Fanconi anemia mutation causes cellular susceptibility to ambient oxygen.

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.

1973 • 533 citations

Low oxygen concentration extends the lifespan of cultured human diploid cells

1977 • 387 citations

Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage.

1984 • 365 citations

Oxygen-dependence of chromosomal aberrations in Fanconi's anaemia

1981 • 275 citations

Induction by alkylating agents of sister chromatid exchanges and chromatid breaks in Fanconi's anemia.

1975 • 266 citations

Is Fanconi's anaemia defective in a process essential to the repair of DNA cross links?

1975 • 216 citations

The cell cycle of lymphocytes in Fanconi anemia

1982 • 150 citations

Nuclear catalyzed antibiotic free radical formation.

1982 • 149 citations

Regulation of human fibroblast growth rate by both noncycling cell fraction transition probability is shown by growth in 5-bromodeoxyuridine followed by Hoechst 33258 flow cytometry.

1983 • 121 citations

Specific cellular defects in patients with Fanconi anemia

1979 • 118 citations

Effect of superoxide dismutase and catalase on spontaneously occurring chromosome breaks in patients with Fanconi's anemia

2009 • 102 citations

Endogenous blockage and delay of the chromosome cycle despite normal recruitment and growth phase explain poor proliferation and frequent edomitosis in Fanconi anemia cells.

1985 • 89 citations

Deficiency of gamma-ray excision repair in skin fibroblasts from patients with Fanconi's anemia.

1976 • 72 citations

Oxygen-sensitive stages of the cell cycle of human diploid cells.

1978 • 72 citations

Effect of oxidants and antioxidants on chromosomal breakage in Fanconi anemia lymphocytes

1985 • 68 citations

Influence of oxygen and pH on plating efficiency and colony development of WI-38 and Vero cells

1974 • 68 citations

Density‐dependent effects of oxygen on the growth of mammalian fibroblasts in culture

1978 • 63 citations

De novo synthesis of glutathione in human fibroblasts during in vitro ageing and in some metabolic diseases as measured by a flow cytometric method

1986 • 59 citations

Suppression of cylotoxic effect of mitomycin-C by superoxide dismutase in Fanconi's anemia and dyskeratosis congenita fibroblasts

1983 • 52 citations

Deficiency of DNA ligase activity in Fanconi's anemia

1978 • 51 citations

Antioxidant status of Fanconi anemia fibroblasts

1987 • 49 citations

The effect of superoxide dismutase, catalase and l-cysteine on spontaneous and on mitomycin C induced chromosomal breakage in Fanconi's anemia and normal fibroblasts as measured by the micronucleus method

1980 • 46 citations

Growth of cultured cells from patients with Fanconi anemia

1976 • 45 citations

Abnormal NAD+ levels in cells from patients with Fanconi's anaemia

1982 • 39 citations

The subcellular particulate NADPH-dependent O2.(-)-generating oxidase from human blood monocytes: comparison to the neutrophil system

1982 • 27 citations

Investigation of the cell cycle response of normal and fanconi’s anaemia fibroblasts to nitrogen mustard using flow cytometry

1983 • 13 citations