Alcohol and Aldehyde Metabolism in Brain

Methods in Enzymology , Vol

1966 • 26,261 citations

Effect of Ischemia on Known Substrates and Cofactors of the Glycolytic Pathway in Brain

1964 • 2,227 citations

3 Alcohol Dehydrogenases

1975 • 706 citations

Alcohol, Amines, and Alkaloids: A Possible Biochemical Basis for Alcohol Addiction

1970 • 558 citations

Alkaloids from Catecholamines in Adrenal Tissue: Possible Role in Alcoholism

1970 • 441 citations

Properties of catalase. Catalysis of coupled oxidation of alcohols

1945 • 441 citations

Relationship of alcohol dose to intensity of withdrawal signs in mice.

1972 • 329 citations

SELECTIVE ACTION OF ANESTHETICS ON SYNAPSES AND AXONS IN MAMMALIAN SYMPATHETIC GANGLIA

1952 • 329 citations

The metabolism of ethanol and its metabolic effects.

1972 • 291 citations

Bioenergetics Bulletin Prospers

1970 • 281 citations

Tyramine oxidase

1928 • 276 citations

The role of H2O2 generation in perfused rat liver and the reaction of catalase compound I and hydrogen donors

1973 • 271 citations

The time-course of the effects of ethanol on the redox and phosphorylation states of rat liver

1972 • 250 citations

Alcohol and Aldehyde Metabolizing Systems-IV

1980 • 241 citations

Tissue and subcellular distribution of mammalian aldehyde-oxidizing capacity

1966 • 237 citations

Ethanol and acetaldehyde metabolism in rat strains genetically selected for their ethanol preference

1973 • 229 citations

Metabolic pathways of dopamine and norepinephrine in rabbit brain in vitro.

1967 • 215 citations

Compartmentation of Amino Acid Metabolism

1969 • 209 citations

ALDEHYDE DEHYDROGENASE, A DIPHOSPHOPYRIDINE NUCLEOTIDE-LINKED ENZYME

1949 • 203 citations

Brain Aldehyde Dehydrogenase

1966 • 201 citations

[78] Liver alcohol dehydrogenase

1955 • 195 citations

Compartmentation of glutamate metabolism in brain. Evidence for the existence of two different tricarboxylic acid cycles in brain

1969 • 193 citations

Human Liver-Alcohol Dehydrogenase. Kinetic and Physicochemical Properties^*

1964 • 193 citations

The alteration of serotonin metabolism to 5-hydroxytryptophol by ethanol ingestion in man.

1967 • 192 citations

Effects of ethanol on central and peripheral noradrenergic neurons.

1974 • 188 citations

Horse Liver Aldehyde Dehydrogenase

1972 • 180 citations

Liver Alcohol Dehydrogenase. II. Equilibrium Constants of Binary and Ternary Complexes of Enzyme, Coenzyme, and Caprate, Isobutyramide and Imidazole.

1961 • 177 citations

PRECURSORS IN VIVO OF GLUTAMATE, ASPARTATE AND THEIR DERIVATIVES OF RAT BRAIN

1966 • 177 citations

Studies on Liver Alcohol Dehydrogenase. III. The Influence of pH and Some Anions on the Reaction Velocity Constants.

1955 • 159 citations

Aldehyde Dehydrogenase and Ethanol Preference in Mice

1970 • 145 citations

Adrenal Function and Alcoholism

1971 • 135 citations

Ethanol-induced alterations of norepinephrine metabolism in man.

1967 • 131 citations

Heterogeneity of NADPH-Dependent Aldehyde Reductase from Human and Rat Brain

1973 • 127 citations

Ethyl alcohol metabolism in animal tissues

1938 • 125 citations

Coupled oxidation of alcohol

1936 • 124 citations

ENZYMES CATALYSING ETHANOL METABOLISM IN NEURAL AND SOMATIC TISSUES OF THE RAT

1972 • 117 citations

The Metabolism of Alcohol

1976 • 116 citations

The characterization of two reduced nicotinamide–adenine dinucleotide phosphate-linked aldehyde reductases from pig brain

1972 • 107 citations

ALCOHOL DEHYDROGENASE ACTIVITY IN RAT BRAIN AND LIVER

1970 • 107 citations

Genetic Aspects of Increase in Rat Liver Aldehyde Dehydrogenase Induced by Phenobarbital

1971 • 105 citations

Oxidation of Acetaldehyde by Rat‐Liver Mitochondria in Relation to Ethanol Oxidation and the Transport of Reducing Equivalents across the Mitochondrial Membrane

1973 • 101 citations

ACATALASEMIC AND HYPOCATALASEMIC MOUSE MUTANTS

1966 • 99 citations

Genetic Influence upon Phenobarbital-induced Increase in Rat Liver Supernatant Aldehyde Dehydrogenase Activity

1972 • 96 citations

Acatalasemic and hypocatalasemic mouse mutants

1967 • 93 citations

Acetaldehyde—an inhibitor of the enzymatic oxidation of 5-hydroxyindoleacetaldehyde

1969 • 93 citations

Alcohol dehydrogenase of animal tissues

1938 • 92 citations

Heterogenität und Organverteilung der Alkoholdehydrogenase bei verschiedenen Spezies

1968 • 89 citations

The Enzymatic Synthesis of Sphingosine

1958 • 86 citations

EFFECTS OF ETHANOL ON SEROTONIN METABOLISM IN BRAIN

1974 • 85 citations

Brain Alcohol Dehydrogenase

1968 • 83 citations

The effect of ethanol metabolism on levels of oxidized and reduced nicotinamide-adenine dinucleotide in liver, kidney, and heart

1965 • 80 citations

THE EFFECTS OF INTOXICATING DOSES OF ETHANOL UPON INTERMEDIARY METABOLISM IN RAT BRAIN

1972 • 80 citations

THE EFFECTS OF ALIPHATIC ALCOHOLS ON THE RESPIRATION OF RAT BRAIN CORTEX SLICES AND RAT BRAIN MITOCHONDRIA

1958 • 71 citations

Effect of ethanol on respiration of rat-brain-cortex slices

1960 • 70 citations

Enzymatic reduction of "biogenic" aldehydes in brain.

1973 • 68 citations

SOME ENZYMIC ASPECTS OF THE PRODUCTION OF OXIDIZED OR REDUCED METABOLITES OF CATECHOLAMINES AND 5‐HYDROXYTRYPTAMINE BY BRAIN TISSUES

1974 • 67 citations

Metabolism of some phenylethylamines and their beta-hydroxylated analogs in brain.

1969 • 63 citations

Structure and Function Relationships in Isoenzymes of Horse Liver Alcohol Dehydrogenase

1969 • 62 citations

The Purification and Properties of an NADPH‐Linked Aldehyde Reductase from Pig Brain

1972 • 61 citations

Some Observations on Alcohol Metabolism with Radioactive Ethyl Alcohol

1949 • 60 citations

The Metabolism of Alcohol in Normals and Alcoholics: Enzymes

1971 • 59 citations

The metabolism of 1,2-propanediol

1961 • 58 citations

Aldehyde Dehydrogenases in Rat Liver

1972 • 57 citations

Effect of Ethanol and Acetaldehyde on Liver and Brain Monoamine Oxidase

1964 • 56 citations

Effects of pyrazole and 3-amino-1,2,4-triazole on methanol and ethanol metabolism by the rat

1973 • 55 citations

On the contribution of the tricarboxylic acid cycle to the synthesis of glutamate, glutamine and aspartate in brain

1966 • 55 citations

The metabolism of acetaldehyde by the brain in vivo

1963 • 54 citations

THE FORMATION OF 5‐HYDROXYTRYPTOPHOL IN BRAIN IN VITRO

1966 • 54 citations

Biogenic Amines, Biogenic Aldehydes, and Alcohol

1964 • 51 citations

5‐Hydroxytryptamine metabolism in brain and liver slices and the effects of ethanol

1969 • 51 citations

METABOLIC CONSEQUENCES OF ETHANOL OXIDATION IN BRAINS FROM MICE CHRONICALLY FED ETHANOL

1973 • 46 citations

The Purification and Properties of the NAD‐Linked Aldehyde Dehydrogenase from Pig Brain

1971 • 46 citations

Function and structure of liver alcohol dehydrogenase.

1967 • 44 citations

Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro

1973 • 44 citations

Mammalian Liver Alcohol Dehydrogenases

1975 • 43 citations

The effect of acetaldehyde on rat brain mitochondria and its occurrence in brain after alcohol injection

1962 • 39 citations

Studies on the metabolism of acetate-1-C in tissues of tumor-bearing rats.

1953 • 38 citations

The Enzymatic Conversion of Lactaldehyde to Propanediol

1960 • 37 citations

THE METABOLISM OF ACETALDEHYDE

1945 • 37 citations

PURIFICATION AND CHARACTERIZATION OF AN NADH‐LINKED ALDEHYDE REDUCTASE FROM BOVINE BRAIN¹

1972 • 36 citations

Metabolism of C¹⁴-Ethanol by Surviving Rat Tissues

1953 • 36 citations

CHANGES IN BRAIN ALCOHOL DEHYDROGENASE ACTIVITY DURING CHRONIC ETHANOL INGESTION AND WITHDRAWAL

1974 • 36 citations

Acetaldehyde mediation in the mechanism of ethanol-induced changes in norepinephrine metabolism.

1970 • 36 citations

Inhibition of a reduced nicotinamide adenine dinucleotide phosphate-linked aldehyde reductase from bovine brain by barbiturates.

1971 • 35 citations

5-Hydroxytryptamine metabolism in rat brain and liver homogenates

1968 • 35 citations

Ethanol-induced Adaptation of Alcohol Dehydrogenase Activity in Rat Brain

1972 • 34 citations

The effects of acetaldehyde on serotonin metabolism

1967 • 31 citations

Cholesterol Ester Fatty Acids in Serum and Liver of Normal and Lymph-fistula Rats

1960 • 29 citations

Acetaldehyde in Relation to Intoxication by Ethyl Alcohol

1950 • 29 citations

The effect of acetaldehyde on mitochondrial respiration

1963 • 28 citations

EFFECTS OF ALIPHATIC ALCOHOLS AND ALDEHYDES ON THE METABOLISM OF POTASSIUM-STIMULATED RAT BRAIN CORTEX SLICES

1965 • 28 citations

ACETALDEHYDE OXIDATION IN MOLYBDENUM DEFICIENCY

1957 • 28 citations

“Biogenic” aldehyde metabolism relation to pentose shunt activity in brain

1974 • 27 citations

Further characterization of a reduced nicotinamide-adenine dinucleotide phosphate-dependent aldehyde reductase from bovine brain

1972 • 27 citations

Metabolism of ethanol and acetaldehyde by the isolated perfused rat brain.

1975 • 27 citations

Aldehyde Derivatives of Indoleamines and the Enhancement of their Binding onto Brain Macromolecules by Pentobarbital and Acetaldehyde

1972 • 27 citations

THE EFFECTS OF ALIPHATIC ALDEHYDES ON THE RESPIRATION OF RAT BRAIN CORTEX SLICES AND RAT BRAIN MITOCHONDRIA

1958 • 27 citations

Substrate Characteristics of Human Liver Aldehyde Dehydrogenase

1971 • 26 citations

Alcohol dehydrogenase activity in rat brain: evidence for the metabolism of succinic semialdehyde to gamma-hydroxybutyrate

1974 • 24 citations

The metabolism of alcohol.

1955 • 24 citations

Effect of crystallization upon the reactivity of horse liver alcohol dehydrogenase

1966 • 24 citations

The Form of the Aldehyde Susceptible to Enzymic Oxidation

1968 • 21 citations

Reduction of chloral hydrate to trichloroethanol in brain extracts

1974 • 19 citations

Incorporation of label from [1-14C]ethanol into the glutamate–glutamine pools of rat brain in vivo

1972 • 18 citations

Ethanol Oxidation by Human Erythrocytes

1973 • 18 citations

PARTIAL PURIFICATION AND CHARACTERIZATION OF NADPH‐LINKED ALDEHYDE REDUCTASE FROM MONKEY BRAIN¹

1973 • 17 citations

[2-14C]Ethanol as a precursor of glutamine, glutamate, γ-aminobutyric acid and aspartate in hamster brain in vivo

1972 • 17 citations

The effect of ethanol and disulfiram on serotonin-14C metabolism in rat liver homogenates

1968 • 16 citations

Gekoppelte Oxydation von Formiat und Thiolverbindungen durch Katalase

1958 • 13 citations

Observations on the histochemical distribution of alcohol dehydrogenase

1965 • 13 citations

The inhibition of alcohol and aldehyde dehydrogenases by propranolol.

1973 • 10 citations

The influence of neuroamines on the oxidation of glucose by the anterior pituitary II. Effect on TPNH oxidation

1963 • 9 citations

Addiction to Barbiturates and Ethanol: Possible Biochemical Mechanisms

1973 • 8 citations

The activity of oxidative enzymes in neuroglia cultivated in vitro. I. Dehydrogenases linked with coenzyme I and succinic dehydrogenase.

1966 • 2 citations

Deleted Work

1955 • 0 citations