Studies on the proliferation and fate of oval cells in the liver of rats treated with 2-acetylaminofluorene and partial hepatectomy.

THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE

1966 • 6,585 citations

THE UNLABELED ANTIBODY ENZYME METHOD OF IMMUNOHISTOCHEMISTRY PREPARATION AND PROPERTIES OF SOLUBLE ANTIGEN-ANTIBODY COMPLEX (HORSERADISH PEROXIDASE-ANTIHORSERADISH PEROXIDASE) AND ITS USE IN IDENTIFICATION OF SPIROCHETES

1970 • 5,141 citations

HISTOCHEMICAL AND ULTRASTRUCTURAL DEMONSTRATION OF γ-GLUTAMYL TRANSPEPTIDASE ACTIVITY

1969 • 940 citations

Similarities in the sequence of early histological changes induced in the liver of the rat by ethionine, 2-acetylamino-fluorene, and 3'-methyl-4-dimethylaminoazobenzene.

1956 • 670 citations

The Sequential Analysis of Cancer Development

1980 • 613 citations

Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis.

1977 • 541 citations

Biochemical characterisation of stages of hepatocarcinogenesis after a single dose of diethylnitrosamine

1978 • 415 citations

Ethionine Carcinogenesis

1963 • 296 citations

Early histological and functional alterations of ethionine liver carcinogenesis in rats fed a choline-deficient diet.

1978 • 248 citations

Induction of resistant hepatocytes as a new principle for a possible short-term in vivo test for carcinogens.

1980 • 243 citations

Phenotypic diversity as an early property of putative preneoplastic hepatocyte populations in liver carcinogenesis.

1980 • 203 citations

Cellular analysis of liver carcinogenesis: the induction of large hyperplastic nodules in the liver with 2-fluorenylacetamide or ethionine and some aspects of their morphology and glycogen metabolism.

1967 • 202 citations

Gamma-glutamyltransferase in putative premalignant liver cell populations during hepatocarcinogenesis.

1978 • 195 citations

Role of cholangioles in restoration of the liver of the mouse after dietary injury

1958 • 185 citations

Kinetics of phenotypic maturation of remodeling of hyperplastic nodules during liver carcinogenesis.

1982 • 177 citations

An Evaluation of Cellular Lineages in the Pathogenesis of Experimental Hepatocellular Carcinoma

1982 • 176 citations

Progressive microscopic alterations in the livers of rats fed the hepatic carcinogens 3'-methyl-4-dimethylaminoazobenzene and 4'-fluoro-4-dimethylaminoazobenzene.

1952 • 168 citations

Electron microscopic studies of normal and proliferated bile ductules.

1961 • 166 citations

Quantitative histochemical and autoradiographic studies of hepatocarcinogenesis in rats fed 2-acetylaminofluorene followed by phenobarbital.

1978 • 157 citations

Ductular cell reaction in the liver in hepatic injury.

1957 • 134 citations

Morphologic identification by electron microscopy of "oval" cells in experimental hepatic degeneration.

1961 • 131 citations

Origin and fate of proliferated hepatic ductal cells in the rat: Electron microscopic and autoradiographic studies

1964 • 128 citations

Regional Differences in the Growth of Normal and Neoplastic Cells

1982 • 100 citations

Early appearance of embryonic -globulin in rat serum during carcinogenesis with 4-dimethylaminoazobenzene.

1971 • 98 citations

Significance of the so-called oval cell proliferation during azo-dye hepatocarcinogenesis.

1967 • 98 citations

Immunofluorescent study on alpha-fetoprotein-producing cells in the early stage of 3'-methyl-4-dimethylaminoazobenzene carcinogenesis.

1975 • 92 citations

Distribution of alpha-fetoprotein- and albumin-containing cells in the livers of Fischer rats fed four cycles of N-2-fluorenylacetamide.

1978 • 89 citations

Demonstration of glucose 6-phosphatase activity in the oval cells of rat liver and the significance of the oval cells in azo dye carcinogenesis.

1974 • 86 citations

Autoradiography of “oval cells” appearing rapidly in the livers of rats fed N-2-fluorenylacetamide in a choline devoid diet

1981 • 86 citations

Promotion of liver cancer development by brief exposure to dietary 2-acetylaminofluorene plus partial hepatectomy or carbon tetrachloride.

1983 • 86 citations

Localization of ALPHA₁‐fetoprotein and DNA‐synthesis in liver cell populations during experimental hepatocarcinogenesis in rats

1978 • 82 citations

The carcinogenic effect of aramite in rats.A study of hepatic nodules

1960 • 77 citations

Sequential analysis of hepatic carcinogenesis: a comparative study of the ultrastructure of preneoplastic, malignant, prenatal, postnatal, and regenerating liver.

1979 • 72 citations

A morphological and histochemical study of carcinogenesis of the liver in rats fed 3'-methyl-4-dimethylaminoazobenzene.

1973 • 68 citations

Effects of a choline-devoid diet on the emergence of gamma-glutamyltranspeptidase-positive foci in the liver of carcinogen-treated rats.

1979 • 63 citations

α‐fetoprotein and hepatocarcinogenesis in rats fed 3′‐methyl‐4‐(dimethylamino)azobenzene or n‐2‐fluorenylacetamide

1972 • 63 citations

The origin and fate of proliferated bile ductular cells

1964 • 62 citations

α‐FETOPROTEIN AND EARLY HISTOLOGICAL CHANGES OF HEPATIC TISSUE IN DAB‐HEPATOCARCINOGENESIS*

1975 • 55 citations

Immunohistochemical localization of prekeratin filaments in benign and malignant cells in effusions. Comparison with intermediate filament distribution by electron microscopy.

1982 • 52 citations

Immunohistochemical study of epoxide hydrolase during experimental liver carcinogenesis.

1981 • 46 citations

Electron microscopy of hyperplastic ductular cells in alpha-naphthyl isothiocyanateinduced cirrhosis.

1963 • 46 citations

CELL MODULATION IN LIVER PATHOLOGY

1959 • 44 citations

α‐Fetoprotein‐containing cells in the early stages of liver carcinogenesis induced by 3′‐methyl‐4‐dimethyl‐aminoazobenzene and 2‐acetylaminofluorene

1977 • 42 citations

Fluctuation of various cell populations and their characteristics during azo-dye carcinogenesis.

1972 • 35 citations

Some factors regulating the structural integrity of the intrahepatic bile ducts with special reference to primary carcinoma of the liver and vitamin A

1954 • 31 citations

Immunochemical localization of epoxide hydratase in rat liver: Effects of 2-acetylaminofluorene

1979 • 31 citations

Sequential analysis of hepatic carcinogenesis. Regeneration of liver after carbon tetrachloride-induced liver necrosis when hepatocyte proliferation is inhibited by 2-acetylaminofluorene.

1983 • 30 citations

Cell types involved in the expression of foetal aldolases during rat azo-dye hepatocarcinogenesis

1981 • 21 citations

Deoxyribonucleic acid turnover in a heterogeneous population. Life span of hepatic ductular cells.

1963 • 17 citations

Chemicals, evolution, and cancer development: Rous-Whipple Award Lecture.

1982 • 13 citations

Immunohistological studies on alpha1-fetoprotein and alpha1-acid glycoprotein during azo dye hepatocarcinogenesis in rats.

1976 • 10 citations