Acidification of Endocytic Vesicles and Lysosomes

Physical chemistry of macromolecules

2007 • 3,839 citations

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Physical chemistry of macromolecules

1962 • 2,105 citations

Determination of pH: Theory and Practice

1973 • 1,384 citations

The Role of Surface Carbohydrates in the Hepatic Recognition and Transport of Circulating Glycoproteins

1974 • 1,200 citations

Determination of Intracellular pH by 31P Magnetic Resonance

1973 • 1,170 citations

pH and the recycling of transferrin during receptor-mediated endocytosis.

1983 • 1,165 citations

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 • 798 citations

Recycling receptors: The round-trip itinerary of migrant membrane proteins

1983 • 780 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

1981 • 736 citations

Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 • 672 citations

Binding of apotransferrin to K562 cells: explanation of the transferrin cycle.

1983 • 603 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents.

1983 • 558 citations

Autofluorescence of viable cultured mammalian cells.

1979 • 546 citations

Receptor-mediated endocytosis of transferrin and the uptake of fe in K562 cells: identification of a nonlysosomal acidic compartment.

1982 • 486 citations

Diphtheria toxin entry into cells is facilitated by low pH.

1980 • 467 citations

Vectorial Chemistry and the Molecular Mechanics of Chemiosmotic Coupling: Power Transmission by Proticity

1976 • 431 citations

Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances.

1981 • 424 citations

Penetration of semliki forest virus from acidic prelysosomal vacuoles

1983 • 411 citations

The receptosome: An intermediate organelle of receptor-mediated endocytosis in cultured fibroblasts

1980 • 398 citations

Lysosomes, a Laboratory Handbook

1973 • 383 citations

Identification and characterization of a proton pump on lysosomes by fluorescein-isothiocyanate-dextran fluorescence.

1982 • 379 citations

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.

1980 • 372 citations

Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell line.

1982 • 357 citations

Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes.

1981 • 341 citations

Acidification of macrophage and fibroblast endocytic vesicles in vitro.

1983 • 331 citations

Exocytosis regulates urinary acidification in turtle bladder by rapid insertion of H+ pumps into the luminal membrane.

1982 • 316 citations

Pharmacology and Toxicology of the Monovalent Carboxylic Ionophores

1982 • 311 citations

Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

1981 • 291 citations

Clathrin-coated vesicles contain an ATP-dependent proton pump.

1983 • 284 citations

Lysosomes: A laboratory handbook

1972 • 282 citations

ATP-dependent acidification of intact and disrupted lysosomes. Evidence for an ATP-driven proton pump.

1981 • 255 citations

Temporal changes of lysosome and phagosome pH during phagolysosome formation in macrophages: studies by fluorescence spectroscopy.

1981 • 254 citations

An ATP-driven proton pump in clathrin-coated vesicles.

1983 • 253 citations

Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: Apparent inhibition of receptor recycling

1980 • 252 citations

TEMPORAL CHANGES IN <scp>P</scp>H WITHIN THE PHAGOCYTIC VACUOLE OF THE POLYMORPHONUCLEAR NEUTROPHILIC LEUKOCYTE

1973 • 241 citations

Phosphomannosyl-enzyme receptors in rat liver. Subcellular distribution and role in intracellular transport of lysosomal enzymes.

1980 • 231 citations

Acidification of endocytic vesicles by an ATP-dependent proton pump.

1983 • 217 citations

Characterization of the low density lipoprotein receptor in membranes prepared from human fibroblasts.

1978 • 211 citations

The permeability properties of the lysosomal membrane

1977 • 198 citations

Fate of receptor and ligand during endocytosis of asialoglycoproteins by isolated hepatocytes.

1982 • 178 citations

Transferrin receptor in human placental brush border membranes. Studies on the binding of transferrin to placental membrane vesicles and the identification of a placental brush border glycoprotein with high affinity for transferrin.

1979 • 174 citations

Rapid acidification of endocytic vesicles containing asialoglycoprotein in cells of a human hepatoma line.

1983 • 155 citations

Antihistaminics, local anesthetics, and other amines as antiviral agents.

1981 • 104 citations

Intraphagosomal pH of Human Polymorphonuclear Neutrophils

1970 • 102 citations

The Correlation of Digestive Vacuole pH and Size with the Digestive Cycle in Paramecium caudatum¹

1982 • 98 citations

In Vitro Inhibition of Diphtheria Toxin Action by Ammonium Salts and Amines

1965 • 89 citations

Receptor-mediated endocytosis of diphtheria toxin by cells in culture.

1982 • 88 citations

Monensin blocks the transport of diphtheria toxin to the cell cytoplasm.

1982 • 86 citations

Ion distribution in lysosomal suspensions

1973 • 83 citations

Nonlysosomal vesicles (acidosomes) are involved in phagosome acidification in Paramecium.

1983 • 82 citations

The food-vacuole in Paramecium.

1947 • 81 citations

Accumulation of weak bases in relation to intralysosomal pH in cultured human skin fibroblasts

1981 • 79 citations

Acidification of phagosomes is initiated before lysosomal enzyme activity is detected.

1983 • 75 citations

Transferrin Receptor in Human Placental Brush Border Membranes

1979 • 67 citations

Clathrin and coated vesicle proteins Immunological characterization.

1981 • 60 citations

pH changes in pinosomes and phagosomes in the ameba, Chaos carolinensis.

1982 • 53 citations

Flow cytofluorometric analysis of insulin binding and internalization by swiss 3T3 cells

1982 • 53 citations

Ultrastructural immunocytochemical localization of clathrin in cultured fibroblasts

1981 • 51 citations

Effect of primary amines on interferon action

1982 • 26 citations