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Problems in experimental tumorigenesis of the pituitary gland, gonads, adrenal cortices, and mammary glands: a review.

Data up to Jan 2025

Published1959
Citations37
References132

Total Citations Per Year

Abstract

References (132)

The experimental study of tumor progression: a review.

1954 • 522 citations

METABOLISM OF THE STEROID HORMONES

1942 • 413 citations

HUMORAL HYPOTHALAMIC CONTROL OF ANTERIOR PITUITARY: A STUDY WITH COMBINED TISSUECULTURES

1955 • 365 citations

Development of Tumors in the Rat Ovary After Transplantation into the Spleen.

1944 • 255 citations

Induction of thyroid tumors in rats by a low iodine diet

1955 • 169 citations

FUNCTIONAL CORPORA LUTEA MAINTAINED FOR MONTHS BY AUTOGRAFTS OF RAT HYPOPHYSES1

1956 • 154 citations

Conditioned and autonomous neoplasms: a review.

1953 • 141 citations

Mechanism of anterior pituitary tumor induction by estrogen

1956 • 117 citations

Estrogen Production by Sertoli Cell Tumors of the Testis

1945 • 113 citations

Strain differences in response to diethylstilbestrol and the induction of mammary gland and bladder cancer in the rat.

1947 • 98 citations

SOME EFFECTS OF PROLONGED ADMINISTRATION OF ŒSTRIN IN RATS

1936 • 98 citations

Neoplastic Diseases Occurring among Mice Subjected to General Irradiation with X-Rays: II. Ovarian Tumors and Associated Lesions

1936 • 95 citations

Neoplasia and Internal Environment

1955 • 90 citations

DUAL CONTROL OF ADRENOCORTICOTROPHIN RELEASE*

1951 • 87 citations

Endocrine Interrelationnship and Spontaneous Tumors of the Adrenal Cortex in NH Mice

1947 • 84 citations

The Histologic Analysis of Mammary Tumors of Mice. I. Scope of Investigations and General Principles of Analysis<xref ref-type="fn" rid="fn1">2</xref>

1956 • 83 citations

The effects of prolonged œstrogen administration upon male mice of various strains: Development of testicular tumours in the strong a strain

1940 • 73 citations

Hormonal Aspects of Experimental Tumorigenesis

1953 • 72 citations

FUNDAMENTAL FACTORS IN THE INTERPRETATION OF STIMULI INFLUENCING ENDOCRINE GLANDS

1936 • 67 citations

ACTH Secreting Transplantable Pituitary Tumors.

1953 • 66 citations

Mammary Tumor Development in Mice Ovariectomized at Birth

1939 • 63 citations

Possible relationship of the estrogenic hormones, genetic susceptibility, and milk influence in the production of mammary cancer in mice.

1942 • 62 citations

Chronic Iodine Deficiency as Cause of Neoplasia in Thyroid and Pituitary of Aged Rats

1953 • 59 citations

EFFECT OF DIETHYLSTILBESTROL-INDUCED TUMORIGENESIS ON THE SECRETORY ACTIVITY OF THE RAT ANTERIOR PITUITARY GLAND1

1956 • 56 citations

The Effects of Transplants of Anterior Lobes of the Hypophysis on the Growth of the Mammary Gland and on the Development of Mammary Gland Carcinoma in Various Strains of Mice

1939 • 54 citations

The morphogenesis of pituitary tumors induced by radiothyroidectomy in the mouse and the effects of their transplantation on the pituitary body of the host.

1954 • 54 citations

The Influence of the Thyroid in Malignant Disease

1954 • 53 citations

The Incidence of Adrenal Cortical Carcinoma in Gonadectomized Female Mice of the Extreme Dilution Strain. I. Observations on the Adrenal Cortex

1945 • 52 citations

Production of Pituitary Tumors in Mice by Chronic Administration of a Thiouracil Derivative.

1953 • 51 citations

Spontaneous basophilic tumors of the pituitary glands in gonadectomized mice.

1949 • 47 citations

Tumor of Rat Testis Produced by Heterotransplantation of Infantile Testis to Spleen of Adult Castrate

1945 • 45 citations

Neoplastic Transformation of Granulosa Cells in Grafts of Normal Ovaries into Spleens of Gonadectomized Mice<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1947 • 45 citations

Leydig-cell tumors induced experimentally in the rat

1949 • 44 citations

Late effects of thermal neutron irradiation in mice.

1954 • 43 citations

INHIBITION OF MAMMARY GROWTH BY LARGE AMOUNTS OF ESTROGEN1

1941 • 42 citations

The role of hormones in cancer: laboratory animals.

1957 • 42 citations

Ovarian and Lymphoid Tumors in Female Mice Subsequent to Roentgen-Ray Irradiation and Hormone Treatment.

1950 • 41 citations

Late Pathologic Effects of Atomic Detonation and Their Pathogenesis

1959 • 41 citations

HORMONAL INFLUENCES ON MAMMARY TUMORS OF THE RAT

1956 • 41 citations

Hormonal imbalances in tumorigenesis.

1948 • 40 citations

Hypervolemia Secondary to Grafted Granulosa-Cell Tumor<xref ref-type="fn" rid="fn2"><sup>2</sup></xref>

1946 • 39 citations

Experimental pituitary tumors and the role of pituitary hormones in tumorigenesis of the breast and thyroid

1957 • 39 citations

Histologic and physiologic characteristics of hormone-secreting transplantable adrenal tumors in mice and rats.

1957 • 36 citations

FAMILIAL MAMMARY TUMORS IN THE RABBIT

1939 • 36 citations

Experimental Studies on the Pathogenesis and Histogenesis of Ovarian Tumors in Mice

1947 • 36 citations

Studies on the influence of the central nervous system on anterior pituitary function.

1957 • 35 citations

Sex hormone secretion by tumors of the adrenal cortex of mice.

1949 • 34 citations

THE EFFECT OF TESTOSTERONE, TESTOSTERONE PROPIONATE AND DEHYDROANDROSTERONE ON THE SECRETION OF THE GONADOTROPIC COMPLEX AS EVIDENCED IN PARABIOTIC RATS1

1937 • 34 citations

Neoplasia in the parakeet. I. Spontaneous chromophobe pituitary tumors.

1954 • 34 citations

Morphological and biological characteristics of X-ray induced transplantable ovarian tumors.

1949 • 34 citations

The effects of pituitary and adrenal hormones on the growth of a transplanted mammary adenocarcinoma in C3H mice

1955 • 33 citations

Cytochemical studies of the anterior hypophyses of rats receiving estrogen

1949 • 33 citations

Development and growth of tumors in ovaries transplanted in the spleen.

1955 • 33 citations

Factors influencing the development and time of appearance of mammary cancer in the rat in response to estrogen.

1942 • 33 citations

The effect of exogenous gonadotrophins on the development of experimental ovarian tumors in rats.

1953 • 32 citations

Morphologic changes associated with thyrotrophin-secreting pituitary tumors.

1954 • 32 citations

Mammary tumors in mice presumable free of the mammary-tumor agent.

1948 • 31 citations

In vitro Response of Functional Experimental Adrenal Tumors to Corticotropin (ACTH).

1957 • 31 citations

Discussion of problems related to hormonal factors in initiating and maintaining tumor growth.

1957 • 31 citations

Effect of Discontinued Estrogenic Stimulation upon the Development and Growth of Testicular Tumors in Mice

1957 • 29 citations

The Production of Mammary Cancer in Rats Using Oestrogens

1955 • 29 citations

EFFECT OF A PRIMATE PITUITARY GROWTH HORMONE PREPARATION ON NITROGEN METABOLISM IN THE HYPOPHYSECTOMIZED RHESUS MONKEY1

1957 • 29 citations

The Induction of Mammary Carcinoma in the Rat.

1944 • 29 citations

Differences in adrenal responsiveness to postcastrational alteration as evidenced by transplanted adrenal tissue.

1951 • 29 citations

Influence of Ovarian Function on Incidence of Radiation-Induced Ovarian Tumors in Mice<xref ref-type="fn" rid="fn1"><sup>2</sup></xref>

1950 • 28 citations

Growth of the Mammary Glands in Hypophysectomized Mice.

1940 • 27 citations

THE ADRENAL CORTEX AND ITS TUMORS

1949 • 26 citations

Strain-limited Development of Tumors of the Pituitary Gland in Mice Receiving Estrogens.

1940 • 25 citations

Demonstration of Increased Gonadotrophic Hormone Production in Castrated Mice with Intrasplenic Ovarian Grafts.

1950 • 25 citations

Autonomous Transplantable Pituitary Tumors Arising in Growths Dependent on Absence of the Thyroid Gland.

1952 • 25 citations

The influence of pregnancies on the incidence of cancer in mice

1913 • 25 citations

Body Composition and Energetics in Obesity Induced in Mice by Adrenotropic Tumors

1956 • 25 citations

Quantitative relationship between thyroid function and growth of pituitary tumors secreting TSH.

1953 • 24 citations

Ovary transplanted to spleen in rats: the effect of unilateral castration, pregnancy, and subsequent castration.

1950 • 24 citations

Hormonal regulation of tumor growth.

1957 • 23 citations

Mammary Tumours in Hybrid Mice: Hormone-Responses of Transplanted Tumours

1949 • 22 citations

Adrenal tumors and other pathological changes in reciprocal crosses in mice. II. An introduction to results of four reciprocal crosses.

1953 • 22 citations

Effect of diethylstilbestrol on the quantity and intracellular distribution of pituitary proteinase activity

1956 • 21 citations

Growth of Human Epidermoid Carcinomas (Strains KB and HeLa) in Hamsters from Tissue Culture Inocula.

1956 • 20 citations

Effect of Progestin upon the Mammary Glands of the Mouse.

1936 • 19 citations

STEROIDS IN THE BLOOD AND URINE OF FEMALE MICE BEARING AN ACTH-PRODUCING PITUITARY TUMOR1

1958 • 19 citations

The influence of estrogen on cancer incidence and adrenal changes in ovariectomized mice on calorie restriction.

1949 • 19 citations

The Effectiveness of Ovarian and Hypophysial Grafts in the Production of Mammary Carcinoma in Mice

1944 • 19 citations

A New Strain of Mice with a High Incidence of Mammary Cancers and Enlargement of the Pituitary

1956 • 19 citations

Transplantability of Induced Granulosa Cell Tumors and of Luteoma in Mice. Secondary Effects of These Growths.

1946 • 18 citations

Control of cancers of man by endocrinologic methods.

1957 • 18 citations

Induction of Mammary Growth in Rats by Estrogen and Progesterone.,

1954 • 18 citations

EFFECTS OF 3-METHYLCHOLANTHRENE ON THE ENDOCRINE SYSTEM AND METABOLISM OF THE RAT AND ITS INFLUENCE TO RETARD GROWTH OF MAMMARY TUMORS HITHERTO REFRACTORY

1958 • 18 citations

Further studies on the relation of dietary tryptophan to the induction of neoplasms in rats.

1954 • 17 citations

Direct Action of Estrone on the Mammary Gland

1940 • 17 citations

Incidence of Mammary and Pituitary Tumors in Hybrid Mice Treated with Stilbestrol for Varying Periods<xref ref-type="fn" rid="FN1">2</xref>

1957 • 16 citations

Autonomous mammotropic pituitary tumors in mice; their somatotropic features and responsiveness to estrogens.

1956 • 16 citations

Histological Study of Adrenal Cortical Tumors in Gonadectomized Mice of the ce Strain

1945 • 15 citations

Oestrogenic Treatment of Hypophysectomized Male Mice.

1937 • 14 citations

Action of testosterone propionate on the output of pituitary gonadotrophins in mice.

1955 • 14 citations

Pituitary and Adrenal Glands

1957 • 14 citations

THE ACTION OF BOVINE, PORCINE AND SIMIAN GROWTH HORMONE PREPARATIONS ON THE COSTOCHONDRAL JUNCTION IN THE HYPOPHYSECTOMIZED RHESUS MONKEY12

1958 • 14 citations

THE EFFECT OF THE INTRASPLENIC OVARIAN GRAFT ON PITUITARY GONADOTROPINS*

1951 • 13 citations

Induced Ovarian and Adrenal Tumors<xref ref-type="fn" rid="fn1">1</xref><xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1954 • 13 citations

Occurrence of Melanocyte Stimulating Hormone (MSH) in a Transplantable Pituitary Tumor

1956 • 13 citations

Transplantable Adrenocortical Adenocarcinomas in Osborne-Mendel Rats Fed a Carcinogenic Diet

1955 • 13 citations

Adrenal tumors, pituitary tumors, and other pathological changes in F hybrids of strain DE x strain DBA.

1956 • 12 citations

THE EFFECT OF ESTROGEN AND PROGESTERONE ON MAMMARY GLAND GROWTH IN THE RAT

1955 • 12 citations

An appraisal of the concepts of endocrine influence on the etiology, pathogenesis, and control of abnormal and neoplastic growth.

1957 • 12 citations

Effects of X-Ray Irradiation on the Development of Ovarian Tumors in Intrasplenic Grafts in Castrated Mice<xref ref-type="fn" rid="fn1"><sup>2</sup></xref>

1947 • 11 citations

EFFECT OF ESTRONE, PROGESTERONE AND PITUITARY MAMMOTROPIN ON THE MAMMARY GLANDS OF CASTRATED C3H MALE MICE

1954 • 11 citations

Testicular Changes Resembling Early Stages in the Development of Interstitial Cell Tumors in Mice of the A Strain after Long-Continued Injections of Pregnant Mare Serum

1943 • 11 citations

ANTILUTEOMATOUS ACTION OF PROGESTERONE IN THE GUINEA-PIG

1950 • 11 citations

Transplantable luteoma in mice and associated secondary changes.

1947 • 11 citations

Morphology, secretion, and transplantability of ten mouse ovarian neoplasms induced by intrasplenic ovarian grafting.

1957 • 11 citations

OVARIAN ANDROGENS IN PARABIOTIC RATS1

1958 • 11 citations

The role of thyroid function and food intake in experimental ovarian tumorigenesis in mice.

1954 • 10 citations

Role of Ionizing Radiation in Eliciting Tumors of the Pituitary Gland in Mice.

1952 • 10 citations

The Morphology and Growth Characteristics of a Transplantable Mammary Fibroadenoma in the Rat

1954 • 10 citations

Effect of Estrogens and Androgens on Growth of Mammary Fibroma in Rats.

1940 • 10 citations

Effect of Antigonadotrophic Serum on Testes of A-Strain Mice Treated with Estrogen

1953 • 9 citations

EFFECT OF ANTIGONADOTROPHIC SERUM ON RECENT INTRASPLENIC OVARIAN IMPLANTS OF CASTRATE MICE1

1956 • 9 citations

Prolactin and Thyrotrophin Content of Functional Transplantable Pituitary Tumors

1956 • 9 citations

THYROTROPHIN POTENCY OF TRANSPLANTABLE PITUITARY TUMORS OF MICE THROUGH FOUR TRANSFERS

1957 • 9 citations

The Effect of Hormonal Environment on the Latent Period of a Grafted Interstitial Cell Carcinoma of the Testis

1954 • 9 citations

Action of Estradiol Monobenzoate on the Mammary Glands of Hypophysectomized Rabbits.

1954 • 9 citations

Effect of Pituitary Growth Hormone on Transplantable Mouse Tumors

1957 • 8 citations

Failure of Hypothalamic Tissue to Reinitiate Thyrotropin Production By Mouse Pituitaries in Tissue Culture.

1957 • 8 citations

Transplantable Leydig-cell tumors in mice; their physiologic and pathologic effects.

1956 • 7 citations

STIMULATION OF ANTERIOR HYPOPHYSIS METABOLISM BY THEELIN OR DIHYDROTHEELIN

1937 • 7 citations

Effects of administration of estrogens upon enzymes of rat pituitary. I. beta-Glucuronidase and phosphatases.

1956 • 7 citations

HORMONAL INFLUENCE ON TESTIS GRAFTS IN THE SPLEENS OF RATS

1957 • 5 citations

Spontaneous mammary cancer in mice of the CE stock.

1954 • 5 citations

Pathogenesis and character of radiation-induced pituitary tumors.

1960 • 5 citations

Postcastrational adrenal tumors in unilaterally adrenalectomized C3H mice.

1955 • 5 citations

STUDIES IN CASTRATED FEMALE RATS WITH OVARIAN TISSUE TRANSPLANTED IN THE SPLEEN

1954 • 4 citations

Summary of Informal Discussion of First Day

1957 • 2 citations

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