Ristocetin and botrocetin involve two distinct domains of von Willebrand factor for binding to platelet membrane glycoprotein Ib.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Human blood platelet adhesion to artery subendothelium is mediated by factor VIII–Von Willebrand factor bound to the subendothelium

1979 • 652 citations

Amino acid sequence of human von Willebrand factor

1986 • 486 citations

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1983 • 469 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate--dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome.

1978 • 368 citations

Platelets fixed with paraformaldehyde: a new reagent for assay of von Willebrand factor and platelet aggregating factor.

1975 • 307 citations

von Willebrand factor. A reduced and alkylated 52/48-kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein Ib.

1986 • 270 citations

Structure of the von Willebrand factor domain interacting with glycoprotein Ib.

1988 • 208 citations

Instrument for automated synthesis of peptides

1966 • 194 citations

Demonstration and characterization of specific binding sites for factor VIII/von Willebrand factor on human platelets.

1979 • 182 citations

Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex

1989 • 167 citations

Venom coagglutinin: an activator of platelet aggregation dependent on von Willebrand factor.

1978 • 158 citations

Shear Rate Dependent Inhibition of Platelet Adhesion and Aggregation on Collagenous Surfaces by Antibodies to Human Factor VIII/von Willebrand Factor

1980 • 156 citations

Monoclonal Antibody to Human Platelet Glycoprotein I II. EFFECTS ON HUMAN PLATELET FUNCTION

1981 • 127 citations

Role of botrocetin in platelet agglutination: formation of an activated complex of botrocetin and von Willebrand factor

1989 • 124 citations

Cross-linking of a monomeric 39/34-kDa dispase fragment of von Willebrand factor (Leu-480/Val-481-Gly-718) to the N-terminal region of the .alpha.-chain of membrane glycoprotein Ib on intact platelets with bis(sulfosuccinimidyl) suberate

1989 • 122 citations

Human von Willebrand factor: a multivalent protein composed of identical subunits

1986 • 120 citations

Functional domains on von Willebrand factor. Recognition of discrete tryptic fragments by monoclonal antibodies that inhibit interaction of von Willebrand factor with platelets and with collagen.

1984 • 101 citations

Localization of a factor VIII binding domain on a 34 kilodalton fragment of the N-terminal portion of von Willebrand factor

1987 • 98 citations

Purification of the factor VIII complex

1984 • 97 citations

Binding of radioiodinated human von Willebrand factor to Bernard-Soulier, thrombasthenic and von Willebrand's disease platelets

1980 • 96 citations

Mapping of distinct von Willebrand factor domains interacting with platelet GPIb and GPIIb/IIIa and with collagen using monoclonal antibodies

1986 • 93 citations

Limited proteolysis of human von Willebrand factor by Staphylococcus aureus V-8 protease: isolation and partial characterization of a platelet-binding domain

1986 • 91 citations

Evidence that the primary binding site of von Willebrand factor that mediates platelet adhesion on subendothelium is not collagen.

1988 • 72 citations

Botrocetin (venom coagglutinin): reaction with a broad spectrum of multimeric forms of factor VIII macromolecular complex.

1983 • 66 citations

Localization of a collagen-interactive domain of human von Willebrand factor between amino acid residues Gly 911 and Glu 1,365

1987 • 59 citations

The von willebrand factor domain-mediating botrocetin-induced binding to glycoprotein IB lies between Val449 and Lys728

1987 • 58 citations

The agglutination of human platelets by botrocetin: evidence that botrocetin and ristocetin act at different sites on the factor VIII molecule and platelet membrane

1984 • 44 citations

Use of venom coagglutinin and lyophilized platelets in testing for platelet-aggregating von Willebrand factor

1980 • 42 citations

Binding of human von Willebrand factor to collagen and to collagen-stimulated platelets.

1987 • 26 citations

Production and characterization of monoclonal antibodies against von Willebrand factor (vWF).

1985 • 8 citations