Regulation of Tissue Plasminogen Activator Secretion from Human Endothelial Cells

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Mechanism of Plasminogen Activator and Factor VIII Increase after Vasoactive Drugs

1975 • 400 citations

Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells.

1984 • 330 citations

Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1.

1986 • 325 citations

Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol.

1983 • 292 citations

STUDIES ON ENHANCED FIBRINOLYTIC ACTIVITY IN MAN*

1959 • 285 citations

Glucocorticoid-modulated gene expression of tissue- and urinary-type plasminogen activator and plasminogen activator inhibitor 1 and 2.

1988 • 168 citations

Fibrin induces release of von Willebrand factor from endothelial cells.

1987 • 163 citations

Histamine-induced phosphoinositide metabolism in cultured human umbilical vein endothelial cells. Association with thromboxane and prostacyclin release

1987 • 74 citations

Stimulation and desensitization of tissue plasminogen activator release from human endothelial cells.

1988 • 73 citations

Induction of fibrinolytic activity in HeLa cells by phorbol myristate acetate. Tissue-type plasminogen activator antigen and mRNA augmentation require intermediate protein biosynthesis.

1985 • 73 citations

Regulation of tissue-type plasminogen activator activity and messenger RNA levels by gonadotropin-releasing hormone in cultured rat granulosa cells and cumulus-oocyte complexes.

1987 • 72 citations

Hormonal regulation of tissue plasminogen activator secretion and mRNA levels in rat granulosa cells.

1987 • 68 citations

Prostacyclin synthesis and deacylation of phospholipids in human endothelial cells: Comparison of thrombin, histamine and ionophore A23187

1985 • 66 citations

Phorbol esters and diacylglycerols amplify bradykinin-stimulated prostaglandin synthesis in Swiss 3T3 fibroblasts. Possible independence from protein kinase C.

1988 • 57 citations

Inhibition of phorbol ester-induced phenotypic differentiation of HL-60 cells by 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine, a protein kinase inhibitor.

1986 • 56 citations

Cyclic AMP-dependent and -independent effects on tissue-type plasminogen activator activity in osteogenic sarcoma cells; evidence from phosphodiesterase inhibition and parathyroid hormone antagonists

1986 • 44 citations

Effects of protein kinase inhibitor (1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H7) on protein kinase C activity and adrenergic stimulation of cAMP and cGMP in rat pinealocytes

1988 • 37 citations

Mechanism of the Stimulatory Effect of Phorbol 12-Myristate 13-Acetate on Cellular Production of Plasminogen Activator

1984 • 17 citations

Deleted Work

1955 • 0 citations