Correlation between the kinetics of Th1, Th2 cells and pathology in a murine model of experimental pulmonary tuberculosis.

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples.

1993 • 2,807 citations

Differing Lymphokine Profiles of Functional Subsets of Human CD4 and CD8 T Cell Clones

1991 • 1,027 citations

Interleukin-12 and its role in the generation of TH1 cells

1993 • 869 citations

Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines.

1991 • 835 citations

Gamma/Delta Cells

1993 • 819 citations

Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni.

1991 • 542 citations

Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis.

1991 • 528 citations

Role of T‐Cell Derived Cytokines in the Downregulation of Immune Responses in Parasitic and Retroviral Infection

1992 • 473 citations

Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells.

1988 • 389 citations

Defining protective responses to pathogens: cytokine profiles in leprosy lesions

1991 • 375 citations

Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection.

1993 • 359 citations

Distinct types of lung disease caused by functional subsets of antiviral T cells.

1994 • 318 citations

Production of IL-10 by CD4+ T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection.

1991 • 312 citations

Th1/Th2 profiles in tuberculosis, based on the proliferation and cytokine response of blood lymphocytes to mycobacterial antigens.

1994 • 309 citations

Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones

1991 • 287 citations

T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection. Evidence for different kinetics and recognition of a wide spectrum of protein antigens.

1992 • 256 citations

The role of TNF-alpha in T-cell-mediated inflammation depends on the Th1/Th2 cytokine balance.

1994 • 205 citations

Down-regulation of immune responses in the lower respiratory tract: the role of alveolar macrophages.

1986 • 187 citations

Immune regulation: a new role for the CD8+ T cell

1994 • 179 citations

T Lymphocytes in Human Tuberculosis

1992 • 164 citations

Early appearing gamma/delta-bearing T cells during infection with Calmétte Guérin bacillus.

1991 • 133 citations

The Use of Fluorescein Diacetate and Ethidium Bromide as a Stain for Evaluating Viability of Mycobacteria

1980 • 94 citations

Gamma interferon and interleukin 2, but not interleukin 4, are detectable in gamma/delta T-cell cultures after activation with bacteria

1992 • 87 citations

Cytokine gene expression in the lungs of BALB/c mice during primary and secondary intranasal infection with Mycoplasma pneumoniae

1994 • 62 citations

Application of knockout mice to the experimental analysis of infections with bacteria and protozoa

1994 • 47 citations

T Cell Helper Types and Endocrines in the Regulation of Tissue-Damaging Mechanisms in Tuberculosis

1994 • 28 citations

Production of a suppressor factor by CD8+ lymphocytes activated by mycobacterial components

1991 • 22 citations