On the Origin of Pandemic Influenza Viruses

Ciba foundation symposium

1964 • 2,217 citations

Fundamental techniques in virology.

1969 • 1,768 citations

VIRAL AND RICKETTSIAL INFECTIONS OF MAN

1953 • 525 citations

PERSISTENT ANTIGENIC VARIATION OF INFLUENZA A VIRUSES AFTER INCOMPLETE NEUTRALIZATION IN OVO WITH HETEROLOGOUS IMMUNE SERUM

1950 • 485 citations

Viral and Rickettsial Infections of Man.

1966 • 438 citations

EPIDEMIOLOGIC AND IMMUNOLOGIC SIGNIFICANCE OF AGE DISTRIBUTION OF ANTIBODY TO ANTIGENIC VARIANTS OF INFLUENZA VIRUS

1953 • 390 citations

Influenza virus proteins

1970 • 341 citations

Morphology of the isolated hemagglutinin and neuraminidase subunits of influenza virus

1969 • 321 citations

Influenza virus structural and nonstructural proteins in infected cells and their plasma membranes

1971 • 319 citations

Genetic Recombination with Newcastle Disease Virus, Polioviruses, and Influenza

1962 • 270 citations

The structure of influenza virus

1970 • 247 citations

The polypeptide composition of influenza a viruses

1971 • 241 citations

The Biology of Large RNA Viruses

1971 • 221 citations

Functional significance of sialidase during influenza virus multiplication

1966 • 198 citations

Preparation and Properties of Antibody Directed Specifically Against the Neuraminidase of Influenza Virus

1967 • 197 citations

Lipids of plasma membranes of monkey and hamster kidney cells and of parainfluenza virions grown in these cells

1969 • 195 citations

Separation of two polypeptide chains from the hemagglutinin subunit of influenza virus

1971 • 175 citations

Hong Kong A-2 Influenza Virus Infection among Swine during a Human Epidemic in Taiwan

1970 • 162 citations

Polyacrylamide gel electrophoresis of influenza virus RNA

1968 • 157 citations

PRE-EPIDEMIC ANTIBODY AGAINST 1957 STRAIN OF ASIATIC INFLUENZA IN SERUM OF OLDER PEOPLE LIVING IN THE NETHERLANDS

1958 • 155 citations

The structure of influenza virus

1972 • 151 citations

The RNA of influenza virus.

1968 • 151 citations

INDEPENDENT VARIATION IN NATURE OF HEMAGGLUTININ AND NEURAMINIDASE ANTIGENS OF INFLUENZA VIRUS: DISTINCTIVENESS OF HEMAGGLUTININ ANTIGEN OF HONG KONG/68 VIRUS

1969 • 149 citations

Genetically stable reassortment of markers during mixed infection with avian tumor viruses

1971 • 138 citations

The structure of influenza viruses

1966 • 128 citations

An electron microscopic study of single-cycle infection of chick embryo fibroblasts by influenza virus

1969 • 125 citations

Genetic recombination among influenza viruses

1961 • 125 citations

Plasma membrane lipids and parainfluenza virus assembly

1970 • 124 citations

Temperature-sensitive mutants of influenza a virus: Isolation of mutants and preliminary observations on genetic recombination and complementation

1968 • 124 citations

A genetic map of poliovirus temperature-sensitive mutants

1968 • 124 citations

Studies on the origin of pandemic influenza

1972 • 116 citations

Lipids of influenza virus and their relation to those of the host cell

1961 • 115 citations

Distinct subunits of the ribonucleoprotein of influenza virus

1969 • 109 citations

Reactions of Antibodies with Surface Antigens of Influenza Virus

1968 • 109 citations

Correlated Studies of a Recombinant Influenza-Virus Vaccine. I. Derivation and Characterization of Virus and Vaccine

1971 • 105 citations

RNA-Dependent RNA Polymerase Activity Associated with Virions and Subviral Particles of Myxoviruses

1971 • 102 citations

THE NUCLEIC ACID CONTENT OF INFLUENZA VIRUS

1954 • 100 citations

Selection of antigenic mutants of influenza viruses. Isolation and peptide mapping of their hemagglutinating proteins

1968 • 97 citations

THE HONG KONG/68 INFLUENZA A2 VARIANT

1968 • 94 citations

EPIDEMIC INFLUENZA: A VIRUS DISEASE

1935 • 93 citations

The polypeptides of influenza virus

1971 • 93 citations

Antigenic hybrids of influenza a viruses with surface antigens to order

1970 • 92 citations

An electron microscopic study of the presence or absence of neuraminic acid in enveloped viruses

1970 • 91 citations

THE EXPERIMENTAL PRODUCTION OF COMBINATION FORMS OF VIRUS

1953 • 89 citations

Recombination of Influenza A Viruses of Human and Animal Origin

1968 • 88 citations

The “in vivo” production of “new” influenza a viruses

1971 • 87 citations

Studies on the origin of pandemic influenza

1972 • 87 citations

Transcription of the Influenza Ribonucleic Acid Genome by a Virion Polymerase I. Optimal Conditions for In Vitro Activity of the Ribonucleic Acid-Dependent Ribonucleic Acid Polymerase

1971 • 85 citations

The polypeptides of influenza virus

1970 • 84 citations

The multiplication of influenza virus

1961 • 79 citations

Studies on mixed infection with Newcastle disease virus

1959 • 77 citations

A Common Surface Antigen in Influenza Viruses from Human and Avian Sources

1968 • 76 citations

Transcription of the Influenza Ribonucleic Acid Genome by a Virion Polymerase III. Completeness of the Transcription Process

1972 • 74 citations

New virus-specific antigens in cells infected with influenza virus

1969 • 72 citations

5′-Terminus of Influenza Virus RNA

1971 • 67 citations

The single- and double-stranded RNA's and the proteins of incomplete influenza virus

1969 • 66 citations

Characterization of the Subunit Structure of the Ribonucleic Acid Genome of Influenza Virus

1971 • 66 citations

Proteins Specified by Influenza Virus in Infected Cells: Analysis by Polyacrylamide Gel Electrophoresis of Antigens Not Present in the Virus Particle

1969 • 65 citations

Genetic interaction between influenza A viruses of human and animal origin

1965 • 63 citations

RNA-dependent RNA polymerase activity of the influenza virus

1971 • 63 citations

Influenza Virus Polypeptides and Antigens--Summary of Influenza Workshop I

1972 • 62 citations

The RNAs of infective and incomplete influenza virions grown in MDBK and HeLa cells

1970 • 61 citations

Isolation of Temperature-sensitive Mutants and the Construction of a Preliminary Genetic Map for Influenza Virus

1970 • 61 citations

Antigenic variation in influenza virus. Biology and chemistry.

1971 • 56 citations

Some Properties of Influenza Virus Nucleocapsids

1969 • 55 citations

Structure of Influenza Virus

1956 • 55 citations

Antigenic Relationship between Influenza A Viruses of Human and Avian Origins

1967 • 54 citations

RELATION BETWEEN HONG KONG VIRUS AND FORMER HUMAN A2 ISOLATES AND THE A/EQUI2 VIRUS IN HUMAN SERA COLLECTED BEFORE 1957

1969 • 54 citations

Transcription of the Influenza Ribonucleic Acid Genome by a Virion Polymerase II. Nature of the In Vitro Polymerase Product

1971 • 54 citations

Isolation of influenza virus ribonucleoprotein from infected cells. Demonstration of the presence of negative-stranded RNA in viral RNP

1971 • 53 citations

Undisturbed release of influenza virus in the presence of univalent antineuraminidase antibodies

1971 • 52 citations

A Virus Made from Parts of the Genomes of Brome Mosaic and Cowpea Chlorotic Mottle Viruses

1972 • 52 citations

The polypeptides of influenza virus

1969 • 52 citations

Experimental Infection of Human Volunteers with Equine Influenza Virus

1965 • 52 citations

A Genetic Approach to Variation in Influenza Viruses: 4. Recombination of Characters Between the Influenza Virus A Strain NWS and Strains of Different Serological Subtypes

1951 • 49 citations

Origin of Lipids in Influenza Virus

1962 • 49 citations

Experimental infection in man and horses with influenza A viruses.

1969 • 48 citations

Antigenic Composition of Recombinant Virus Strains Produced from Human and Avian Influenza A Viruses

1969 • 47 citations

Infection with A2 Hong Kong influenza virus in domestic cats.

1970 • 46 citations

Estimations of the Molecular Weight of the Influenza Virus Genome

1971 • 46 citations

The Biology of Large RNA Viruses.

1971 • 46 citations

Studies of Antibodies to 1956 and 1963 Equine Influenza Viruses in Horses and Man

1965 • 44 citations

Immunological relationships between the neuraminidases of human and animal influenza viruses.

1969 • 43 citations

Serological epidemiological studies with influenza A viruses

1965 • 43 citations

Myxovirus Ribonucleic Acids

1970 • 42 citations

The polypeptides of influenza virus

1970 • 42 citations

Studies on the content of antibodies for equine influenza viruses in human sera.

1966 • 42 citations

Serological survey in animals for type A influenza in relation to the 1957 pandemic.

1959 • 40 citations

The multiplication of influenza virus

1961 • 40 citations

THE CLINICAL EPIDEMIOLOGY OF ASIAN INFLUENZA

1958 • 39 citations

The characterization of subviral particles derived from influenza virus

1971 • 39 citations

Relationship of envelope antigens of animal influenza viruses to human A2 influenza strains isolated in the years 1957-68.

1969 • 38 citations

Studies on Antigenic Variations of the Haemagglutinin and Neuraminidase of Swine Influenza Virus Isolates

1970 • 35 citations

Hong Kong influenza infection in swine: experimental and field observations.

1972 • 32 citations

Viruses with segmented ribonucleic acid genomes: multiplication of influenza versus reovirus

1971 • 30 citations

Neuraminidase in Avian Influenza A Virus antigenically related to that of Human A0 and A1 Subtypes

1969 • 30 citations

Genetic studies of influenza viruses

1966 • 30 citations

The induction of broadened (multitypic) immunity with doubly antigenic influenza virus recombinants.

1965 • 30 citations

The experimental production of combination forms of virus

1955 • 30 citations

New criteria for the selection of influenza vaccine strains.

1969 • 28 citations

Influenza (A2/Hong Kong/68) in the Baboon (Papio sp.)

1969 • 28 citations

Internal structure of influenza virus

1965 • 27 citations

Properties of the Hong Kong influenza virus. Antigenic relationship of the Hong Kong virus haemagglutinin to that of other human influenza A viruses.

1969 • 27 citations

THE INFLUENZAS OF SWINE AND MAN1

1936 • 27 citations

Evolution and Hierarchy of Influenza Viruses

1970 • 27 citations

An Epizootic of A2/Hong Kong/68 Influenza in Gibbons

1971 • 26 citations

Immunological interrelationships of Hong Kong, Asian and equi-2 influenza viruses in man.

1969 • 26 citations

Communications. Antigenic relationship between the equine and the Hong Kong human variant of influenza type A2 virus.

1969 • 26 citations

FURTHER OBSERVATIONS ON THE SIGNIFICANCE OF A/EQUINE-2/63 ANTIBODIES IN MAN

1967 • 25 citations

ANTIGENIC VARIANTS OF INFLUENZA A VIRUS (PR8 STRAIN)

1958 • 25 citations

HONG KONG INFLUENZA IMMUNOLOGIC RECAPITULATION1

1969 • 25 citations

Distribution and Significance of Asian and Other Influenza Antibodies in the Human Population

1958 • 24 citations

Influenza in animals.

1968 • 24 citations

Replication and functions of myxovirus ribonucleic acids.

1970 • 23 citations

Electron Microscope Study of Ribonucleic Acid of Myxoviruses

1971 • 22 citations

Antibodies to influenza viruses (including the human A2-Asian-57 strain) in sera from Australian shearwaters (Puffinus pacificus).

1970 • 18 citations

Antibody Response obtained by Vaccination with the Influenza A/Equi 2 Virus in Man

1968 • 18 citations

On the Nature of the Influenza Virus Genome

1970 • 17 citations

Variation in laboratory stocks of influenza viruses: genetic aspects of the variations.

1950 • 15 citations

Avian influenza viruses: in avian species and the natural history of influenza.

1972 • 15 citations

An Investigation of Some Factors Affecting Cross-reactivation between Influenza A Viruses

1971 • 15 citations

INCORPORATION OF BRANCHED-CHAIN FATTY ACIDS INTO MYXOVIRUSES

1969 • 14 citations

Communications

1969 • 14 citations

ANTIGENIC VARIANTS OF INFLUENZA A VIRUS (PR8 STRAIN)

1958 • 9 citations

Influenza 1970:Unquestioned Answer and Unanswered Questions

1970 • 9 citations

Serological Studies with Equine Influenza Viruses

1966 • 8 citations

Plaque-type recombination in fowl plague virus

1964 • 7 citations