1974 • 166 citations

SELECTION OF BREAST-CANCER PATIENTS FOR ADRENALECTOMY OR HYPOPHYSECTOMY BY DETERMINATION OF URINARY 17-HYDROXYCORTICOSTEROIDS AND ÆTIOCHOLANOLONE

1960 • 165 citations

Regulation of casein messenger RNA during the development of the rat mammary gland

1975 • 162 citations

Studies on Deoxyribonucleoprotein Structure

1971 • 156 citations

Estrogen-binding proteins of calf uterus. Partial purification and preliminary characterization of two cytoplasmic proteins

1971 • 155 citations

Progesterone-binding Components of Chick Oviduct

1971 • 149 citations

Some properties of a nuclear binding site of estradiol

1967 • 145 citations

Further evidence of transcriptional and translational control of histone messenger RNA during the HeLa S3 cycle

1975 • 145 citations

On the Specificity of the Binding of the Estradiol Receptor Protein to Deoxyribonucleic Acid

1974 • 144 citations

Reduced Estriol Excretion in Patients With Breast Cancer Prior to Endocrine Therapy

1966 • 144 citations

The interaction of estradiol-receptor protein with the genome: an argument for the existence of undetected specific sites

1975 • 144 citations

The use of protamine to study [6,7-3H]-oestradiol-17β binding in rat uterus

1970 • 132 citations

Progesterone “Receptor” in Rabbit Uterus.

1973 • 127 citations

The metabolism of histone fractions

1968 • 125 citations

Organisation of subunits in chromatin

1976 • 123 citations

SYNTHESIS AND INDUCTION OF TYROSINE AMINOTRANSFERASE IN SYNCHRONIZED HEPATOMA CELLS IN CULTURE

1969 • 122 citations

Peptide Hormones

1974 • 121 citations

Studies on estrogen entry into uterine cells and on estradiol-receptor complex attachment to the nucleus — Is the entry of estrogen into uterine cells a protein-mediated process?

1973 • 118 citations

ROLE OF CHROMATIN IN ESTROGEN ACTION IN THE UTERUS, II. HORMONE-INDUCED SYNTHESIS OF NONHISTONE ACIDIC PROTEINS WHICH RESTORE HISTONE-INHIBITED DNA-DEPENDENT RNA SYNTHESIS

1969 • 117 citations

Oestradiol Receptors in Carcinoma and Benign Disease of the Breast: An In Vitro Assay

1971 • 116 citations

Unstable nuclear RNA synthesis following estrogen stimulation

1970 • 113 citations

A method for determination of the in situ distribution of chromosomal proteins.

1976 • 112 citations

Characterization and Comparison of Receptors for 17β-Estradiol and Progesterone in Human Proliferative Endometrium and Endometrial Carcinoma

1975 • 110 citations

Medroxyprogesterone Acetate (Provera) in the Treatment of Metastatic Renal Cancer

1971 • 106 citations

Electron microscopy of chromatin subunit particles

1974 • 105 citations

Characterization of the 4 S and 5 S Forms of the Estradiol Receptor Protein and Their Interaction with Deoxyribonucleic Acid

1974 • 103 citations

Localization of the Reduced Nicotinamide Adenine Dinucleotide Phosphate: Δ4-3-Ketosteroid 5α-Oxidoreductase in the Nuclear Membrane of the Rat Ventral Prostate

1972 • 103 citations

Visualization of chromatin substructure: upsilon bodies.

1975 • 101 citations

Estrone Interaction with the Rat Uterus: In Vitro Response and Nuclear Uptake1

1973 • 99 citations

ŒSTROGEN PROFILES OF ASIAN AND NORTH AMERICAN WOMEN

1971 • 96 citations

Elevated Nonprotein-Bound Cortisol (NPC) in Pregnancy, During Estrogen Administration and in Carcinoma of the Prostate¹

1969 • 96 citations

Histone-histone associations within chromatin. Crosslinking studies using tetranitromethane

1975 • 94 citations

Changes in the concentration of high-affinity oestradiol receptors in rat uterine supernatant preparations during the oestrous cycle, pseudopregnancy, pregnancy, maturation and after ovariectomy

1970 • 93 citations

Reversible disaggregation of the cytosol-estrogen binding protein of uterine cytosol.

1968 • 92 citations

Histone-histone propinquity by aldehyde fixation of chromatin.

1975 • 91 citations

Early estrogen action: concomitant stimulations within two minutes of nuclear RNA synthesis and uptake of RNA precursor by the uterus.

1966 • 88 citations

The Role of Estrophilin in Estrogen Action

1975 • 84 citations

Hormonal Regulation of Ovalbumin Synthesis in Chick Oviduct

1973 • 80 citations

Concentration of Unconjugated Estrogens, Androgens and Gestagens in Ovarian and Peripheral Venous Plasma of Women: The Normal Menstrual Cycle¹

1971 • 80 citations

The binding of estradiol-17beta to human breast cancers and other tissues in vitro.

1970 • 77 citations

Histone-histone interactions within chromatin. Crosslinking studies using ultraviolet light

1976 • 75 citations

Estrophilic binding sites of the uterus. Relation to uptake and retention of estradiol in vitro

1973 • 75 citations

The properties of a nuclear acidic protein fraction that binds [6,7−3H]oestradiol-17β

1969 • 75 citations

Nonhistone Chromosomal Proteins in Synchronized HeLa Cells

1972 • 74 citations

An in vitro system for the binding of estradiol to rat uterine nuclei

1967 • 73 citations

Treatment of Prostatic Carcinoma with Various Types of Estrogen Derivatives

1976 • 70 citations

A model for curriculum evaluation

1972 • 69 citations

Transcription in vitro of immunoglobulin kappa light chain genes in isolated mouse myeloma nuclei and chromatin.

1976 • 69 citations

Nucleas action on chromatin: evidence for discrete, repeated nucleoprotein units along chromatin fibrils.

1975 • 66 citations

Purification of the sex steroid binding protein from human serum

1975 • 66 citations

Chromatin Fragments Resembling ν Bodies

1975 • 63 citations

Specific estrogen receptors in the lactating mammary gland of the rat

1973 • 62 citations

Biosynthesis and transformation of microsomal and cytosol estradiol receptors

1975 • 61 citations

Chromosomal proteins regulate steroid binding to chromatin

1976 • 61 citations

Affinity partitioning of steroid‐binding proteins. The use of polyethylene oxide‐bound estradiol for purifying Δ_5→43‐oxosteroid isomerase

1976 • 59 citations

Hydroxyprogesterone caproate therapy in advanced endometrial cancer

1971 • 59 citations

Endocrine Therapy of Breast Cancer

1975 • 55 citations

Progestogen treatment of recurrent endometrial carcinoma

1971 • 53 citations

Binding of estradiol-17-beta to human cancer tissue of the female genital tract.

1971 • 52 citations

Hormonal therapy in advanced renal cell carcinoma

1971 • 52 citations

In vitro binding of progesterone by the human endometrium during the menstrual cycle and by hyperplastic, atrophic, and carcinomatous endometrium

1971 • 50 citations

Glucocorticoid Binding Proteins in Human Leukaemic Lymphoblasts

1973 • 50 citations

Dissociation and reconstitution of chromatin without appreciable degradation of the proteins

1975 • 49 citations

INCORPORATION OF GLYCINE-2-C14 INTO PROTEIN BY SURVIVING UTERI FROM α-ESTRADIOL-TREATED RATS

1953 • 49 citations

Quaternary structure of chromatin.

1975 • 48 citations

Tissue-specific chromosomal non-histone protein interactions with DNA.

1976 • 46 citations

Effects of estrogen and progesterone on transcription, chromatin and ovalbumin gene expression in the chick oviduct

1976 • 46 citations

Interaction of cortisol with serum albumins

1965 • 45 citations

Some aspects of the mechanism of action of steroid hormones

1975 • 45 citations

Hypophysectomy and Adrenalectomy for Disseminated Prostatic Carcinoma

1971 • 43 citations

Localization of chromatin proteins within DNA grooves by methylation of chromatin with dimethyl sulphate

1974 • 42 citations

Accessible DNA in Chromatin

1974 • 40 citations

A model for chromarin sub-structure incorporating symmetry considerations of histone oligomers

1975 • 36 citations

Impaired Ventral Prostate Affinity for Testosterone in Hypophysectomized Rats

1965 • 36 citations

Bilateral adrenalectomy in metastatic mammary cancer:An analysis of sixty-four cases

1969 • 35 citations

Effects of high hoses of estrogen on prolactin-binding activity and growth of carcinogen-induced mammary cancers in rats.

1976 • 30 citations

OESTROGEN RECEPTORS IN HUMAN UTERINE TISSUE

1971 • 30 citations

Nuclear rceptor-estrogen complex: In vivo and in vitro binding of estradiol and estriol as influenced by serum albumin

1974 • 29 citations

The Use of Mercurated Nucleoside Triphosphate as a Probe in Transcription Studies in vitro

1976 • 28 citations

Receptor transformation, the key to estrogen action

1975 • 26 citations

Pharmacoclinical study of oral estramustine phosphate (estracyt) in advanced carcinoma of the prostate

1975 • 25 citations

A double coil chromatin sub-unit model

1976 • 24 citations

Conformational studies of steroids: Correlations with biological data

1975 • 23 citations

Steroid Hormone Receptors: A Survey

1976 • 23 citations

The proteins of polytene chromosomes of Drosophila hydei

1975 • 23 citations

Chemotherapy of Prostatic Cancer

1975 • 21 citations

Estrogen induction of ovalbumin mRNA: Evidence for transcription control

1975 • 21 citations

The possibility of predicting the response of patients with early breast cancer to subsequent endocrine ablation.

1965 • 16 citations

Steroid‐protein interactions. Purification of progesterone‐binding globulin by affinity chromatography

1976 • 16 citations

Androgen Binding and Metabolism in the Human Prostate

1976 • 16 citations

Androgen Metabolism in Patients with Benign Prostatic Hypertrophy

1976 • 14 citations

Metabolic Activities of Histones in Rat Liver and Spleen

1975 • 12 citations

The Nonsurgical Treatment of Prostatic Carcinoma

1976 • 10 citations

Relation of estrogen to prolactin secretion in animals and man.

1975 • 10 citations

Potential Test Systems for Chemotherapeutic Agents against Prostatic Cancer

1976 • 8 citations

Prolactin and the ventral prostate gland in juvenile rats

1969 • 8 citations

The determination of RNA homogeneity by molecular hybridization

1974 • 8 citations

Drosophila chromatin: an immunological study

1975 • 7 citations

Electron microscope observations of the organisation of chromatin fibers in isolated nuclei of rat liver

1974 • 7 citations

Hormonal therapy in metastatic hypernephroma

1974 • 7 citations

Effects of Hormone-Cytostatic Complexes on the Rat Ventral Prostate In Vivo and In Vitro

1976 • 6 citations

Model building studies on the structure of deoxyribonucleohistone

1970 • 4 citations

Management of Reactivated Prostatic Cancer

1976 • 2 citations