Physicochemical Principles Influencing Magnetopharmaceuticals

Advanced inorganic chemistry

1973 • 7,079 citations

Brain magnetic resonance imaging with contrast dependent on blood oxygenation.

1990 • 6,189 citations

Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation.

1992 • 4,175 citations

Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging.

1992 • 3,618 citations

Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance

1973 • 3,442 citations

Oxygenation‐sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields

1990 • 2,225 citations

Paramagnetic metal complexes as water proton relaxation agents for NMR imaging: theory and design

1987 • 1,930 citations

Time course EPI of human brain function during task activation

1992 • 1,893 citations

Functional Mapping of the Human Visual Cortex by Magnetic Resonance Imaging

1991 • 1,853 citations

Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. A comparison of signal characteristics with a biophysical model

1993 • 1,740 citations

Textbook of Medical Physiology

1991 • 1,294 citations

Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field

1982 • 1,108 citations

The Magnetic Properties and Structure of Hemoglobin, Oxyhemoglobin and Carbonmonoxyhemoglobin

1936 • 1,068 citations

Isotropic Nuclear Resonance Shifts

1958 • 711 citations

Dynamic imaging with lanthanide chelates in normal brain: Contrast due to magnetic susceptibility effects

1988 • 702 citations

NMR of paramagnetic molecules in biological systems

1987 • 558 citations

Magnetic resonance imaging of blood vessels at high fields: In vivo and in vitro measurements and image simulation

1990 • 546 citations

Lanthanide probes in life, chemical and earth sciences theory and practice

1990 • 459 citations

Functional mapping of the human visual cortex at 4 and 1.5 tesla using deoxygenation contrast EPI

1993 • 449 citations

4 Tesla gradient recalled echo characteristics of photic stimulation‐induced signal changes in the human primary visual cortex

1993 • 428 citations

Echo‐planar time course MRI of cat brain oxygenation changes

1991 • 424 citations

Resolution in 13C NMR of organic solids using high-power proton decoupling and magic-angle sample spinning

1981 • 420 citations

Identification of vascular structures as a major source of signal contrast in high resolution 2D and 3D functional activation imaging of the motor cortex at l.5T preliminary results

1993 • 391 citations

MRI susceptometry: Image‐based measurement of absolute susceptibility of MR contrast agents and human blood

1992 • 380 citations

Nuclear Magnetic Resonance Shift in Metals

1949 • 376 citations

Bulk magnetic susceptibility shifts in nmr studies of compartmentalized samples: use of paramagnetic reagents

1990 • 376 citations

Functional imaging of human motor cortex at high magnetic field

1993 • 373 citations

Dynamic mapping of the human visual cortex by high-speed magnetic resonance imaging.

1992 • 371 citations

Echo-planar magnetic resonance imaging studies of frontal cortex activation during word generation in humans.

1993 • 366 citations

MR Contrast Due to Microscopically Heterogeneous Magnetic Susceptibility: Numerical Simulations and Applications to Cerebral Physiology

1991 • 352 citations

Quantitative capillary topography and blood flow in the cerebral cortex of cats: an in vivo microscopic study

1981 • 313 citations

Susceptibility contrast imaging of cerebral blood volume: Human experience

1991 • 302 citations

The sensitivity of magnetic resonance image signals of a rat brain to changes in the cerebral venous blood oxygenation

1993 • 284 citations

Perfusion imaging by nuclear magnetic resonance.

1989 • 271 citations

The Time Average Magnetic Field at the Nucleus in Nuclear Magnetic Resonance Experiments

1951 • 268 citations

The effects of iron oxides on proton relaxivity

1988 • 218 citations

Nuclear Magnetic Resonance of Paramagnetic Molecules

1965 • 181 citations

Application of spin-echo nuclear magnetic resonance to whole-cell systems. Membrane transport

1979 • 170 citations

A comprehensive approach to the analysis and interpretation of the resonances of spins 3/2 from living systems

1991 • 161 citations

Gadolinium-DTPA as a Contrast Agent in MR Imaging—Theoretical Projections and Practical Observations

1985 • 157 citations

Health and Physiological Effects of Human Exposure to Whole‐Body Four‐Tesla Magnetic Fields during MRI

1992 • 140 citations

Standardization of N.M.R. High Resolution Spectra

1957 • 138 citations

Oxygen-17 nuclear magnetic resonance kinetic study of water exchange on the lanthanide(III) aqua ions

1988 • 137 citations

Proton relaxation enhancement (PRE) in biochemistry: A critical survey

1979 • 136 citations

Nuclear Magnetic Resonance Studies of Solutions of the Rare-Earth Ions and Their Complexes. III. Oxygen-17 and Proton Shifts in Aqueous Solutions and the Nature of Aquo and Mixed Complexes

1969 • 130 citations

Effect of magnetic susceptibility on nuclear magnetic resonance signals arising from red cells: a warning

1983 • 128 citations

MEASUREMENT OF METAL CATION COMPARTMENTALIZATION IN TISSUE BY HIGH-RESOLUTION METAL CATION NMR

1987 • 128 citations

Shift Reagents in NMR Spectroscopy

1972 • 127 citations

Functional Brain Mapping Using Magnetic Resonance Imaging: Signal Changes Accompanying Visual Stimulation

1992 • 123 citations

A fast gradient‐recalled MRI technique with increased sensitivity to dynamic susceptibility effects

1992 • 122 citations

Relaxographic Imaging

1994 • 121 citations

NMR analyses of molecular conformations and conformational equilibria with the lanthanide probe method

1980 • 112 citations

The Functioning of Blood Platelets

1980 • 100 citations

The molecular environment of intracellular sodium: ²³Na NMR relaxation

1991 • 99 citations

NMR imaging techniques and applications: A review

1982 • 96 citations

Magic-angle sample spinning of liquids

1982 • 90 citations

Water proton relaxation for some lanthanide aqua ions in solution

1993 • 86 citations

Pharmacokinetic analysis of blood distribution of intravenously administered 153Gd-labeled Gd(DTPA)2− and 99MTc(DTPA) in rats

1990 • 79 citations

In vivo Na‐23 MR imaging and spectroscopy of rat brain during TmDOTP⁵⁻ infusion

1992 • 72 citations

Biomedical Magnetic Resonance Imaging: Principles, Methodology, and Applications

1989 • 71 citations

Heavy Metal Ionophores: Correlations Among Structural Parameters of Complexed Nonpeptide Polyamino Acids

1984 • 68 citations

Susceptibility changes following bolus injections

1993 • 66 citations

On the Transverse relaxation rate enhancement induced by diffusion of spins through inhomogeneous fields

1991 • 63 citations

Metal ion release from paramagnetic chelates: What is tolerable?

1991 • 62 citations

Determination of metal–proton distances and electronic relaxation times in lanthanide complexes by nuclear magnetic resonance spectroscopy

1992 • 57 citations

Comparison of Gd‐ and Dy‐chelates for T2* Contrast‐Enhanced Imaging

1991 • 56 citations

Mr imaging of cerebral perfusion by phase‐angle reconstruction of bolus paramagnetic‐induced frequency shifts

1992 • 48 citations

NMR of Paramagnetic Molecules

1993 • 43 citations

Hydration of complexone complexes of lanthanide cations

1980 • 43 citations

Perturbation of homogeneous magnetic fields by isolated single and confocal spheroids. Implications for NMR spectroscopy of cells

1989 • 42 citations

Drug targeting in magnetic resonance imaging.

1992 • 42 citations

Fundamental Concepts of NMR in Paramagnetic Systems. Part II: Relaxation Effects

1990 • 41 citations

Endogenous susceptibility contrast in myocardium during apnea measured using gradient recalled echo planar imaging

1993 • 41 citations

Use of magnetite particles as a contrast agent for MR imaging of the liver.

1990 • 40 citations

The effect of compartmental location on the proton of small molecules in cell suspensions: A cellular field gradient model

1983 • 39 citations

Iron–dextran as a magnetic susceptibility contrast agent: Flow‐related contrast effects in the T2‐weighted spin‐echo MRI of normal rat and cat brain

1992 • 37 citations

Aqueous shift reagents for high‐resolution cation NMR. VI. Titration curves for in vivo²³Na and ¹H₂O MRS obtained from rat blood

1993 • 34 citations

High‐dose applications of gadolinium chelates in magnetic resonance imaging

1991 • 33 citations

EMR of Paramagnetic Molecules

1993 • 32 citations

Concurrent quantification of tissue metabolism and blood flow via ²h/³¹P NMR in Viva iii. alterations of muscle blood flow and metabolism during sepsis

1992 • 29 citations

Proton spin relaxation for the nonlabile coordinated chelate in lanthanide shift reagents

1982 • 28 citations

31P and 23Na NMR lanthanide induced shifts in axially symmetric macrocyclic phosphonate complexes

1987 • 27 citations

Fundamental Concepts of NMR in Paramagnetic Systems Part I: The Isotropic Shift

1990 • 26 citations

Magnetic susceptibility shift selected imaging: MESSI

1990 • 21 citations

Nuclear magnetic relaxation dispersion profiles of aqueous solutions of a series of gd(nota) analogs

1992 • 20 citations

Aqueous shift reagents for high-resolution cation NMR. V. Thermodynamics of interaction of DyTTHA3− with Na+, K+, Mg 2+ , and Ca 2+

1990 • 19 citations

Bulk magnetic susceptibility induced broadening in the19F NMR of suspended leukemic cells

1993 • 17 citations

Aqueous shift reagents for high-resolution cation NMR spectroscopy. 4. [o-Bis((3-tripolyphosphato)propyloxy)benzene(-)]dysprosate(5-)

1990 • 16 citations

Correction to static tube nuclear magnetic resonance method for determination of magnetic susceptibilities of solutes in solution

1980 • 16 citations

Concurrent quantification of tissue metabolism and blood flow via ²h/³¹P NMR in Vivo. 11. validation of the deuterium nmr washout method for measuring organ perfusion

1992 • 14 citations

Concurrent quantification of tissue metabolism and blood flow via ²h/³¹P NMR in vivo. i. assessment of absolute metabolite quantification

1992 • 11 citations

Diamagnetic susceptibility effects in NMR measurements of the properties of water in polymeric membranes

1974 • 9 citations

Contrast agents for fast imaging

1991 • 5 citations

¹H‐NMR Relaxation Study of Water in Binary Solvent Mixtures in the Absence and Presence of Electrolytes

1986 • 5 citations

Introduction: SMRM workshop. Contrast enhanced magnetic resonance

1991 • 5 citations

Proton chemical shifts in aqueous solutions of the rare-earth ions as an indicator of complex formations

1967 • 5 citations