Cytokines — The New Generation of Adjuvants for Vaccines?

The Effects of Cyclosporin A on the Immune System

1985 • 442 citations

Role of Cytokines and CD4+ T‐Cell Subsets in the Regulation of Parasite Immunity and Disease

1989 • 405 citations

T-cell-derived helper factor allows in vivo induction of cytotoxic T cells in nu/nu mice

1980 • 228 citations

Prevention of vaccinia virus infection in imiminodeficient mice by vector-directed IL-2 expression

1987 • 216 citations

The adjuvanticity of interleukin 1 in vivo.

1983 • 197 citations

LOW-DOSE INTERLEUKIN-2 INDUCES SYSTEMIC IMMUNE RESPONSES AGAINST HBsAg IN IMMUNODEFICIENT NON-RESPONDERS TO HEPATITIS B VACCINATION

1989 • 174 citations

Effect of IFN-γ on the immune response in vivo and on gene expression in vitro

1984 • 149 citations

Immunomodulatory properties of recombinant murine and human tumor necrosis factor.

1988 • 128 citations

Recombinant interleukin 2 as an adjuvant for vaccine-induced protection. Immunization of guinea pigs with herpes simplex virus subunit vaccines.

1988 • 114 citations

Human recombinant IL-6/B cell stimulatory factor 2 augments murine antigen-specific antibody responses in vitro and in vivo.

1988 • 110 citations

In vivo immunostimulating activity of the 163-171 peptide of human IL-1 beta.

1987 • 95 citations

Immunization with antigen and interleukin 2 in vivo overcomes Ir gene low responsiveness.

1985 • 95 citations

Recombinant gamma interferon is a potent adjuvant for a malaria vaccine in mice.

1987 • 89 citations

The role of interleukin 2 in autoimmunity

1989 • 89 citations

Turnover of Ia-peptide complexes is facilitated in viable antigen-presenting cells: biosynthetic turnover of Ia vs. peptide exchange.

1989 • 87 citations

Recombinant human IL-2 overcomes genetic nonresponsiveness to malaria sporozoite peptides. Correlation of effect with biologic activity of IL-2.

1988 • 67 citations

The induction of protective immunity to Leishmania major in the BALB/c mouse by interleukin 4 treatment

1989 • 65 citations

Recombinant murine IL-3 fails to stimulate T or B lymphopoiesis in vivo, but enhances immune responses to T cell-dependent antigens.

1988 • 49 citations

Enhancing effect of IFN-gamma on helper T cell activity and IL 2 production.

1985 • 49 citations

In vivo restoration of T cell functions by human IL-1 beta or its 163-171 nonapeptide in immunodepressed mice.

1988 • 48 citations

Interferon-gamma as an adjuvant in immunocompromised mice.

1989 • 48 citations

Enhancement of a secondary antibody response to vesicular stomatitis virus "G" protein by IFN-gamma treatment at primary immunization.

1988 • 46 citations

New Approaches to Vaccine Development

1989 • 39 citations

Enhancement of DTH reaction and inhibition of the expression of class II transplantation antigens by in vivo treatment with antibodies against gamma-interferon.

1988 • 37 citations

New approaches in vaccine development

1998 • 34 citations

Involvement of gamma interferon in antibody enhancement by adjuvants

1990 • 31 citations

Immune Responses of Cattle and Mice to the G Glycoprotein of Vesicular Stomatitis Virus

1985 • 23 citations

The Effect of Injection Methods on the Species Specificity of Serum Precipitins

1935 • 16 citations

Vaccinia‐Interleukin 2 Recombinant Virus or Exogenous Interleukin 2 Does Not Alter the Magnitude or Immune Response Gene Defects of the Cytotoxic T‐Cell Response to Vaccinia Virus in Vivo

1989 • 10 citations