Interleukin-8 primes human neutrophils for enhanced superoxide anion production.

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

1989 • 1,060 citations

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

1987 • 983 citations

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

1991 • 961 citations

Regulation of Rransendothelial Neutrophil Migration by Endogenous Interleukin-8

1991 • 813 citations

The extinction coefficient of cytochrome c

1962 • 693 citations

Lipid activation of protein kinase C.

1991 • 566 citations

Red blood cells are a sink for interleukin 8, a leukocyte chemotaxin.

1991 • 454 citations

Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation.

1990 • 435 citations

Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components.

1991 • 346 citations

Human GM-CSF primes neutrophils for enhanced oxidative metabolism in response to the major physiological chemoattractants

1987 • 333 citations

Enhancement of neutrophil superoxide production by preincubation with recombinant human tumor necrosis factor.

1987 • 292 citations

Detection of interleukin 8 biological activity in synovial fluids from patients with rheumatoid arthritis and production of interleukin 8 mRNA by isolated synovial cells

1990 • 274 citations

Quantitative aspects of the production of superoxide radicals by phagocytizing human granulocytes.

1975 • 265 citations

Enhanced production of neutrophil-activating peptide-1/interleukin-8 in rheumatoid arthritis.

1991 • 256 citations

Phosphorylation of neutrophil 47-kDa cytosolic oxidase factor. Translocation to membrane is associated with distinct phosphorylation events.

1990 • 248 citations

Interleukin-8 induces neutrophil transendothelial migration.

1991 • 238 citations

Functional activation of human neutrophils by recombinant monocyte-derived neutrophil chemotactic factor/IL-8.

1990 • 229 citations

Biosynthetic human GM-CSF modulates the number and affinity of neutrophil f-Met-Leu-Phe receptors.

1986 • 218 citations

The role of cytokines in the pathogenesis of inflammatory eye disease

1992 • 218 citations

Monocyte‐derived neutrophil chemotactic factor/interleukin‐8 is a potential mediator of crystal‐induced inflammation

1991 • 195 citations

Using quin2 in cell suspensions

1985 • 180 citations

Recombinant human tumor necrosis factor-alpha. Regulation of N-formylmethionylleucylphenylalanine receptor affinity and function on human neutrophils.

1988 • 162 citations

Stimulation and priming of human neutrophils by interleukin-8: cooperation with tumor necrosis factor and colony-stimulating factors

1991 • 153 citations

Neutrophil Recruitment by Intradermally Injected Neutrophil Attractant/Activation Protein-1

1991 • 125 citations

[Ca2+]i Changes and Respiratory Burst in Human Neutrophils and Monocytes Induced by NAP-1/Interleukin-8, NAP-2, and gro/MGSA

1991 • 123 citations

Inhibition of Rap1A Binding to Cytochrome b ₅₅₈ of NADPH Oxidase by Phosphorylation of Rap1A

1991 • 120 citations

Protein kinase C-dependent and -independent activation of the NADPH oxidase of human neutrophils.

1991 • 120 citations

Presence of NAP‐1/IL‐8 in Synovial Fluids Indicates a Possible Pathogenic Role in Rheumatoid Arthritis

1991 • 114 citations

Priming of the human neutrophil respiratory burst by granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha involves regulation at a post-cell surface receptor level. Enhancement of the effect of agents which directly activate G proteins.

1990 • 111 citations

Activation of NADPH oxidase in human neutrophils. Synergism between fMLP and the neutrophil products PAF and LTB4

1985 • 110 citations

Tumor necrosis factor as an activator of human granulocytes. Potentiation of the metabolisms triggered by the Ca2+-mobilizing agonists.

1989 • 107 citations

Human granulocyte chemotactic peptide (IL-8) as a specific neutrophil degranulator: comparison with other monokines.

1989 • 99 citations

Inhibition of superoxide and nitric oxide release and protection from reoxygenation injury by ebselen in rat kupffer cells

1992 • 98 citations

Granulocyte-macrophage colony-stimulating factor modulates the excitation-response coupling sequence in human neutrophils.

1988 • 82 citations

Inflammatory Properties of Neutrophil-Activating Protein-1/Interleukin 8 (NAP-1/IL-8) in Human Skin: A Light- and Electronmicroscopic Study

1991 • 82 citations

Recombinant human monocyte IL-8 primes NADPH-oxidase and phospholipase A2 activation in human neutrophils.

1992 • 80 citations

Human neutrophil activating peptide/interleukin 8 acts as an autoantigen in rheumatoid arthritis.

1992 • 67 citations

Tumor necrosis factor-alpha priming of phospholipase A2 activation in human neutrophils. An alternative mechanism of priming.

1991 • 66 citations

Tumor necrosis factor-alpha regulates expression of receptors for formyl-methionyl-leucyl-phenylalanine, leukotriene B4, and platelet-activating factor. Dissociation from priming in human polymorphonuclear neutrophils.

1991 • 62 citations

Synergism between phorbol ester and A23187 in Superoxide production by neutrophils

1984 • 50 citations

Delineation of the phagocyte NADPH oxidase through studies of chronic granulomatous diseases of childhood

1992 • 25 citations

Stimulation and priming of protein kinase C translocation by a Ca2+ transient-independent mechanism. Studies in human neutrophils challenged with platelet-activating factor and other receptor agonists.

1990 • 24 citations

Calcium ionophore A23187 enhances human neutrophil superoxide release, stimulated by phorbol dibutyrate, by converting phorbol ester receptors from a low‐ to high‐affinity state

1987 • 19 citations