The Interferons: Their Properties and Clinical Role — An Overview

Peptide Regulatory Factors

1989 • 498 citations

Treatment of Pulmonary Hemangiomatosis with Recombinant Interferon Alfa-2a

1989 • 444 citations

Combination therapy with interleukin-2 and alpha-interferon for the treatment of patients with advanced cancer.

1989 • 383 citations

Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: a review.

1990 • 351 citations

Fluorouracil and recombinant alfa-2a-interferon: an active regimen against advanced colorectal carcinoma.

1989 • 336 citations

Home therapy with recombinant interleukin-2 and interferon-$alpha;2b in advanced human malignancies

1990 • 296 citations

Neuropsychiatric Manifestations of Human Leukocyte Interferon Therapy in Patients With Cancer

1984 • 244 citations

Interferon alfa-2a in the treatment of cutaneous T cell lymphoma

1989 • 226 citations

Intraperitoneal recombinant alpha-interferon for "salvage" immunotherapy in stage III epithelial ovarian cancer: a Gynecologic Oncology Group Study.

1985 • 181 citations

Therapy of metastatic carcinoid tumor and the malignant carcinoid syndrome with recombinant leukocyte A interferon.

1989 • 168 citations

Intralesional interferon-alpha therapy in advanced malignant melanoma

1988 • 153 citations

INTERFERONS

1989 • 153 citations

HOSPITAL LIBRARIANS

1974 • 146 citations

Clinical update on the role of fluorouracil and recombinant interferon alfa-2a in the treatment of colorectal carcinoma.

1990 • 134 citations

Current therapy for malignant melanoma.

1989 • 127 citations

MYOPATHIES: THE NEUROGENIC HYPOTHESIS?

1974 • 118 citations

An autoimmune aetiology for hypothyroidism following interferon therapy for breast cancer

1988 • 111 citations

LONG-TERM INTERFERON THERAPY FOR THROMBOCYTOSIS IN MYELOPROLIFERATIVE DISEASES

1989 • 105 citations

Incidence of response and long-term follow-up in patients with hairy cell leukemia treated with recombinant interferon alfa-2a [see comments]

1990 • 98 citations

Intrapleural Natural Beta Interferon in the Treatment of Malignant Pleural Effusions

1988 • 83 citations

Phase II trial of intermittent high-dose recombinant interferon alfa-2a in mycosis fungoides and the Sézary syndrome.

1990 • 81 citations

Recombinant alpha2 interferon-related cardiomyopathy

1988 • 79 citations

Therapeutic options in renal cell carcinoma.

1989 • 78 citations

Treatment of malignant carcinoid tumors: a randomized controlled study of streptozocin plus 5-FU and human leukocyte interferon

1989 • 73 citations

Therapy of chronic myelogenous leukemia: chemotherapy and interferons.

1988 • 61 citations

Alpha recombinant interferon in the treatment of mycosis fungoides (MF).

1987 • 55 citations

Positive interactions between interferon and chemotherapy due to direct tumor action rather than effects on host drug-metabolizing enzymes.

1984 • 53 citations

A phase II study of human rDNA alpha-2 interferon in patients with low grade non-Hodgkin's lymphoma

1986 • 49 citations

Interferon-related mental deterioration and behavioral changes in patients with renal cell carcinoma

1990 • 47 citations

Recombinant interferon-alpha therapy of Philadelphia chromosome-negative myeloproliferative disorders with thrombocytosis

1989 • 38 citations

Cytokines in cancer therapy

1989 • 38 citations

Prospective randomized trial of topical α-interferon (α-interferon gels) for the treatment of vulvar intraepithelial neoplasia III

1990 • 31 citations

Successful treatment of mycosis fungoides with the combination of etretinate and human recombinant interferon alfa-2a

1989 • 28 citations

Aerosol application of interferon-alpha in the treatment of bronchioloalveolar carcinoma

1990 • 28 citations

The regulation of beta-interferon gene expression.

1990 • 28 citations

Effect of inhaled natural interferon-alpha on diffuse bronchioalveolar carcinoma

1990 • 25 citations

Intravesical interferon treatment of superficial bladder cancer

1989 • 16 citations

Treatment of Superficial Bladder Tumors with Intravesical Recombinant Interferon Alpha-2a

1988 • 12 citations

A phase I trial of recombinant human gamma interferon (IFN-gamma 4A) in patients with advanced malignancy.

1988 • 12 citations

Therapeutic approaches including interferon to carcinoma in situ of the bladder.

1985 • 11 citations

Is there a role for interferon in the treatment of small cell lung cancer?

1989 • 8 citations

Interferon therapy of relapsed and refractory Hodgkin's disease: Cancer and Leukemia Group B Study 8652.

1990 • 7 citations

Interferon in the treatment of ovarian cancer.

1988 • 7 citations

Natural Alpha Interferon as Part of a Combined Treatment for Small Cell Lung Cancer

1987 • 5 citations

Alpha interferon in the treatment of chronic myelomonocytic leukemia.

1989 • 5 citations

Interferon Inhibition of Bombesin-Stimulated Mitogenesis in Swiss 3T3 Cells Occurs Without Blocking c-fosand c-mycExpression

1989 • 4 citations