Loss of LKLF function results in embryonic lethality in mice.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

1996 • 1,885 citations

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1990 • 1,882 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1994 • 1,412 citations

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

1994 • 1,396 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

1996 • 763 citations

A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences.

1988 • 733 citations

A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

1993 • 703 citations

Identification and Characterization of a Gene Encoding a Gut-enriched Krüppel-like Factor Expressed during Growth Arrest

1996 • 647 citations

Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

1995 • 620 citations

Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

1995 • 619 citations

The transcriptional control of hematopoiesis [see comments]

1996 • 608 citations

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

1994 • 574 citations

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

1995 • 572 citations

Improved Plasma Culture System for Production of Erythrocytic Colonies In Vitro: Quantitative Assay Method for CFU-E

1974 • 524 citations

A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene

1986 • 409 citations

The GLI gene is a member of the Kruppel family of zinc finger proteins

1988 • 396 citations

Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta.

1996 • 382 citations

Site-specific recombinases: tools for genome engineering

1993 • 353 citations

A Gene for a Novel Zinc-finger Protein Expressed in Differentiated Epithelial Cells and Transiently in Certain Mesenchymal Cells

1996 • 311 citations

Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in Drosophila

1989 • 270 citations

Isolation of a Gene Encoding a Functional Zinc Finger Protein Homologous to Erythroid Krüppel-Like Factor: Identification of a New Multigene Family

1995 • 260 citations

Transcription Factors and Hematopoietic Development

1995 • 236 citations

Isolation and Characterization of the cDNA Encoding BKLF/TEF-2, a Major CACCC-Box-Binding Protein in Erythroid Cells and Selected Other Cells

1996 • 229 citations

Role of Erythroid Kruppel-like Factor in Human γ- to β-Globin Gene Switching

1995 • 212 citations

cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2

1993 • 203 citations

Analyses of beta-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor.

1994 • 194 citations

Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF.

1996 • 154 citations

Inhibition of human erythroid colony-forming units by tumor necrosis factor requires beta interferon.

1993 • 145 citations

Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy.

1993 • 125 citations

The Erythroid Krüppel-Like Factor Transactivation Domain is a Critical Component for Cell-Specific Inducibility of a β-Globin Promoter

1995 • 124 citations

Vintage reds and whites: combinatorial transcription factor utilization in hematopoietic differentiation

1994 • 52 citations

Site-Directed Point Mutations in Embryonic Stem Cells: a Gene-Targeting Tag-and-Exchange Strategy

1993 • 36 citations