Human placental 3beta-hydroxysteroid dehydrogenase: delta5-isomerase. Demonstration of an intermediate in the conversion of 3beta-hydroxypregn-5-en-20-one to pregn-4-ene-3,20-dione.

INDUCTION AND PURIFICATION OF α- AND β-HYDROXYSTEROID DEHYDROGENASES

1956 • 207 citations

An Enzyme in Endocrine Tissues which Oxidizes Δ ⁵ -3 Hydroxy Steroids to α,β Unsaturated Ketones

1951 • 198 citations

Column Chromatography of Steroids on Sephadex LH-20

1971 • 172 citations

DISTRIBUTION OF STEROID-3β-OL-DEHYDROGENASE IN CELLULAR STRUCTURES OF THE ADRENAL GLAND

1956 • 144 citations

Enzymic isomerization of Δ5-3-ketosteroids

1955 • 139 citations

The Preparation and Properties of Crystalline Δ5-3-Ketosteroid Isomerase

1962 • 107 citations

Purification and Properties of the Δ5-3β-Hydroxysteroid Dehydrogenase-Isomerase System of Sheep Adrenal Cortical Microsomes

1974 • 72 citations

Competitive Inhibition of Adrenal Δ5-3β-Hydroxysteroid Dehydrogenase and Δ5-3-Ketosteroid Isomerase Activities by Adenosine 3',5'-Monophosphate

1970 • 64 citations

A RAPID, SENSITIVE ASSAY PROCEDURE FOR ADRENAL STEROID-3β-OL-DEHYDROGENASE ACTIVITY¹²

1961 • 56 citations

Distribution of 3-β-hydroxysteroid dehydrogenase and Δ5-3-oxosteroid isomerase in homogenate fractions of human term placenta

1965 • 51 citations

3β-Hydroxy steroid dehydrogenase activity in the mitochondria of rat adrenal homogenates

1971 • 48 citations

Further Studies of Steroidal Inhibitors of Δ⁵,3β-Hydroxysteroid Dehydrogenase and Δ⁵-Δ⁴,3-Ketosteroid Isomerase inPseudomonas testosteroniand in Bovine Adrenals

1968 • 46 citations

Gas chromatographic and mass spectrometric studies of oximes derived from 20-oxosteroids

1970 • 46 citations

Purification and properties of dehydrogenase and from bovine corpora lutea

1966 • 44 citations

Evidence for two substrate-specific Δ5-3-ketosteroid isomerases in beef adrenal glands, and their separation from 3β-hydroxysteroid dehydrogenase

1964 • 39 citations

The twin ion technique for detection of metabolites by gas chromatography-mass spectrometry: Intermediates in estrogen biosynthesis

1973 • 39 citations

Purification of steroid-induced enzymes from Pseudomonas testosteroni

1964 • 36 citations

Δ5 -3-Keto isomerases — specificity and inhibition studies in bovine adrenal homogenate fractions and distribution in rat tissues

1964 • 35 citations

The precipitation of 3β-hydroxysteroids by digitonin

1953 • 34 citations

Inhibition of α- and β-Hydroxysteroid Dehydrogenases and Steroid Δ-Isomerase by Substrate Analogues¹

1968 • 30 citations

Reversibility of Steroid Δ-Isomerase

1966 • 30 citations

Site specificity of bovine adrenal 3β-hydroxysteroid dehydrogenase and δ5-3-ketosteroid isomerase

1967 • 27 citations

Identification of O-methyloximes of ketosteroids by gas chromatography, thin-layer chromatography, mass spectra, and kinetic studies

1970 • 26 citations

The Current Status of Liquid Scintillation Counting

1971 • 25 citations

Partial separation of beef adrenal Δ5-3-ketosteroid isomerases: Androst-5-ene-3,17-dione isomerase and pregn-5-ene-3,20-dione isomerase

1964 • 24 citations

THE Δ5-3β-HYDROXYSTEROID DEHYDROGENASE OF BOVINE ADRENAL MICROSOMES

1969 • 23 citations

Δ5-3-ketosteroid isomerase: Solubilization and stabilization in beef adrenal gland preparations

1964 • 21 citations

[70a] Δ5-3-Ketosteroid isomerase from Pseudomonas testosteroni

1962 • 19 citations

Studies on the Mechanism of Action of the Δ⁵-3-Ketosteroid Isomerase from Rat Adrenal Small Particles^*

1966 • 17 citations

Conversion of progesterone to pregnenolone by rabbit testis

1965 • 17 citations

Reversal of the 3β-Hydroxysteroid Dehydrogenase-Isomerase Reactions

1964 • 16 citations

6 Kinetic Isotope Effects in Enzymic Reactions

1970 • 16 citations

Fate of 4β-hydrogen in Δ5-androstene-3,17-dione on isomerization with mammalian enzyme preparation

1968 • 15 citations

A Microassay Procedure for Δ⁵-3β-Hydroxysteroid Dehydrogenase Based on Substrate Depletion

1971 • 13 citations

Lowered Ovarian Conversion of¹⁴C-Pregnenolone to Progesterone and other Metabolites during Phenobarbital (PB) Block of PMS-Induced Ovulation in Immature Rats: Inhibition of 3β-Hydroxysteroid Dehydrogenation*

1973 • 11 citations

[21] The design of double label radioisotope experiments

1975 • 5 citations